Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Theresa E, Hickey"'
Autor:
Dharmesh D. Bhuva, Chin Wee Tan, Agus Salim, Claire Marceaux, Marie A. Pickering, Jinjin Chen, Malvika Kharbanda, Xinyi Jin, Ning Liu, Kristen Feher, Givanna Putri, Wayne D. Tilley, Theresa E. Hickey, Marie-Liesse Asselin-Labat, Belinda Phipson, Melissa J. Davis
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Spatial molecular data has transformed the study of disease microenvironments, though, larger datasets pose an analytics challenge prompting the direct adoption of single-cell RNA-sequencing tools including normalization methods. Here, we de
Externí odkaz:
https://doaj.org/article/b13da81ba36848aea93f840263cbb1cf
Autor:
Leila Hosseinzadeh, Zoya Kikhtyak, Geraldine Laven-Law, Stephen M. Pederson, Caroline G. Puiu, Clive S. D’Santos, Elgene Lim, Jason S. Carroll, Wayne D. Tilley, Amy R. Dwyer, Theresa E. Hickey
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Background The androgen receptor (AR) is a tumor suppressor in estrogen receptor (ER) positive breast cancer, a role sustained in some ER negative breast cancers. Key factors dictating AR genomic activity in a breast context are largely unkn
Externí odkaz:
https://doaj.org/article/d7b51d564a0b4733aace68da8648cf13
Autor:
Allegra Freelander, Geraldine laven-Law, Leila Eshraghi, Nimmy Geetha, Peta Somerville, Marie Pickering, Sarah Alexandrou, C. Elizabeth Caldon, Wayne D. Tilley, Theresa E. Hickey, Elgene Lim
Publikováno v:
Cancer Research. 83:P4-08
Background: The Androgen Receptor (AR) is expressed in up to 90% of all ER+ breast cancers and has been associated with better patient outcome. While androgens were used at a high dose as an anticancer therapy historically, this was discontinued with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feab2bf5e87844a2ab92b82784593a70
https://doi.org/10.1158/1538-7445.sabcs22-p4-08-16
https://doi.org/10.1158/1538-7445.sabcs22-p4-08-16
Autor:
Xuan Huang, Gina Reye, Konstantin I. Momot, Tony Blick, Thomas Lloyd, Wayne D. Tilley, Theresa E. Hickey, Cameron E. Snell, Rachel K. Okolicsanyi, Larisa M. Haupt, Vito Ferro, Erik W. Thompson, Honor J. Hugo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/a0c13bb93e554fb7b5f4819b491b5e11
Autor:
Xuan Huang, Gina Reye, Konstantin I. Momot, Tony Blick, Thomas Lloyd, Wayne D. Tilley, Theresa E. Hickey, Cameron E. Snell, Rachel K. Okolicsanyi, Larisa M. Haupt, Vito Ferro, Erik W. Thompson, Honor J. Hugo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mammographic density (MD) is a strong and independent factor for breast cancer (BC) risk and is increasingly associated with BC progression. We have previously shown in mice that high MD, which is characterized by the preponderance of a fibrous strom
Externí odkaz:
https://doaj.org/article/2f289aa0db814ff1b2c8320fff987b1e
Autor:
Margaret M. Centenera, Theresa E. Hickey, Shalini Jindal, Natalie K. Ryan, Preethi Ravindranathan, Hisham Mohammed, Jessica L. Robinson, Matthew J. Schiewer, Shihong Ma, Payal Kapur, Peter D. Sutherland, Clive E. Hoffmann, Claus G. Roehrborn, Leonard G. Gomella, Jason S. Carroll, Stephen N. Birrell, Karen E. Knudsen, Ganesh V. Raj, Lisa M. Butler, Wayne D. Tilley
Publikováno v:
Molecular Oncology, Vol 12, Iss 9, Pp 1608-1622 (2018)
Breast and prostate cancer research to date has largely been predicated on the use of cell lines in vitro or in vivo. These limitations have led to the development of more clinically relevant models, such as organoids or murine xenografts that utiliz
Externí odkaz:
https://doaj.org/article/0552f838da6a4c13b4e0ce9e34c20273
Autor:
Theresa E. Hickey, Peter I. Mackenzie, Wayne D. Tilley, Jason S. Carroll, Jessica L.L. Robinson, Carlos Caldas, Roslin Russell, Apichaya Chanawong, Dhilushi Wijayakumara, Robyn Meech, Gerard A. Tarulli, Luke A. Selth, Dong G. Hu
Word Document with legends for supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230371ea6aaaa4e1ade5b8023763b789
https://doi.org/10.1158/0008-5472.22412508
https://doi.org/10.1158/0008-5472.22412508
Autor:
Theresa E. Hickey, Peter I. Mackenzie, Wayne D. Tilley, Jason S. Carroll, Jessica L.L. Robinson, Carlos Caldas, Roslin Russell, Apichaya Chanawong, Dhilushi Wijayakumara, Robyn Meech, Gerard A. Tarulli, Luke A. Selth, Dong G. Hu
Glucuronidation is an enzymatic process that terminally inactivates steroid hormones, including estrogens and androgens, thereby influencing carcinogenesis in hormone-dependent cancers. While estrogens drive breast carcinogenesis via the estrogen rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a48b384e41efde1421cf1df308c5db2
https://doi.org/10.1158/0008-5472.c.6508455
https://doi.org/10.1158/0008-5472.c.6508455
Autor:
Wayne D. Tilley, Theresa E. Hickey, Carlo Palmieri, Robert L. Sutherland, Stephen N. Birrell, David G. Huntsman, Sarah L. Vowler, Alexandra I. Ruiz, Andrew J. Sakko, Ewan K.A. Millar, Esmaeil Ebrahimie, Sandra A. O'Toole, Catriona M. McNeil, Samuel Leung, Lisa M. Butler, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Purpose: Consensus is lacking regarding the androgen receptor (AR) as a prognostic marker in breast cancer. The objectives of this study were to comprehensively review the literature on AR prognostication and determine optimal criteria for AR as an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab858ec386aa4731623a65732a1881c8
https://doi.org/10.1158/1078-0432.c.6526020.v1
https://doi.org/10.1158/1078-0432.c.6526020.v1
Autor:
Wayne D. Tilley, Theresa E. Hickey, Carlo Palmieri, Robert L. Sutherland, Stephen N. Birrell, David G. Huntsman, Sarah L. Vowler, Alexandra I. Ruiz, Andrew J. Sakko, Ewan K.A. Millar, Esmaeil Ebrahimie, Sandra A. O'Toole, Catriona M. McNeil, Samuel Leung, Lisa M. Butler, Shalini Jindal, Tina Bianco-Miotto, Carmela Ricciardelli
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134a8376bd734fdec422b72fe11248c3
https://doi.org/10.1158/1078-0432.22465434.v1
https://doi.org/10.1158/1078-0432.22465434.v1