Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Theresa A Laguna"'
Autor:
John B O'Connor, Madison M Mottlowitz, Brandie D Wagner, Kathleen L Boyne, Mark J Stevens, Charles E Robertson, Jonathan K Harris, Theresa A Laguna
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0257838 (2021)
RationaleChronic airway infection and inflammation resulting in progressive, obstructive lung disease is the leading cause of morbidity and mortality in cystic fibrosis. Understanding the lower airway microbiota across the ages can provide valuable i
Externí odkaz:
https://doaj.org/article/d0321265d8184464ad546af551bcee45
Publikováno v:
SAGE Open Medical Case Reports, Vol 8 (2020)
Newborn screening for cystic fibrosis is universal across the United States; however, each state chooses the method by which they screen. Illinois employs a two-step process which includes the measurement of the immunoreactive trypsinogen followed by
Externí odkaz:
https://doaj.org/article/a06628ba75f2499581fa9dcae44e726c
Autor:
Alexander L Bisch, Courtney M Wheatley, Sarah E Baker, Elizabeth R Peitzman, Erik H Van Iterson, Theresa A Laguna, Wayne J Morgan, Eric M Snyder
Publikováno v:
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, Vol 13 (2019)
Background: Cystic fibrosis (CF) is a genetic disease affecting multiple organ systems of the body and is characterized by mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR). Previous work has shown that a
Externí odkaz:
https://doaj.org/article/8eef6bf0bf7647a4a12c2b67f9fc2f52
Airway Microbiota in Bronchoalveolar Lavage Fluid from Clinically Well Infants with Cystic Fibrosis.
Autor:
Theresa A Laguna, Brandie D Wagner, Cynthia B Williams, Mark J Stevens, Charles E Robertson, Cole W Welchlin, Catherine E Moen, Edith T Zemanick, Jonathan K Harris
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167649 (2016)
Upper airway cultures guide the identification and treatment of lung pathogens in infants with cystic fibrosis (CF); however, this may not fully reflect the spectrum of bacteria present in the lower airway. Our objectives were to characterize the air
Externí odkaz:
https://doaj.org/article/05fc0bbb261c4b92b33321222f690b3b
Autor:
Nick B Paulson, Adam J Gilbertsen, Joseph J Dalluge, Cole W Welchlin, John Hughes, Wei Han, Timothy S Blackwell, Theresa A Laguna, Bryan J Williams
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111441 (2014)
The arginine decarboxylase pathway, which converts arginine to agmatine, is present in both humans and most bacterial pathogens. In humans agmatine is a neurotransmitter with affinities towards α2-adrenoreceptors, serotonin receptors, and may inhibi
Externí odkaz:
https://doaj.org/article/bc39a391a1704780b513dcbbf2e069db
Autor:
Monica E. Kruk, Subina Mehta, Kevin Murray, LeeAnn Higgins, Katherine Do, James E. Johnson, Reid Wagner, Chris H. Wendt, John B. O’Connor, J. Kirk Harris, Theresa A. Laguna, Pratik D. Jagtap, Timothy J. Griffin
Publikováno v:
mSystems, Vol 9, Iss 7 (2024)
ABSTRACT Airway microbiota are known to contribute to lung diseases, such as cystic fibrosis (CF), but their contributions to pathogenesis are still unclear. To improve our understanding of host-microbe interactions, we have developed an integrated a
Externí odkaz:
https://doaj.org/article/e36a430e5a754b0e804f12b6ccd9536c
Autor:
Edith T Zemanick, J Kirk Harris, Brandie D Wagner, Charles E Robertson, Scott D Sagel, Mark J Stevens, Frank J Accurso, Theresa A Laguna
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62917 (2013)
Pulmonary exacerbations (PEx), frequently associated with airway infection and inflammation, are the leading cause of morbidity in cystic fibrosis (CF). Molecular microbiologic approaches detect complex microbiota from CF airway samples taken during
Externí odkaz:
https://doaj.org/article/104336e4078546e084d8ed636e9ba635
Autor:
Ana Gabriela Soares Silva, Fernanda Dias de Paula, Nelson Rannieri Tirone, Maria Theresa Cerávolo Laguna Abreu
Publikováno v:
Revista Brasileira de Extensão Universitária, Vol 14, Iss 3 (2023)
No Brasil, jovens de 18 anos ao participarem dos tiros de guerra (TG) são convidados a realizarem atividades junto à comunidade, entre elas, a realização da doação de sangue (DS). Esta ação, entretanto, muitas vezes é um ato único na vida d
Externí odkaz:
https://doaj.org/article/53ce96ab9b5d414f85d8235ef99f8c92
Autor:
John B. O’Connor, Brandie D. Wagner, J. Kirk Harris, Daniel N. Frank, Diana E. Clabots, Theresa A. Laguna
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionAirway infection and inflammation lead to the progression of obstructive lung disease in persons with cystic fibrosis (PWCF). However, cystic fibrosis (CF) fungal communities, known drivers of CF pathophysiology, remain poorly understood
Externí odkaz:
https://doaj.org/article/6c4c54828ce34dc581befcf5b9402f63
Autor:
Theresa A. Laguna, Cynthia B. Williams, Myra G. Nunez, Cole Welchlin-Bradford, Catherine E. Moen, Cavan S. Reilly, Chris H. Wendt
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background There are urgent needs for clinically relevant biomarkers to identify children with cystic fibrosis (CF) at risk for more progressive lung disease and to serve as outcome measures for clinical trials. Our objective was to investig
Externí odkaz:
https://doaj.org/article/b32dcc037e1940a5b7902b7b7dba7302