Zobrazeno 1 - 10
of 376
pro vyhledávání: '"Theotokis, P."'
Autor:
Katherine S. Josephs, Eleanor G. Seaby, Philippa May, Pantazis Theotokis, Jing Yu, Avgi Andreou, Hannah Sinclair, Deborah Morris-Rosendahl, Ellen R. A. Thomas, Sarah Ennis, Angharad M. Roberts, James S. Ware
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-22 (2024)
Abstract Background Cardiomyopathies are clinically important conditions, with a strong genetic component. National genomic initiatives such as 100,000 Genome Project (100KGP) provide opportunity to study these rare conditions at scale beyond convent
Externí odkaz:
https://doaj.org/article/b985ecbe203c455f8e325fbb9ff526b4
Autor:
Iasonas Dermitzakis, Despoina Dimitria Kampitsi, Maria Eleni Manthou, Paschalis Evangelidis, Efstratios Vakirlis, Soultana Meditskou, Paschalis Theotokis
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8118-8147 (2024)
Skin stem cells (SCs) play a pivotal role in supporting tissue homeostasis. Several types of SCs are responsible for maintaining and regenerating skin tissue. These include bulge SCs and others residing in the interfollicular epidermis, infundibulum,
Externí odkaz:
https://doaj.org/article/c3b86ab491444696acf8a92c11c87c78
Autor:
Iasonas Dermitzakis, Despoina Chatzi, Stella Aikaterini Kyriakoudi, Nikolaos Evangelidis, Efstratios Vakirlis, Soultana Meditskou, Paschalis Theotokis, Maria Eleni Manthou
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8239-8267 (2024)
Skin, the largest organ in the human body, is a crucial protective barrier that plays essential roles in thermoregulation, sensation, and immune defence. This complex organ undergoes intricate processes of development. Skin development initiates duri
Externí odkaz:
https://doaj.org/article/5055906fec294da682a26921af6958f4
Autor:
Xiaolei Zhang, Pantazis I. Theotokis, Nicholas Li, the SHaRe Investigators, Caroline F. Wright, Kaitlin E. Samocha, Nicola Whiffin, James S. Ware
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background One of the major hurdles in clinical genetics is interpreting the clinical consequences associated with germline missense variants in humans. Recent significant advances have leveraged natural variation observed in large-scale hum
Externí odkaz:
https://doaj.org/article/696f2ae58f374123a9cf5ed1249bfe43
Autor:
Anthi Vasilopoulou, Marina Spaho, Paschalis Theotokis, Alexandra Grekou, Soultana Meditskou, Maria Eleni Manthou
Publikováno v:
Medical Mycology Case Reports, Vol 45, Iss , Pp 100662- (2024)
Disseminated histoplasmosis is the form of a mycosis caused by the fungus Histoplasma capsulatum that mainly occurs in immunosuppressed hosts, usually with non-specific symptoms. In non-endemic areas, where the disease is rarely involved in the diffe
Externí odkaz:
https://doaj.org/article/e1c9aee3cdb24d4cb0476cdb0f50c17c
Autor:
Paschalis Theotokis
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 1754-1756 (2024)
Investigating the subtle molecular mechanisms underlying demyelinating disorders of the central nervous system (CNS) is pivotal in advancing therapeutic strategies and improving patient outcomes [...]
Externí odkaz:
https://doaj.org/article/8a49d969c9b343e5bb11ee2ca1b45d4b
Autor:
Katherine S. Josephs, Angharad M. Roberts, Pantazis Theotokis, Roddy Walsh, Philip J. Ostrowski, Matthew Edwards, Andrew Fleming, Courtney Thaxton, Jason D. Roberts, Melanie Care, Wojciech Zareba, Arnon Adler, Amy C. Sturm, Rafik Tadros, Valeria Novelli, Emma Owens, Lucas Bronicki, Olga Jarinova, Bert Callewaert, Stacey Peters, Tom Lumbers, Elizabeth Jordan, Babken Asatryan, Neesha Krishnan, Ray E. Hershberger, C. Anwar A. Chahal, Andrew P. Landstrom, Cynthia James, Elizabeth M. McNally, Daniel P. Judge, Peter van Tintelen, Arthur Wilde, Michael Gollob, Jodie Ingles, James S. Ware
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background As the availability of genomic testing grows, variant interpretation will increasingly be performed by genomic generalists, rather than domain-specific experts. Demand is rising for laboratories to accurately classify variants in
Externí odkaz:
https://doaj.org/article/b19fec6981b54abc9f8f6edd48178160
Autor:
Yehuda Goldberg, Shir Segal, Liel Hamdi, Hanan Nabat, Nina Fainstein, Efrat Mediouni, Yarden Asis, Paschalis Theotokis, Ilias Salamotas, Nikolaos Grigoriadis, Abram Katz, Tamir Ben-Hur, Ofira Einstein
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The impact of high-intensity interval training (HIIT) on the central nervous system (CNS) in autoimmune neuroinflammation is not known. The aim of this study was to determine the direct effects of HIIT on the CNS and development of experimen
Externí odkaz:
https://doaj.org/article/98ee30eec7ce4b74bfc688116a1718e1
Autor:
Sofia Chatzianagnosti, Iasonas Dermitzakis, Paschalis Theotokis, Eleni Kousta, George Mastorakos, Maria Eleni Manthou
Publikováno v:
Life, Vol 14, Iss 9, p 1161 (2024)
Infertility is a global phenomenon that impacts people of both the male and the female sex; it is related to multiple factors affecting an individual’s overall systemic health. Recently, investigators have been using mesenchymal stem cell (MSC) the
Externí odkaz:
https://doaj.org/article/9a5e41dd19e949078c03cb0a5d7f2762
Autor:
Stella Aikaterini Kyriakoudi, Despoina Chatzi, Iasonas Dermitzakis, Sofia Gargani, Maria Eleni Manthou, Soultana Meditskou, Paschalis Theotokis
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 261 (2024)
The neural crest (NC), also known as the “fourth germ layer”, is an embryonic structure with important contributions to multiple tissue and organ systems. Neural crest cells (NCCs) are subjected to epithelial to mesenchymal transition and migrate
Externí odkaz:
https://doaj.org/article/e723d32d8ac74fbe9445c5183e261acc