Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Theresa Lindhout"'
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69888 (2013)
Polysialic acids are bioactive carbohydrates found in eukaryotes and some bacterial pathogens. The bacterial polysialyltransferases (PSTs), which catalyze the synthesis of polysialic acid capsules, have previously been identified in select strains of
Externí odkaz:
https://doaj.org/article/8abcc6dff2a54382b28b42a890d6aeaa
Autor:
Lingquan Deng, Theresa Lindhout-Djukic, Melissa J. Schur, Lisa A. Lewis, Ajit Varki, Sunita Gulati, Sanjay Ram, Corinna S. Landig, Sudeshna Saha, Ian C. Schoenhofen, Bo Zheng
Publikováno v:
The Journal of Immunology. 204:3283-3295
Neisseria gonorrhoeae deploys a unique immune evasion strategy wherein the lacto-N-neotetraose termini of lipooligosaccharide (LOS) are “capped” by a surface LOS sialyltransferase (Lst), using extracellular host-derived CMP-sialic acid (CMP-Neu5A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b60cae5627fc81ae4c669390a72415
https://doi.org/10.4049/jimmunol.1901398
https://doi.org/10.4049/jimmunol.1901398
Autor:
Theresa Lindhout, Will J. Costain, Michel Gilbert, Cynthia R. Bainbridge, Warren W. Wakarchuk
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69888 (2013)
PLoS ONE
PLoS ONE
Polysialic acids are bioactive carbohydrates found in eukaryotes and some bacterial pathogens. The bacterial polysialyltransferases (PSTs), which catalyze the synthesis of polysialic acid capsules, have previously been identified in select strains of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02cae80d2900966b602f11e40e6d572
https://doi.org/10.32920/14637984.v1
https://doi.org/10.32920/14637984.v1
Autor:
Lisa A. Lewis, Ajit Varki, Peter A. Rice, Ian C. Schoenhofen, Iesha Y Moustafa, Sunita Gulati, Sanjay Ram, Theresa Lindhout-Djukic, Bo Zheng, Sudeshna Saha, Nancy A. Nowak
Publikováno v:
J Infect Dis
Novel therapies to counteract multidrug-resistant gonorrhea are urgently needed. A unique gonococcal immune evasion strategy involves capping of lipooligosaccharide (LOS) with sialic acid by gonococcal sialyltransferase (Lst), utilizing host-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593ecdc4ca49f48f711408adabdb9614
https://pubmed.ncbi.nlm.nih.gov/32692362
https://pubmed.ncbi.nlm.nih.gov/32692362
Autor:
Sunita, Gulati, Ian C, Schoenhofen, Theresa, Lindhout-Djukic, Melissa J, Schur, Corinna S, Landig, Sudeshna, Saha, Lingquan, Deng, Lisa A, Lewis, Bo, Zheng, Ajit, Varki, Sanjay, Ram
Publikováno v:
J Immunol
Neisseria gonorrhoeae deploys a unique immune evasion strategy wherein the lacto-N-neotetraose (LNnT) termini of lipooligosaccharide (LOS) are capped by a surface sialyltransferase (Lst), utilizing extracellular host-derived CMP-sialic acid (CMP-Neu5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bcb3171ca6891c6eeeffda75e2c7aab
https://pubmed.ncbi.nlm.nih.gov/32434942
https://pubmed.ncbi.nlm.nih.gov/32434942
Autor:
Damien D. Pearse, Theresa Lindhout, Abderrahman El Maarouf, Damali Moyo Lee Yaw, Urs Rutishauser, Warren W. Wakarchuk
Publikováno v:
Journal of Biological Chemistry. 287:32770-32779
In vertebrates, polysialic acid (PSA) is typically added to the neural cell adhesion molecule (NCAM) in the Golgi by PST or STX polysialyltransferase. PSA promotes plasticity, and its enhanced expression by viral delivery of the PST or STX gene has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05c9ceadcc78d57843ec9b842deed90
https://doi.org/10.1074/jbc.m112.377614
https://doi.org/10.1074/jbc.m112.377614
Autor:
Theresa Lindhout, Xin Liu, Jianjun Li, Umar Iqbal, Lisa M. Willis, María Ángeles Moreno, Anne N. Reid, Warren W. Wakarchuk
Publikováno v:
Proceedings of the National Academy of Sciences. 108:7397-7402
The posttranslational modification of therapeutic proteins with terminal sialic acids is one means of improving their circulating half-life, thereby improving their efficiency. We have developed a two-step in vitro enzymatic modification of glycoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48fae47d03007feb7cdb02c1e902d3d
https://doi.org/10.1073/pnas.1019266108
https://doi.org/10.1073/pnas.1019266108
Publikováno v:
Microbiology. 155:3449-3460
In many Gram-negative bacterial species, rough strains producing truncated lipopolysaccharide (LPS) generally exhibit defects in motility compared with smooth strains. However, the role that LPS plays in bacterial motility is not well understood. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967e986fb3221585b3d9d8186dc06b98
https://doi.org/10.1099/mic.0.030510-0
https://doi.org/10.1099/mic.0.030510-0
Bacterial biofilms are responsible for the majority of all microbial infections and have profound impact on industrial and geochemical processes. While many studies documented phenotypic differentiation and gene regulation of biofilms, the importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dabf7da3122dc8e740c6f2983a36402
https://europepmc.org/articles/PMC2795305/
https://europepmc.org/articles/PMC2795305/