Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Theresa A, Zesiewicz"'
Autor:
Christian Rummey, Theresa A. Zesiewicz, Santiago Perez‐Lloret, Jennifer M. Farmer, Massimo Pandolfo, David R. Lynch
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1708-1712 (2020)
Abstract The modified Friedreich Ataxia Rating Scale (mFARS) is a disease specific, exam‐based neurological rating scale commonly used as a outcome measure in clinical trials. While extensive clinimetric testing indicates it’s validity in measuri
Externí odkaz:
https://doaj.org/article/a0b6ae74147544edba099c849dee977f
Publikováno v:
Neurologic Clinics. 41:21-44
Cerebellar ataxia results from damage to the cerebellum and presents as movement incoordination and variability, gait impairment, and slurred speech. Patients with cerebellar ataxia can also have cognitive and mood changes. Although the identificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a451e913951a33b4c083774777c5a7ad
https://doi.org/10.1016/j.ncl.2022.05.002
https://doi.org/10.1016/j.ncl.2022.05.002
Publikováno v:
Expert Rev Neurother
INTRODUCTION: Spinocerebellar ataxias (SCA) are a group of rare neurodegenerative diseases that dramatically affect the lives of affected individuals and their families. Despite having a clear understanding of SCA’s etiology, there are no current s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8eb87b7c19d3763098cdfeeb8e53c3
https://doi.org/10.1080/14737175.2022.2029703
https://doi.org/10.1080/14737175.2022.2029703
Autor:
Chase Kingsbury, Shaila Ghanekar, Yangxin Huang, Yayi Zhao, Tetsuo Ashizawa, Sheng-Han Kuo, Clifton L. Gooch, Theresa A. Zesiewicz
Publikováno v:
Contemporary Clinical Neuroscience ISBN: 9783031243448
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ecfba616e0a6c92f8172176aa29678b
https://doi.org/10.1007/978-3-031-24345-5_29
https://doi.org/10.1007/978-3-031-24345-5_29
Autor:
Theresa A. Zesiewicz, Nicolas Dohse, Clifton L. Gooch, Yarema B. Bezchlibynk, Shaila Ghanekar
Publikováno v:
Tremors ISBN: 0197529658
Despite millions of people being affected by tremor worldwide, information regarding tremor patients’ ethnicity and racial diversity is limited. We examined diversity and inclusivity in two diseases, essential tremor (ET) and Parkinson disease (PD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61a7d988cdf9d9dfc8f7232579a8118a
https://doi.org/10.1093/med/9780197529652.003.0017
https://doi.org/10.1093/med/9780197529652.003.0017
The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications
Autor:
Louisa P. Selvadurai, Susan L. Perlman, George R. Wilmot, Sub H. Subramony, Christopher M. Gomez, Tetsuo Ashizawa, Henry L. Paulson, Chiadi U. Onyike, Liana S. Rosenthal, Haris I. Sair, Sheng-Han Kuo, Eva-Maria Ratai, Theresa A. Zesiewicz, Khalaf O. Bushara, Gülin Öz, Cameron Dietiker, Michael D. Geschwind, Alexandra B. Nelson, Puneet Opal, Talene A. Yacoubian, Peggy C. Nopoulos, Vikram G. Shakkottai, Karla P. Figueroa, Stefan M. Pulst, Peter E. Morrison, Jeremy D. Schmahmann
Spinocerebellar ataxias (SCAs) are progressive neurodegenerative disorders, but there is no metric that predicts disease severity over time. We hypothesized that by developing a new metric, the Severity Factor (S-Factor) using immutable disease param
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9f84d79ecb1e743ffa267784f9f2c4
https://escholarship.org/uc/item/798300bm
https://escholarship.org/uc/item/798300bm
Autor:
J. Chad Hoyle, S. H. Subramony, John M. Flynn, Theresa A. Zesiewicz, Louise A. Corben, Christian Rummey, Katherine D. Mathews, George Wilmot, Lauren Seeberger, Antoine Duquette, David A. Lynch, Grace Yoon, Khalaf Bushara, Richard Roxburgh, Martin B. Delatycki, Susan Perlman, Christopher M. Gomez
