Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Theresa J. Berndt"'
Publikováno v:
Bone
Hypophosphatasia (HPP) is the inborn-error-of-metabolism caused by loss-of-function mutation(s) of the ALPL gene that encodes the tissue-nonspecific isoenzyme of alkaline phosphatase (TNSALP). TNSALP in healthy individuals is on cell surfaces richly
Autor:
Theresa J. Berndt, Rajiv Kumar
Publikováno v:
Physiology. 24:17-25
Phosphorus plays a critical role in diverse biological processes, and, therefore, the regulation of phosphorus balance and homeostasis are critical to the well being of the organism. Changes in environmental, dietary, and serum concentrations of inor
Autor:
Stephen J. O'Brien, Theresa J. Berndt, Marlon Pragnell, Beate Lanske, Rajiv Kumar, Theodore A. Craig, Mohammed S. Razzaque, Despina Sitara, Ann E. Bowe, Susan C. Schiavi, Daniel J. McCormick
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 454:615-623
The phosphaturic activity of intact, full-length, fibroblast growth factor-23 (FGF-23) is well documented. FGF-23 circulates as the intact protein, and as fragments generated as the result of proteolysis of the full-length protein. To assess whether
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F1170-F1182
Phosphate ions are critical for normal bone mineralization, and phosphate plays a vital role in a number of other biological processes such as signal transduction, nucleotide metabolism, and enzyme regulation. The study of rare disorders associated w
Autor:
Theresa J. Berndt, Rajesh Kumar
Publikováno v:
BoneKEy-Osteovision. 2:5-16
Autor:
John Vassiliadis, Susan C. Schiavi, Richard Finnegan, Theodore A. Craig, Ann E. Bowe, David Reczek, Theresa J. Berndt, Rajesh Kumar, Suzanne M. Jan de Beur
Publikováno v:
Journal of Clinical Investigation. 112:785-794
Tumors associated with osteomalacia elaborate the novel factor(s), phosphatonin(s), which causes phosphaturia and hypophosphatemia by cAMP-independent pathways. We show that secreted frizzled-related protein-4 (sFRP-4), a protein highly expressed in
Publikováno v:
Journal of the American Society of Nephrology. 13:1449-1454
Renal interstitial hydrostatic pressure (RIHP) is a link between increased arterial BP and natriuresis. The mechanism whereby increases in RIHP inhibits sodium and water transport across the mammalian proximal tubule epithelium may involve changes in
Publikováno v:
American Journal of Physiology-Renal Physiology. 282:F821-F825
During normal pregnancy, a gradual plasma volume expansion (VE) occurs and reaches a maximum level at late term. Pressure natriuresis and renal interstitial hydrostatic pressure (RIHP) responses are attenuated in pregnant rats. Also, basal RIHP is lo
Publikováno v:
Life Sciences. 69:1123-1131
The objective of this study was to determine the effect of N(G)-monomethyl-L-arginine (L-NMMA) infusion on plasma renin activity (PRA) in the presence or absence of the renal nerves in normotensive Wistar-Kyoto (WKY) rats and Okamoto spontaneously hy
Autor:
Yongqing Wang, Franklyn G. Knox, Jennifer M. Gross, Theresa J. Berndt, Michael A. Peterson, Mathew J. So
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 280:R248-R254
The purpose of the present investigation was to study the effects of inhibition of monoamine oxidase (MAO) and/or catechol- O-methyltransferase (COMT), enzymes involved in the degradation of dopamine (DA) and serotonin (5-HT), on intrarenal DA and 5-