Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Theresa Frank"'
Autor:
Theresa Frank, Jens Neumann, Anne Assmann, Stefanie Schreiber, Aiden Haghikia, Maria Barleben, Michael Sailer, Michael Goertler
Publikováno v:
Cerebrovascular Diseases Extra, Vol 14, Iss 1, Pp 21-29 (2024)
Introduction: Non-adherence to recommended secondary preventive anticoagulation in stroke patients with atrial fibrillation (AF) is a common phenomenon, although the introduction of direct oral anticoagulants (DOACs) has simplified anticoagulation ma
Externí odkaz:
https://doaj.org/article/c4ccd5c679d9480aaae64b73f51adc8e
Publikováno v:
Medical microbiology and immunology. 208(3-4)
Cytomegaloviruses (CMVs) have developed multiple diverse strategies to ensure their replicative success and to evade immune recognition. Given the fact that G protein-coupled receptors (GPCRs) are key regulators of numerous cellular processes and mod
Autor:
Ralf Palmisano, Mette M. Rosenkilde, Regine Brox, Olav Larsen, Lampros Milanos, Theresa Frank, Jürgen Einsiedel, Gašper Poklukar, Maximilian Dürr, Nuska Tschammer, Reiner Waibel, Ivana Ivanović-Burmazović, Gertrud Malene Hjortø
Publikováno v:
Journal of Medicinal Chemistry. 59:2222-2243
In this work we report a design, synthesis, and detailed functional characterization of unique strongly biased allosteric agonists of CXCR3 that contain tetrahydroisoquinoline carboxamide cores. Compound 11 (FAUC1036) is the first strongly biased all
Insight into structural requirements for selective and/or dual CXCR3 and CXCR4 allosteric modulators
Autor:
Marko Anderluh, Regine Brox, Tihomir Tomašič, Urban Švajger, Nuska Tschammer, Nikola Minovski, Anja Kolarič, Theresa Frank
Publikováno v:
European journal of medicinal chemistry, str. 68-90 : Ilustr., Vol. 154, June 2018
COBISS-ID: 25429760
COBISS-ID: 25429760
Based on the previously published pyrazolopyridine-based hit compound for which negative allosteric modulation of both CXCR3 and CXCR4 receptors was disclosed, we designed, synthesized and biologically evaluated a set of novel, not only negative, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f30de42121a8c2d6882591ea86a195
https://www.sciencedirect.com/science/article/pii/S0223523418304173
https://www.sciencedirect.com/science/article/pii/S0223523418304173
Autor:
Stephan Kohrt, Tony Fröhlich, Manfred Marschall, Theresa Frank, Svetlana B. Tsogoeva, Friedrich Hahn, Luca D. Bertzbach, Thomas Stamminger, Benedikt B. Kaufer
Publikováno v:
Antiviral research. 152
Human cytomegalovirus (HCMV) is a major human pathogen and is associated with severe pathology, such as life-threatening courses of infection in immunocompromised individuals and neonates. Currently, antiviral therapy is still hampered by a considera
Publikováno v:
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, Vol 31, Iss 1 (2022)
Real-world laboratories are receiving increasing public attention and have established themselves as a relevant research format in technology assessment. They appear particularly suited to address current challenges through social learning. However,
Externí odkaz:
https://doaj.org/article/674a259fa8c8492f87d312e2d2355578