Zobrazeno 1 - 10
of 7 097
pro vyhledávání: '"Therapeutic strategy"'
Autor:
Zhao Jinyu, Yue Ping, Mi Ningning, Li Matu, Fu Wenkang, Zhang Xianzhuo, Gao Long, Bai Mingzhen, Tian Liang, Jiang Ningzu, Lu Yawen, Ma Haidong, Dong Chunlu, Zhang Yong, Zhang Hengwei, Zhang Jinduo, Ren Yanxian, Suzuki Azumi, Wong Peng F., Tanaka Kiyohito, Rerknimitr Rungsun, Junger Henrik H., Cheung Tan T., Melloul Emmanuel, Demartines Nicolas, Leung Joseph W., Yao Jia, Yuan Jinqiu, Lin Yanyan, Schlitt Hans J., Meng Wenbo
Publikováno v:
Medical Review, Vol 4, Iss 4, Pp 326-365 (2024)
Fibrosis resulting from pathological repair secondary to recurrent or persistent tissue damage often leads to organ failure and mortality. Biliary fibrosis is a crucial but easily neglected pathological feature in hepatobiliary disorders, which may p
Externí odkaz:
https://doaj.org/article/f00ec880e3164f95b5225644f4d94ec7
Autor:
Xiang Yao, Hongyuan Liu, Yuxuan Ma, Minjie Hu, Chong Wang, Han Miao, ShengJie Liu, Jilei Tang
Publikováno v:
Orthopaedic Surgery, Vol 16, Iss 8, Pp 1903-1911 (2024)
Objectives Tibial tubercle is a crucial player in maintaining the structural integrity and functional stability of the knee joint. Currently, there is no standardized protocol for the classification and treatment of tibial tubercle fractures in adult
Externí odkaz:
https://doaj.org/article/a49672bd797146afb63ac87efbb3c05a
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Hepatocellular carcinoma (HCC), an aggressive malignancy with a dismal prognosis, poses a significant public health challenge. Recent research has highlighted the crucial role of lipid metabolism in HCC development, with enhanced lipid synth
Externí odkaz:
https://doaj.org/article/64ea9247b2f2407f92af95d24edf84da
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Recently, research on the human microbiome, especially concerning the bacteria within the digestive system, has substantially advanced. This exploration has unveiled a complex interplay between microbiota and health, particularly in the cont
Externí odkaz:
https://doaj.org/article/9548a515d33140d38daf666561185f1c
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 2, Pp 429-436 (2024)
CircRNAs are a class of single-stranded RNAs characterized by covalently looped structures. Emerging advances have promoted our understanding of circRNA biogenesis, nuclear export, biological functions, and functional mechanisms. Roles of circRNAs in
Externí odkaz:
https://doaj.org/article/666ed27068b04080b1813d0b504b1cb7
Autor:
Li Kaishu, Li Haichao, He Aonan, Zhang Gengqiang, Jin Yuyao, Cai Junbin, Ye Chenle, Qi Ling, Liu Yawei
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1245-1255 (2024)
Glioblastoma (GBM), the most aggressive and fatal brain malignancy, is largely driven by a subset of tumor cells known as cancer stem cells (CSCs). CSCs possess stem cell-like properties, including self-renewal, proliferation, and differentiation, ma
Externí odkaz:
https://doaj.org/article/61ec0d12f48842f9a43e7d7cf50b6f89
Autor:
XIA Dong, YANG Huiling
Publikováno v:
Xin yixue, Vol 55, Iss 5, Pp 373-380 (2024)
Pulmonary fibrosis (PF) is a chronic progressive lung disease that poses a serious health risk. It is mainly characterized by abnormal fibrosis and scarring of lung tissues, resulting in the gradual replacement of alveoli with fibrous tissues a
Externí odkaz:
https://doaj.org/article/64ec80e3fda24d7e9f0f55dcc2c14ea8
Publikováno v:
Xiehe Yixue Zazhi, Vol 15, Iss 3, Pp 479-482 (2024)
The department of critical care medicine has a high prevalence of hospital acquired infections, which are closely associated with prognosis of critically ill patients. With hospital acquired infections as the axis, the treatment of critically ill pat
Externí odkaz:
https://doaj.org/article/d8ae33f471f34be0a01c4fe3d1dfe55a
Autor:
Gholam‐Reza Khosravi, Samaneh Mostafavi, Sanaz Bastan, Narges Ebrahimi, Roya Safari Gharibvand, Nahid Eskandari
Publikováno v:
Cancer Communications, Vol 44, Iss 5, Pp 521-553 (2024)
Abstract Tumors can be classified into distinct immunophenotypes based on the presence and arrangement of cytotoxic immune cells within the tumor microenvironment (TME). Hot tumors, characterized by heightened immune activity and responsiveness to im
Externí odkaz:
https://doaj.org/article/e0f68059fb8f48d7b1206cd6f2c31c3a
Autor:
Thomas Dupas, Amandine Vergnaud, Thomas Pelé, Angélique Blangy-Letheule, Virginie Aillerie, Martin Bouaud, Angélique Erraud, Anaïs Maillard, Dorian Hassoun, Antoine Persello, Jules Lecomte, Matthieu Rivière, Arnaud Tessier, Aurélia A. Leroux, Bertrand Rozec, Manon Denis, Benjamin Lauzier
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Anaesthetics are used daily in human and veterinary medicine as well as in scientific research. Anaesthetics have an impact on cell homeostasis especially through modulation of protein post-translational modifications. O-GlcNAcylation, a ubi
Externí odkaz:
https://doaj.org/article/e452d8210ce14234a433641666b18974