Zobrazeno 1 - 10
of 3 105
pro vyhledávání: '"Therapeutic response"'
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 3, Pp 667-677 (2024)
Lung cancer (LC) is considered to have the highest mortality rate around the world. Because there are no early diagnostic signs or efficient clinical alternatives, distal metastasis and increasing numbers of recurrences are a challenge in the clinica
Externí odkaz:
https://doaj.org/article/b2ce115b1369440c8cb89dc81117a759
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 8, Pp 684-689 (2024)
ObjectiveTo analyze the predictive effect of miRNA-let-7 combined with serum markers on the chemotherapy effect and prognosis of glioma (GBM) patients. MethodsWe collected the data of 25 patients with GBM. Twenty healthy volunteers were included as t
Externí odkaz:
https://doaj.org/article/57929c26c0e7483e87b2b38c5b33de59
Autor:
Sanghoon Lee, Min Sun, Yiheng Hu, Yue Wang, Md N. Islam, David Goerlitz, Peter C. Lucas, Adrian V. Lee, Sandra M. Swain, Gong Tang, Xiao-Song Wang
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Multi-omics sequencing is poised to revolutionize clinical care in the coming decade. However, there is a lack of effective and interpretable genome-wide modeling methods for the rational selection of patients for personalized interventions.
Externí odkaz:
https://doaj.org/article/e9e5092c3b654f949089fcaec042ef9f
Autor:
Zixu Zhang, David Westover, Zhantong Tang, Yue Liu, Jinghan Sun, Yunxi Sun, Runqing Zhang, Xingyue Wang, Shihui Zhou, Nigaerayi Hesilaiti, Qi Xia, Zhenfang Du
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Wnt/β-catenin signaling is a critical pathway that influences development and therapeutic response of non-small cell lung cancer (NSCLC). In recent years, many Wnt regulators, including proteins, miRNAs, lncRNAs, and circRNAs, have been fou
Externí odkaz:
https://doaj.org/article/4ed9d1047bf4444f8b031273f0e24e68
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Autoimmune rheumatic diseases (ARD) present a significant global health challenge characterized by a rising prevalence. These highly heterogeneous diseases involve complex pathophysiological mechanisms, leading to variable treatment efficacies across
Externí odkaz:
https://doaj.org/article/ce8b7201d5954035a472bfcb4e892f84
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionThe significance of ligand-receptor (LR) pair interactions in the progression of acute myeloid leukemia (AML) has been the focus of numerous studies. However, the relationship between LR pairs and the prognosis of AML, as well as their im
Externí odkaz:
https://doaj.org/article/9f16cbd24af2467ea43c1d46e788c1c5
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-18 (2024)
Abstract Background PCD-related long non-coding RNAs (PRLs) are rarely investigated in relation to clear cell renal carcinoma (ccRCC). As part of this study, we evaluated the immunological potential of PRL signatures as a biomarker for ccRCC prognosi
Externí odkaz:
https://doaj.org/article/ee24712a7fb949a5954e06e4597c8fad
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
To investigate the potential clinical value of urinary exosomal (uE) miR-451a as a biomarker for IgAN, urinary exosomes were isolated from 40 patients with IgAN, 30 patients with primary renal diseases without IgA as disease controls (non-IgAN group)
Externí odkaz:
https://doaj.org/article/85ce6f88aef842d0985c994b861121a8
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundOsteosarcoma (OS), a bone tumor with high ability of invasion and metastasis, has seriously affected the health of children and adolescents. Many studies have suggested a connection between OS and the epithelial-mesenchymal transition (EMT)
Externí odkaz:
https://doaj.org/article/941ad6fc797d411eb90ebeb0aea5c2f7
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34784- (2024)
M2 tumor-associated macrophage (M2 TAM), a crucial component of the tumor microenvironment, has a significant impact on tumor invasion and metastasis in the form of angiogenesis for lung adenocarcinoma (LUAD). In this study, both single-cell RNA and
Externí odkaz:
https://doaj.org/article/320e85fd1f9040a0a0b02ef541770ddd