Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Theresa H Ward"'
Autor:
Emmanuel C Patin, Anna C Geffken, Sam Willcocks, Christoph Leschczyk, Albert Haas, Falk Nimmerjahn, Roland Lang, Theresa H Ward, Ulrich E Schaible
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174973 (2017)
The causative agent of tuberculosis, Mycobacterium tuberculosis (M. tuberculosis), contains an abundant cell wall glycolipid and a crucial virulence factor, trehalose-6,6'-dimycolate (TDM). TDM causes delay of phagosome maturation and thus promotes s
Externí odkaz:
https://doaj.org/article/65dbcb618d934ee5958e9ff1253730e3
Autor:
Alex P McLatchie, Hollie Burrell-Saward, Elmarie Myburgh, Michael D Lewis, Theresa H Ward, Jeremy C Mottram, Simon L Croft, John M Kelly, Martin C Taylor
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 11, p e2571 (2013)
Human African trypanosomiasis is caused by infection with parasites of the Trypanosoma brucei species complex, and threatens over 70 million people in sub-Saharan Africa. Development of new drugs is hampered by the limitations of current rodent model
Externí odkaz:
https://doaj.org/article/89956e7587f44366b48ce7e39be94ae3
Autor:
Holger W Auner, Anne Marie Moody, Theresa H Ward, Marianne Kraus, Enrico Milan, Philippa May, Aristeidis Chaidos, Christoph Driessen, Simone Cenci, Francesco Dazzi, Amin Rahemtulla, Jane F Apperley, Anastasios Karadimitris, Niall Dillon
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74415 (2013)
Inhibition of the proteasome is a widely used strategy for treating multiple myeloma that takes advantage of the heavy secretory load that multiple myeloma cells (MMCs) have to deal with. Resistance of MMCs to proteasome inhibition has been linked to
Externí odkaz:
https://doaj.org/article/2cb4cbe12a5640ff82e1112823c62e28
Autor:
Nuria Andreu, Andrea Zelmer, Taryn Fletcher, Paul T Elkington, Theresa H Ward, Jorge Ripoll, Tanya Parish, Gregory J Bancroft, Ulrich Schaible, Brian D Robertson, Siouxsie Wiles
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10777 (2010)
Mycobacterium tuberculosis, the causative agent of tuberculosis, still represents a major public health threat in many countries. Bioluminescence, the production of light by luciferase-catalyzed reactions, is a versatile reporter technology with mult
Externí odkaz:
https://doaj.org/article/fd1d49049ccc428898603c2b2218c112
Autor:
Paul Carroll, Lise J Schreuder, Julian Muwanguzi-Karugaba, Siouxsie Wiles, Brian D Robertson, Jorge Ripoll, Theresa H Ward, Gregory J Bancroft, Ulrich E Schaible, Tanya Parish
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9823 (2010)
Fluorescent reporter proteins have proven useful for imaging techniques in many organisms. We constructed optimized expression systems for several fluorescent proteins from the far-red region of the spectrum and analyzed their utility in several myco
Externí odkaz:
https://doaj.org/article/b98a8fadeb954dadb622625d8ceac079
Autor:
Kenneth Ssebambulidde, Anthony Kayiira, Ivan Segawa, Sylvia Namanda, Victoria Nakibuuka, Victor Musiime, Theresa H. Ward
Publikováno v:
BMC pediatrics. 22(1)
Background Many aspects of microbial dissemination appear to vary with host cholesterol levels. Since neonatal septicemia remains a leading cause of newborn admissions and mortality in resource-limited settings, the contribution of abnormal cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2c98eccf35ace171a57309686b660e
https://pubmed.ncbi.nlm.nih.gov/35858938
https://pubmed.ncbi.nlm.nih.gov/35858938
Publikováno v:
Traffic. 18:733-746
Eukaryotic cells utilize multiple endocytic pathways for specific uptake of ligands or molecules, and these pathways are commonly hijacked by pathogens to enable host cell invasion. Escherichia coli K1, a pathogenic bacterium that causes neonatal men
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6970a0d153572e1a23a84c90b79bfc6c
https://doi.org/10.1111/tra.12508
https://doi.org/10.1111/tra.12508
Autor:
Martin C. Taylor, Theresa H. Ward
Publikováno v:
Methods (San Diego, Calif.). 127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af5c79335ba88bc3e7dac83cdea11c5
https://pubmed.ncbi.nlm.nih.gov/28867066
https://pubmed.ncbi.nlm.nih.gov/28867066
Autor:
Simon L. Croft, Hollie Burrell-Saward, Mo Alavijeh, Andy Harris, Hatem Sallam, Theresa H. Ward, Raul de LaFlor
Human African trypanosomiasis (HAT) is a neglected tropical disease, with a population of 70 million at risk. Current treatment options are limited. In the search for new therapeutics, the repurposing of the broad-spectrum antiprotozoal drug fexinida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335d388339df1f34aa3e2b2a970cd81f
Autor:
Mark P. Mattson, James Q. Wang, David G. Le Couteur, Sarah J. Mitchell, Alessandra Warren, Theresa H. Ward, Vilhelm A. Bohr, Rafael de Cabo, Linda H. Bergersen, Nagendra Singh, Christopher A. Dunn, Aswin Mangerich, Victoria C. Cogger, Mahdi Hasan-Olive, Teruaki Iyama, Evandro Fei Fang, Mark A. Wilson, Sebastian Veith, Ruin Moaddel, Morten Scheibye-Knudsen, David M. Wilson, Deborah L. Croteau
Publikováno v:
Cell Metabolism. 20:840-855
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in genes encoding the DNA repair proteins CS group A or B (CSA or CSB). Since dietary interventions can alter neurodegenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88135a562724194e9c4771019b3d942
https://doi.org/10.1016/j.cmet.2014.10.005
https://doi.org/10.1016/j.cmet.2014.10.005