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Vol 8, Iss 6, Pp 1239-1250 (2021)
Annals of Clinical and Translational Neurology, Vol 8, Iss 6, Pp 1239-1250 (2021)
Objective The objective of this study was to characterize the incidence and progression of scoliosis in the natural history of Friedreich’s ataxia (FRDA) and document the factors leading to the requirement for corrective surgery. Methods Data on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3033a09bc54dc45180d9480c5edd3dd6
http://europepmc.org/articles/PMC8164850
http://europepmc.org/articles/PMC8164850
Autor:
Spyros Papapetropoulos, Evan Newbold, Hyder A. Jinnah, Kelly E. Lyons, Margaret Lee, Peter Hedera, Theresa A. Zesiewicz, William G. Ondo, Mark Versavel, Jenna Elder, Rodger J. Elble, Rajesh Pahwa, Stacey Versavel, Adrian Handforth
Publikováno v:
Movement Disorders
Background Available essential tremor (ET) therapies have limitations. Objectives The objective of this study was to evaluate CX-8998, a selective T-type calcium channel modulator, in essential tremor. Methods Patients 18-75 years old with moderate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b71e3622333aa97744e37911ca31b73
http://europepmc.org/articles/PMC8451783
http://europepmc.org/articles/PMC8451783
Autor:
Wassilios G. Meissner, Roberto Eleopra, Taku Hatano, Francisco Grandas, Joseph F. Quinn, Justyna Sarna, Hui Zheng, Osamu Onodera, John T. Slevin, Theresa A. Zesiewicz, Anwar Ahmed, Erika Driver-Dunckley, Tao Xie, Hidek Mochizuki, Deborah A. Hall, John O`Sullivan, Peter A. Ljubenkov, Carlo Colosimo, Tomoko Oeda, Luc Defebvre, Diana R. Kerwin, Hana Florian, Deli Wang, Hoi-Kei Lon, David S. Geldmacher, Nahome Fisseha, Jennifer Hui, Elizabeth Peckham, Noriko Nishikawa, Jean-Christophe Corvol, Günter U. Höglinger, Jared Brosch, Fabienne Ory-Magne, Alberto Albanese, Kumar Budur, Yvette Bordelon, Zbigniew K. Wszolek, Stefano Ruggieri, Akio Kikuchi, James H. Bower, Kelly Bertram, Antonio Daniele, Daryl Wile, Ikuko Aiba, Rajeev Kumar, Lawrence S. Honig, Daniel Claassen, Victor S.C. Fung, Renato P. Munhoz, Beatrice Rendenbach-Mueller, Michael Gold, Ziyi Jin, Albert C. Ludolph, Nuno Mendonca, Ronald B. Postuma, John C. Morgan, Alexandre Eusebio, Aldo Quattrone, Antoine Duquette, Pablo Mir Rivera, Irene Litvan, Thomas E. Kimber, Michele Tagliati, Paola Cudia, Stefan Lorenzl, Takashi Kimura, Zoltan Mari, Hideki Oizumi, Nikolaus R. McFarland, Davis C. Ryman, Lawrence I. Golbe, Paul E Schulz
Publikováno v:
The lancet / Neurology 20(3), 182-192 (2021). doi:10.1016/S1474-4422(20)30489-0
Summary Background Progressive supranuclear palsy is a neurodegenerative disorder associated with tau protein aggregation. Tilavonemab (ABBV-8E12) is a monoclonal antibody that binds to the N-terminus of human tau. We assessed the safety and efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a58b45d2df91f5a39e5802eb0fcc0d
https://doi.org/10.1016/s1474-4422(20)30489-0
https://doi.org/10.1016/s1474-4422(20)30489-0
Autor:
David A. Lynch, Megan O'Grady, Wolfgang Nachbauer, Theresa A. Zesiewicz, Angie Goldsberry, S. H. Subramony, Melanie P. Chin, Colin J. Meyer, Caterina Mariotti, Manuela Corti, J. Chad Hoyle, Martin B. Delatycki, Sylvia Boesch, Susan Perlman, Paola Giunti, Katherine D. Mathews, George Wilmot
Publikováno v:
Annals of Neurology
Objective Friedreich ataxia (FA) is a progressive genetic neurodegenerative disorder with no approved treatment. Omaveloxolone, an Nrf2 activator, improves mitochondrial function, restores redox balance, and reduces inflammation in models of FA. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b4c335d9b32c20ffbf7cba26690a73
http://europepmc.org/articles/PMC7894504
http://europepmc.org/articles/PMC7894504