Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Theresa Hörmann"'
Autor:
Anthony Grelier, Matej Zadravec, Johan Remmelgas, Thomas Forgber, Franco Colacino, Gabrielle Pilcer, Fanny Stauffer, Theresa Hörmann-Kincses
Publikováno v:
Pharmaceutical Research. 39:2005-2016
With an increased adoption of continuous manufacturing for pharmaceutical production, the ConsiGma® CTL25 wet granulation and tableting line has reached widespread use. In addition to the continuous granulation step, the semi-continuous six-segmente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfa1b56d15cc669fff276e374772e32
https://doi.org/10.1007/s11095-022-03361-4
https://doi.org/10.1007/s11095-022-03361-4
Autor:
Theresa Hörmann, Adrian Funke, Reinhardt-Karsten Mürb, Johannes Khinast, Amrit Paudel, Nina Jäger
Publikováno v:
International Journal of Pharmaceutics. 553:408-421
This work evaluates several compositions of an amorphous solid dispersion (ASD) comprising nimodipine (NMD) as poorly soluble model API in a dual-polymer carrier system. HPMC E5 and Eudragit E were used for the two polymeric carriers. The formulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9675bc9bb232d90d0ff5e685bd37af5
https://doi.org/10.1016/j.ijpharm.2018.10.035
https://doi.org/10.1016/j.ijpharm.2018.10.035
Autor:
Wen Kai Hsiao, Jakob Rehrl, Johannes Khinast, Theresa Hörmann-Kincses, Rok Sibanc, Meik Bernhard Franke
Publikováno v:
International journal of pharmaceutics, 607:121041. Elsevier
Wet granulation lines in pharmaceutical manufacturing facilities typically comprise a dryer that removes the excess moisture content after wet granulation. In this study, a semi-continuous dryer installed in the ConsiGma 25 wet granulation line was i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52f6630731df3207ae22715c23ae01b
https://doi.org/10.1016/j.ijpharm.2021.121041
https://doi.org/10.1016/j.ijpharm.2021.121041
Autor:
Peter Toson, Theresa Hörmann, Patrizia Ghiotti, Olaf Behrend, Satu Lakio, Wen-Kai Hsiao, Reto Maurer, Johannes Khinast, F. Stauffer, Amrit Paudel, Finn Bauer, James Holman
Publikováno v:
Drug discovery today. 25(4)
The pharmaceutical industry today is experiencing a paradigm shift from batch to continuous manufacturing, which promises greater flexibility to target diverse populations, as well as more-consistent product quality to ensure best efficacy. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e01fb3eb37d907d72dd7e38588680ba
https://pubmed.ncbi.nlm.nih.gov/31982395
https://pubmed.ncbi.nlm.nih.gov/31982395
Autor:
Theresa Hörmann, Sebastian Soritz, Manuel C. Maier, Carina Dertnig, Bianca Grabner, Katharina Hiebler, Heidrun Gruber-Woelfler
Publikováno v:
Journal of Flow Chemistry
The active pharmaceutical ingredient sacubitril acts as a neprilysin inhibitor in the body and is administered to patients suffering from high blood pressure and chronic heart failure. In this paper, we report the development of a three-step setup fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837ac3fe7f4c8fe72c7a8c02d87ddbbc
Autor:
Fien De Leersnyder, Anssi Pekka Karttunen, Thomas De Beer, Jarkko Ketolainen, Ossi Korhonen, Theresa Hörmann, Wen Kai Hsiao
Publikováno v:
International journal of pharmaceutics. 563
Over the recent decade, benefits of continuous manufacturing (CM) of pharmaceutical products have been acknowledged widely. In contrast to batch processes, the product is not physically separated into batches in CM, which creates a few challenges. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b623a5aab4975e02a4b30b08d883b5e8
https://pubmed.ncbi.nlm.nih.gov/30930190
https://pubmed.ncbi.nlm.nih.gov/30930190
Autor:
Ossi Korhonen, Thomas De Beer, Anssi-Pekka Karttunen, Ingmar Nopens, Niels Nicolaï, Theresa Hörmann, Jakob Rehrl, Johannes Khinast, Martin Horn
Publikováno v:
International journal of pharmaceutics. 543(1-2)
One major advantage of continuous pharmaceutical manufacturing over traditional batch manufacturing is the possibility of enhanced in-process control, reducing out-of-specification and waste material by appropriate discharge strategies. The decision
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5915358fee6c2a327f4263b31ec573
https://pubmed.ncbi.nlm.nih.gov/29555436
https://pubmed.ncbi.nlm.nih.gov/29555436
Autor:
Andreas Witschnigg, Gerold Koscher, Stephan Laske, Theresa Hörmann, Johannes Khinast, Patrick Wahl, Wen Kai Hsiao
Publikováno v:
Continuous Manufacturing of Pharmaceuticals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1908667baf5ef94c8cbe21977261c27a
https://doi.org/10.1002/9781119001348.ch10
https://doi.org/10.1002/9781119001348.ch10
Autor:
Patrick Wahl, Ian C. Jones, Theresa Hörmann, Reinhardt-Karsten Mürb, Johannes Khinast, Daniel Markl, Daniel Franz Treffer, Eva Roblegg, Simone Schrank, Paul Cruise, Gerold Koscher
Publikováno v:
International journal of pharmaceutics. 466(1-2)
This work focuses on the implementation and application of an in-line particle measurement tool to monitor particle properties of hot-melt extruded pellets. A novel image analysis system (Eyecon) is used to analyze pellets with a size of approximatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1b32615718ed4b1880ce0831eaf78c
https://pubmed.ncbi.nlm.nih.gov/24614578
https://pubmed.ncbi.nlm.nih.gov/24614578