Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Theresa I, Medrano"'
Autor:
Ana M. Mesa, Theresa I. Medrano, Vijay K. Sirohi, William H. Walker, Richard D. Johnson, Sergei G. Tevosian, Angie M. Adkin, Paul S. Cooke
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 616-629 (2022)
Brown adipose tissue (BAT) generates heat through non-shivering thermogenesis, and increasing BAT amounts or activity could facilitate obesity treatment and provide metabolic benefits. In mice, BAT has been reported in perirenal, thoracic and cranial
Externí odkaz:
https://doaj.org/article/1494595abbc045c4983e205567fa95d4
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107028- (2023)
Summary: Maternal uterine remodeling facilitates embryo implantation, stromal cell decidualization and placentation, and perturbation of these processes may cause pregnancy loss. Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that
Externí odkaz:
https://doaj.org/article/e60d505507c644da9f0181cba3e94e6b
Publikováno v:
Epigenomes, Vol 4, Iss 3, p 20 (2020)
Epigenetic modifications regulate normal physiological, as well as pathological processes in various organs, including the uterus and placenta. Both organs undergo dramatic and rapid restructuring that depends upon precise orchestration of events. Ep
Externí odkaz:
https://doaj.org/article/95c99fe9cd0c44bfbe2573543390205c
Publikováno v:
Asian Journal of Andrology, Vol 17, Iss 3, Pp 355-359 (2015)
There have been significant breakthroughs over the past decade in the development and use of pluripotent stem cells as a potential source of cells for applications in regenerative medicine. It is likely that this methodology will begin to play an imp
Externí odkaz:
https://doaj.org/article/f6d9a245683248e58bf421b2b879ce2a
Autor:
Ana M Mesa, Theresa I. Medrano, Geetu Tuteja, Jiude Mao, Nathan J. Bivens, Paul S. Cooke, Alexander Jurkevich, Cheryl S. Rosenfeld
Publikováno v:
Biol Reprod
Histone proteins undergo various modifications that alter chromatin structure, including addition of methyl groups. Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that methylates lysine residue 27, and thereby suppresses gene expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6fdaf4cc905231629551e644a02c6c
https://doi.org/10.1093/biolre/ioab147
https://doi.org/10.1093/biolre/ioab147
Autor:
Duolin Wang, Manjunatha K. Nanjappa, Jiude Mao, Paul S. Cooke, Theresa I. Medrano, Jessica A. Kinkade, Yang Liu, Zhen Lyu, Trupti Joshi, Cheryl S. Rosenfeld, Sergei G. Tevosian, Fahong Yu, Ana M Mesa
Publikováno v:
Physiol Genomics
Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of luminal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da6a18c7032c2940d963bedc0aa86a5
https://doi.org/10.1152/physiolgenomics.00098.2019
https://doi.org/10.1152/physiolgenomics.00098.2019
Autor:
Vijay K. Sirohi, Athilakshmi Kannan, Paul S. Cooke, Theresa I. Medrano, Indrani C. Bagchi, Ana M Mesa
Publikováno v:
Endocrinology
17β-estradiol (E2) treatment of ovariectomized adult mice stimulates the uterine PI3K-AKT signaling pathway and epithelial proliferation through estrogen receptor 1 (ESR1). However, epithelial proliferation occurs independently of E2/ESR1 signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d858f7d14c08e85a2eecb9bd5d39d8
https://doi.org/10.1210/endocr/bqab233
https://doi.org/10.1210/endocr/bqab233
Autor:
Ellis R. Levin, Theresa I. Medrano, Jiude Mao, Paul S. Cooke, Cheryl S. Rosenfeld, Paul D. Caldo, Ana M Mesa, Madison T. Ortega, Manjunatha K. Nanjappa, Jessica A. Kinkade
Publikováno v:
Biol Reprod
Biology of reproduction, vol 101, iss 2
Biology of reproduction, vol 101, iss 2
Both membrane and nuclear fractions of estrogen receptor 1 (ESR1) mediate 17β-estradiol (E2) actions. Mice expressing nuclear (n)ESR1 but lacking membrane (m)ESR1 (nuclear-only estrogen receptor 1 [NOER] mice) show reduced E2 responsivity and reprod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acb6281ba6c9d53b4e0efa8b51a10f4
https://doi.org/10.1093/biolre/ioz090
https://doi.org/10.1093/biolre/ioz090
Publikováno v:
Epigenomes, Vol 4, Iss 20, p 20 (2020)
Epigenomes
Epigenomes
Epigenetic modifications regulate normal physiological, as well as pathological processes in various organs, including the uterus and placenta. Both organs undergo dramatic and rapid restructuring that depends upon precise orchestration of events. Ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ed334a6e3030c506af0a072214a77e
https://www.mdpi.com/2075-4655/4/3/20
https://www.mdpi.com/2075-4655/4/3/20
Autor:
Gail S. Prins, Manjunatha K. Nanjappa, Theresa I. Medrano, Paul S. Cooke, Barry R. Zirkin, Haolin Chen
Publikováno v:
Andrology. 5:1165-1173
Summary Stem Leydig cells (SLCs), precursors of testicular Leydig cells that secrete testosterone required for male sexual differentiation, spermatogenesis, and fertility, were recently identified in rat testes. Various types of stem cells have shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5085c8c73154345536b6138b374c9d5f
https://doi.org/10.1111/andr.12415
https://doi.org/10.1111/andr.12415