Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Therapy development"'
Autor:
Dennis S. Metselaar, Michaël H. Meel, Joshua R. Goulding, Aimeé du Chatinier, Leyla Rigamonti, Piotr Waranecki, Neal Geisemeyer, Mark C. de Gooijer, Marjolein Breur, Jan Koster, Sophie E.M. Veldhuijzen van Zanten, Marianna Bugiani, Niels E. Franke, Alyssa Reddy, Pieter Wesseling, Gertjan J.L. Kaspers, Esther Hulleman
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101700- (2024)
Summary: Atypical teratoid/rhabdoid tumors (ATRTs) are highly malignant embryonal tumors of the central nervous system with a dismal prognosis. Using a newly developed and validated patient-derived ATRT culture and xenograft model, alongside a panel
Externí odkaz:
https://doaj.org/article/dad8aa161f6e4aad834b1c8a6839ea6b
Autor:
Anneliene Hechtelt Jonker, Daniel O’Connor, Maria Cavaller-Bellaubi, Christine Fetro, Maria Gogou, Peter A. C. ’T Hoen, Martin de Kort, Heather Stone, Nivedita Valentine, Anna Maria Gerdina Pasmooij
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Repurposing is one of the key opportunities to address the unmet rare diseases therapeutic need. Based on cases of drug repurposing in small population conditions, and previous work in drug repurposing, we analyzed the most important lessons learned,
Externí odkaz:
https://doaj.org/article/cc6f95ef5fa542e780aabb40d1b8199f
Autor:
Eugenia Hernandez-Ruiz, Jill Sullivan
Publikováno v:
Voices, Vol 23, Iss 3 (2023)
Music therapy in Mexico has a limited history, with isolated efforts to establish the discipline, lack of university programs, and limited public awareness of the profession. Given the lack of research about music therapy in Mexico, we implemented a
Externí odkaz:
https://doaj.org/article/b6234eee340e4204a6d4ff3c8b8bc459
Akademický článek
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Akademický článek
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Autor:
Dorian M. Cheff, Alysson R. Muotri, Brent R. Stockwell, Edward E. Schmidt, Qitao Ran, Reena V. Kartha, Simon C. Johnson, Plavi Mittal, Elias S. J. Arnér, Kristen M. Wigby, Matthew D. Hall, Sanath Kumar Ramesh
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-15 (2021)
Abstract Background Extremely rare progressive diseases like Sedaghatian-type Spondylometaphyseal Dysplasia (SSMD) can be neonatally lethal and therefore go undiagnosed or are difficult to treat. Recent sequencing efforts have linked this disease to
Externí odkaz:
https://doaj.org/article/b03c183bb33b4ee8b5828e0234f4c132
Akademický článek
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Autor:
Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce Jr., Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction A chemogenomic set of small molecules with annotated activities and implicated roles in Alzheimer's disease (AD) called the AD Informer Set was recently developed and made available to the AD research community: https://treatad.
Externí odkaz:
https://doaj.org/article/b33c64d9d5fa4d89ad4554a76c6b0930
Autor:
Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce, Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction The portfolio of novel targets to treat Alzheimer's disease (AD) has been enriched by the Accelerating Medicines Partnership Program for Alzheimer's Disease (AMP AD) program. Methods Publicly available resources, such as literat
Externí odkaz:
https://doaj.org/article/e2d6a7a95cd548b0ab470f7102528da7
Autor:
Hans‐Olov Adami, Anton Berns, Julio E. Celis, Elisabeth deVries, Alexander Eggermont, Adrian Harris, Harald zur Hausen, Pier Giuseppe Pelicci, Ulrik Ringborg
Publikováno v:
Molecular Oncology, Vol 12, Iss 11, Pp 1829-1837 (2018)
The European Academy of Cancer Sciences (EACS) is an independent advisory body of well‐recognised medical specialists and researchers striving to create a compelling interactive continuum of cancer research, from innovative basic research to implem
Externí odkaz:
https://doaj.org/article/d36ad8c5e4ae4293b29f8af9c192bf40