Zobrazeno 1 - 10
of 829
pro vyhledávání: '"Theresa A. Whiteside"'
Autor:
Kevin Quann, Konstantinos Lontos, Alison Sehgal, Anastasios Raptis, Annie Im, Robert L. Redner, Kathleen A. Dorritie, Mounzer Agha, Jing-Zhou Hou, Rafic Farah, James Rossetti, Daniel P. Normolle, Theresa L. Whiteside, Yen-Michael Sheng Hsu, Michael Boyiadzis
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/1352c6751639460db757ad5297580943
Publikováno v:
Viruses, Vol 16, Iss 8, p 1291 (2024)
Small extracellular vesicles (sEV) are small membrane-bound nanovesicles with a size range below 200 nm that are released by all types of cells. sEV carry a diverse cargo of proteins, lipids, glycans, and nucleic acids that mimic the content of produ
Externí odkaz:
https://doaj.org/article/fcc58c3266304df4a5bebaa9fbfab087
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Small extracellular vesicles (sEV) in TNBC patients’ plasma promote T cell dysfunction and tumor progression. Here we show that tumor cell-derived exosomes (TEX) carrying surface PDL-1, PD-1, Fas, FasL, TRAIL, CTLA-4 and TGF-β1 induce apo
Externí odkaz:
https://doaj.org/article/a2e18dac29f449d7b806c6d614fff023
Autor:
Michael Boyiadzis, Chang-Sook Hong, Saigopalakrishna Yerneni, Annie Im, Brenda Diergaarde, Theresa L. Whiteside
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3236 (2023)
The small extracellular vesicles (sEV) accumulating in acute myeloid leukemia (AML) patients’ plasma are mixtures of vesicles produced by leukemic and non-malignant cells. sEV originating from leukemia blasts could serve as potential non-invasive b
Externí odkaz:
https://doaj.org/article/f4325404a7714cd5a1fcb7520afdebdc
Autor:
Linda Hofmann, Malgorzata Harasymczuk, Diana Huber, Miroslaw J. Szczepanski, Grzegorz Dworacki, Theresa L. Whiteside, Marie-Nicole Theodoraki
Publikováno v:
Cancers, Vol 15, Iss 22, p 5449 (2023)
Immunoregulatory Arginase-1 (Arg-1) is present in the tumor microenvironment of solid tumors. Its association to clinicopathology and its prognostic impact are inconsistent among different tumor types and biological fluids. This study evaluated Arg-1
Externí odkaz:
https://doaj.org/article/4c742fb415a2458d90159235c3300357
Autor:
Ruijia Liu, Jun Wang, Yang Chen, Jenelle M. Collier, Okan Capuk, Shijie Jin, Ming Sun, Sujan K. Mondal, Theresa L. Whiteside, Donna B. Stolz, Yongjie Yang, Gulnaz Begum
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-15 (2022)
Abstract Reactive astrocytes (RA) secrete lipocalin-2 (LCN2) glycoprotein that regulates diverse cellular processes including cell death/survival, inflammation, iron delivery and cell differentiation. Elevated levels of LCN2 are considered as a bioma
Externí odkaz:
https://doaj.org/article/0489d8d66ecf4686b9e715a3457cb85b
Autor:
Theresa L. Whiteside
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Tumor-derived exosomes (TEX) are a subset of small extracellular vesicles (sEV) present in all body fluids of patients with cancer. In plasma of patients with metastatic melanoma, numbers of exosomes produced by melanoma cells called MTEX are elevate
Externí odkaz:
https://doaj.org/article/dde21f463edb46d6a2f8ec93c3428f4f
Autor:
Nils Ludwig, Saigopalakrishna S. Yerneni, Juliana H. Azambuja, Monika Pietrowska, Piotr Widłak, Cynthia S. Hinck, Alicja Głuszko, Mirosław J. Szczepański, Teresa Kärmer, Isabella Kallinger, Daniela Schulz, Richard J. Bauer, Gerrit Spanier, Steffen Spoerl, Johannes K. Meier, Tobias Ettl, Beatrice M. Razzo, Torsten E. Reichert, Andrew P. Hinck, Theresa L. Whiteside
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 12, Pp n/a-n/a (2022)
Abstract Transforming growth factor β (TGFβ) is a major component of tumor‐derived small extracellular vesicles (TEX) in cancer patients. Mechanisms utilized by TGFβ+ TEX to promote tumor growth and pro‐tumor activities in the tumor microenvir
Externí odkaz:
https://doaj.org/article/f088f547bd094054be588feb402afff5
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12513 (2022)
Exosomes mediate intercellular communication, shuttling messages between cells and tissues. We explored whether exosome tissue sequestration is determined by the exosomes or the tissues using ten radiolabeled exosomes from human or murine, cancerous
Externí odkaz:
https://doaj.org/article/4d06f1c47c3c40cea6e9b737947f556c
Autor:
Saigopalakrishna S. Yerneni, Sarah Werner, Juliana H. Azambuja, Nils Ludwig, Rory Eutsey, Surya D. Aggarwal, Peter C. Lucas, Nathanael Bailey, Theresa L. Whiteside, Phil G. Campbell, N. Luisa Hiller
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Extracellular vesicles (EVs) have recently garnered attention for their participation in host-microbe interactions in pneumococcal infections. However, the effect of EVs on the host immune system remain poorly understood. Our studies focus o
Externí odkaz:
https://doaj.org/article/daf0bbbac4384c3cb6fb8c58d8262fcc