Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Theresa L. Gerrard"'
Publikováno v:
Generics and Biosimilars Initiative Journal. 4:118-124
Autor:
Theresa L. Gerrard
Publikováno v:
Drug Information Journal. 34:305-309
Although the Food and Drug Administration (FDA) and the pharmaceutical industry share a common goal in bringing safe and effective medicines to the public, each has misunderstandings about the other. Dispelling some of these misunderstandings about e
Publikováno v:
Progress in Growth Factor Research. 5:213-222
This article describes the drug approval process at the Center for Biologics Evaluation and Research (CBER), FDA, for cytokines and growth factors that would be licensed for clinical use in the U.S.A. CBER is responsible for setting policy, providing
Publikováno v:
Journal of Leukocyte Biology. 50:176-181
Macrophages are uniquely responsive to bacterial lipopolysaccharide (LPS) for activation of a number of host defense functions and production of bioactive mediators. One potentially important mediator produced by LPS-stimulated macrophages is interfe
Publikováno v:
Biologicals. 21:77-79
Autor:
Theresa L. Gerrard, Marion Gruber
Publikováno v:
Cellular immunology. 142(2)
Macrophage colony-stimulating factor (M-CSF) stimulates the survival, proliferation, and differentiation of mononuclear phagocytes. In this study, the qualitative and relative quantitative ability of various cytokines to induce and to synergize in M-
Publikováno v:
Journal of Interferon Research. 9:115-124
We have investigated the interaction of interferon-gamma (IFN-gamma) with monocytes or products of stimulated monocytes. We have shown that IFN-gamma does not stimulate IFN-alpha production in monocytes. Staphylococcus aureus (SAC) but not lipopolysa
Autor:
Barton F. Haynes, Louis F. Diehl, John J. Hooks, Anthony S. Fauci, Barbara Detrick-Hooks, Theresa L. Gerrard
Publikováno v:
Blood. 59:198-201
We report a patient with a disease characterized by proliferation of T cells with Fc receptors for IgG (TG). However, unlike lymphoid cells from normal individuals or from patients with other lymphoid malignancies, the patient's lymphocytes spontaneo
Publikováno v:
Cellular Immunology. 84:311-316
Human peripheral blood monocytes incubated overnight with hydrocortisone had an increased expression of HLA-DR antigens. This change was noted as an increased proportion of DR-positive staining monocytes at greater fluorescence intensities as determi
Publikováno v:
International Journal of Cancer. 26:585-593
This study was aimed at characterizing the parameters which regulate human monocyte-mediated cytotoxicity to tumor cells as well as characterizing the target cell specificity, kinetics, etc., of the cytotoxic mechanism. Normal human peripheral blood