Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Theresa Grohmann"'
Autor:
Antje Garten, Theresa Grohmann, Katarina Kluckova, Gareth G. Lavery, Wieland Kiess, Melanie Penke
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 4048 (2019)
Sorafenib is a multi-kinase inhibitor and one of the few systemic treatment options for patients with advanced hepatocellular carcinomas (HCCs). Resistance to sorafenib develops frequently and could be mediated by the nicotinamide adenine dinucleotid
Externí odkaz:
https://doaj.org/article/0539cba4290643eab2da3c438b4d51e9
Autor:
Stefanie Petzold-Quinque, Sandy Richter, Wieland Kiess, Susanne Schuster, Theresa Grohmann, Melanie Penke, Antje Garten
Publikováno v:
Leukemia research. 69
NAMPT (Nicotinamide phosphoribosyltransferase) catalyses the rate-limiting step in the NAD biosynthesis from nicotinamide and thereby regulates the activity of NAD-dependent enzymes. Cancer cells are highly dependent on NAD for energy and DNA repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d6cf56580e0162c15db537e82e4aa3
https://pubmed.ncbi.nlm.nih.gov/29653431
https://pubmed.ncbi.nlm.nih.gov/29653431