Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Theresa, Ziemba"'
Autor:
Karen A. Rossi, Ruth R. Wexler, Steven Sheriff, Dawn Sun, Jeffrey M. Bozarth, Jianqing Li, Elizabeth A. Dierks, James R. Corte, Yiming Wu, Donald J. P. Pinto, Silvi A. Chacko, Michael Galella, Joanna J. Zheng, Joseph E. Myers, Dauh-Rurng Wu, Tianan Fang, Joseph M. Luettgen, Pancras C. Wong, Xiaoping Hou, Pabbisetty Kumar Balashanmuga, Daniel Smith, Indawati De Lucca, Huiping Zhang, Wu Yang, Arvind Mathur, Yufeng Wang, Dilger Andrew K, William R. Ewing, Subramaniam Krishnananthan, Yeheng Zhu, Earl J. Crain, Theresa Ziemba
Publikováno v:
Journal of medicinal chemistry. 65(3)
Factor XIa (FXIa) is an enzyme in the coagulation cascade thought to amplify thrombin generation but has a limited role in hemostasis. From preclinical models and human genetics, an inhibitor of FXIa has the potential to be an antithrombotic agent wi
Autor:
Andrew J. Tebben, Wayne Vaccaro, Xiaoxia Yang, Kim W. McIntyre, Steven Sheriff, Nelly Aranibar, Dharmpal S. Dodd, Stacey Skala, Zheng Yang, Dawn K. Stetsko, Patric M Davis, Theresa Ziemba, Suzanne J. Suchard, Dominique Potin, Karishma Patel, Bang-Chi Chen, Joel C. Barrish, Zili Xiao, Albert J. DelMonte, Scott H. Watterson, Murray McKinnon, David R. Tortolani, Praveen Balimane, Pathanjali Kadiyala, Punit Marathe, Huiping Zhang, Michele Launay, Deborah Lee, ChiehYing Y. Chang, T. G. Murali Dhar
Publikováno v:
Journal of Medicinal Chemistry. 53:3814-3830
Leukocyte function-associated antigen-1 (LFA-1), also known as CD11a/CD18 or alpha(L)beta(2), belongs to the beta(2) integrin subfamily and is constitutively expressed on all leukocytes. The major ligands of LFA-1 include three intercellular adhesion
Autor:
Scott H, Watterson, Zili, Xiao, Dharmpal S, Dodd, David R, Tortolani, Wayne, Vaccaro, Dominique, Potin, Michele, Launay, Dawn K, Stetsko, Stacey, Skala, Patric M, Davis, Deborah, Lee, Xiaoxia, Yang, Kim W, McIntyre, Praveen, Balimane, Karishma, Patel, Zheng, Yang, Punit, Marathe, Pathanjali, Kadiyala, Andrew J, Tebben, Steven, Sheriff, Chiehying Y, Chang, Theresa, Ziemba, Huiping, Zhang, Bang-Chi, Chen, Albert J, DelMonte, Nelly, Aranibar, Murray, McKinnon, Joel C, Barrish, Suzanne J, Suchard, T G, Murali Dhar
Publikováno v:
Journal of medicinal chemistry. 53(9)
Leukocyte function-associated antigen-1 (LFA-1), also known as CD11a/CD18 or alpha(L)beta(2), belongs to the beta(2) integrin subfamily and is constitutively expressed on all leukocytes. The major ligands of LFA-1 include three intercellular adhesion