Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Theresa L. Murphy"'
Autor:
Roxane Tussiwand, Michael S. Behnke, Nicole M. Kretzer, Gary E. Grajales-Reyes, Theresa L. Murphy, Robert D. Schreiber, Kenneth M. Murphy, L. David Sibley
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Immunity to Toxoplasma gondii at early stages of infection in C57BL/6 mice depends on gamma interferon (IFN-γ) production by NK cells, while at later stages it is primarily mediated by CD8 T cells. We decided to explore the requirement for
Externí odkaz:
https://doaj.org/article/dd378a1387414af696a0707ee5fde62a
Autor:
Carlos G. Briseño, Malay Haldar, Nicole M. Kretzer, Xiaodi Wu, Derek J. Theisen, Wumesh KC, Vivek Durai, Gary E. Grajales-Reyes, Arifumi Iwata, Prachi Bagadia, Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2462-2474 (2016)
Both classical DCs (cDCs) and monocyte-derived DCs (Mo-DCs) are capable of cross-priming CD8+ T cells in response to cell-associated antigens. We found that Ly-6ChiTREML4− monocytes can differentiate into Zbtb46+ Mo-DCs in response to granulocyte-m
Externí odkaz:
https://doaj.org/article/de1a4bee2de24f20a6e0663f97de0bbe
Autor:
Tian-Tian Liu, Feiya Ou, Julia A. Belk, Prachi Bagadia, David A. Anderson, Vivek Durai, Winnie Yao, Ansuman T. Satpathy, Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Genes & Development. 37:291-302
Individual elements within a superenhancer can act in a cooperative or temporal manner, but the underlying mechanisms remain obscure. We recently identified anIrf8superenhancer, within which different elements act at distinct stages of type 1 classic
Autor:
Tian-Tian Liu, Sunkyung Kim, Pritesh Desai, Do-Hyun Kim, Xiao Huang, Stephen T. Ferris, Renee Wu, Feiya Ou, Takeshi Egawa, Steven J. Van Dyken, Michael S. Diamond, Peter F. Johnson, Masato Kubo, Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Nature. 607:142-148
The divergence of the common dendritic cell progenitor
Autor:
Kenneth M. Murphy, Theresa L. Murphy, Robert D. Schreiber, Tian-Tian Liu, Jing Chen, Sunkyung Kim, Xiao Huang, Renee Wu, Feiya Ou, Ray A. Ohara, Stephen T. Ferris
As a cell-based cancer vaccine, dendritic cells (DC), derived from peripheral blood monocytes or bone marrow (BM) treated with GM-CSF (GMDC), were initially thought to induce antitumor immunity by presenting tumor antigens directly to host T cells. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5a2af4ebdac0e4bffa3c57265d0a2e
https://doi.org/10.1158/2326-6066.c.6550934.v1
https://doi.org/10.1158/2326-6066.c.6550934.v1
Autor:
Kenneth M. Murphy, Theresa L. Murphy, Robert D. Schreiber, Tian-Tian Liu, Jing Chen, Sunkyung Kim, Xiao Huang, Renee Wu, Feiya Ou, Ray A. Ohara, Stephen T. Ferris
Supplementary Figure from cDC1 Vaccines Drive Tumor Rejection by Direct Presentation Independently of Host cDC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c7fd5f7a32c9a02b70c0c2fe00c605
https://doi.org/10.1158/2326-6066.22545404
https://doi.org/10.1158/2326-6066.22545404
Autor:
Stephen T. Ferris, Tiantian Liu, Jing Chen, Ray A. Ohara, Feiya Ou, Renee Wu, Sunkyung Kim, Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The events that initiate autoimmune diabetes in nonobese diabetic (NOD) mice remain poorly understood. CD4 + and CD8 + T cells are both required to develop disease, but their relative roles in initiating disease are unclear. To test whether CD4 + T c
Autor:
Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Cellular and Molecular Immunology
The clinical success of immune checkpoint therapy (ICT) has produced explosive growth in tumor immunology research because ICT was discovered through basic studies of immune regulation. Much of the current translational efforts are aimed at enhancing
Autor:
Renee Wu, Ray A. Ohara, Suin Jo, Tian-Tian Liu, Stephen T. Ferris, Feiya Ou, Sunkyung Kim, Derek J. Theisen, David A. Anderson, Brian W. Wong, Timothy Gershon, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Nat Immunol
CD40 signaling in classical type 1 dendritic cells (cDC1s) is required for CD8 T cell-mediated tumor rejection, but the underlying mechanisms are incompletely understood. Here, we identified CD40-induced genes in cDC1s, including Cd70, Tnfsf9, Ptgs2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73098e06eb50c5f3184eb4070018f0b1
https://europepmc.org/articles/PMC9896965/
https://europepmc.org/articles/PMC9896965/
Autor:
Stephen T. Ferris, Jing Chen, Ray A. Ohara, Feiya Ou, Renee Wu, Sunkyung Kim, Tiantian Liu, Theresa L. Murphy, Kenneth M. Murphy
The events that initiate autoimmune diabetes in NOD mice remain poorly understood. CD4 and CD8 T cells are both required but whether either cell initiates disease is unclear. To test whether CD4 T cell infiltration into islet required damage to β ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3ec641d1136b8b78bf1f474a319b78f
https://doi.org/10.1101/2022.09.02.506326
https://doi.org/10.1101/2022.09.02.506326