Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Theresa A. Good"'
Publikováno v:
ACS Omega, Vol 5, Iss 32, Pp 20250-20260 (2020)
Externí odkaz:
https://doaj.org/article/3660c1a0a87148a7ac3f4d6f5577b5e9
Publikováno v:
ACS Omega, Vol 5, Iss 32, Pp 20250-20260 (2020)
ACS Omega
ACS Omega
The physiochemical properties of hydrogels utilized in 3D culture can be used to modulate cell phenotype and morphology with a striking resemblance to cellular processes that occur in vivo. Indeed, research areas including regenerative medicine, tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f65abe01f8f56a52bb1c1b04f7041b9
https://doaj.org/article/3660c1a0a87148a7ac3f4d6f5577b5e9
https://doaj.org/article/3660c1a0a87148a7ac3f4d6f5577b5e9
Publikováno v:
Acta Biomaterialia. 112:164-173
Alzheimer's disease (AD) is the most common form of dementia and is associated with the accumulation of amyloid-β (Aβ), a peptide whose aggregation has been associated with neurotoxicity. Drugs targeting Aβ have shown great promise in 2D in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7929c6c7173d3f91d632840df5aad0
https://doi.org/10.1016/j.actbio.2020.05.030
https://doi.org/10.1016/j.actbio.2020.05.030
Publikováno v:
Biotechnol Adv
In the biological milieu of a cell, soluble crowding molecules and rigid confined environments strongly influence whether the protein is properly folded, intrinsically disordered proteins assemble into distinct phases, or a denatured or aggregated pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae858de27efb6818fda7419c134987d
https://pubmed.ncbi.nlm.nih.gov/32512220
https://pubmed.ncbi.nlm.nih.gov/32512220
Publikováno v:
SSRN Electronic Journal.
Alzheimer's disease (AD) is the most common form of dementia and is associated with the accumulation of amyloid-β (Aβ), a peptide whose aggregation has been associated with neurotoxicity. Drugs targeting Aβ have shown great promise in 2D in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b644030b9d79d1e0436e3d761a3fc8a1
https://doi.org/10.2139/ssrn.3423492
https://doi.org/10.2139/ssrn.3423492
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:3255-3262
Reactive oxygen species (ROS), a product of many cellular functions, has been implicated in many age-related pathophysiological processes, including cardiovascular disease. The arterial proteins collagen and elastin may also undergo structural and fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a84c284b0b4722a1d1eafdaf8936bf5
https://doi.org/10.1002/jbm.a.34998
https://doi.org/10.1002/jbm.a.34998
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:2565-2572
Like engineered materials, an artery's biomechanical behavior and function depend on its microstructure. Glycation is associated with both normal aging and diabetes and has been shown to increase arterial stiffness. In this study we examined the dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f646728edf8c138ef568f853fb242a77
https://doi.org/10.1002/jbm.a.34927
https://doi.org/10.1002/jbm.a.34927
Publikováno v:
Protein Science. 19:2291-2304
The accumulation of aggregated β-Amyloid (Aβ) in the brain is a hallmark of Alzheimer's disease and is thought to play a role in the neurotoxicity associated with the disease. The mechanism by which Aβ aggregates induce toxicity is uncertain. None
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da998fac66075dbf72a47eebdb22489
https://doi.org/10.1002/pro.509
https://doi.org/10.1002/pro.509
Publikováno v:
Biotechnology and Bioengineering. 104:181-192
Beta-amyloid peptide (Abeta) is the major protein constituent found in senile plaques in Alzheimer's disease (AD). It is believed that Abeta plays a role in neurodegeneration associated with AD and that its toxicity is related to its structure or agg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf61ce046c27686049fe5c95427ddd3
https://doi.org/10.1002/bit.22367
https://doi.org/10.1002/bit.22367
Publikováno v:
Journal of Theoretical Biology. 258:189-197
beta-Amyloid peptide (A beta), the primary protein component in senile plaques associated with Alzheimer's disease (AD), has been implicated in neurotoxicity associated with AD. Previous studies have shown that the A beta-neuronal membrane interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6714f9146914ae21c1599e591d4eca6e
https://doi.org/10.1016/j.jtbi.2009.02.003
https://doi.org/10.1016/j.jtbi.2009.02.003