Zobrazeno 1 - 10
of 689
pro vyhledávání: '"Theory Article"'
Autor:
Daniel Richard, Terence D. Capellini
Publikováno v:
Aging (Albany NY)
Epigenetic shifts are a hallmark of aging that impact transcriptional networks at regulatory level. These shifts may modify the effects of genetic regulatory variants during aging and contribute to disease pathomechanism. However, these shifts occur
Autor:
John Bickle
Publikováno v:
AIMS Neuroscience
AIMS Neuroscience, Vol 8, Iss 3, Pp 322-339 (2021)
AIMS Neuroscience, Vol 8, Iss 3, Pp 322-339 (2021)
I recount some landmark discoveries that initially confirmed the cyclic AMP response element-binding (CREB) protein-memory consolidation and allocation linkages. This work constitutes one of the successes of the field of Molecular and Cellular Cognit
Autor:
Robert A. Moss
Publikováno v:
AIMS Neuroscience, Vol 7, Iss 3, Pp 194-207 (2020)
AIMS Neuroscience
AIMS Neuroscience
The current paper provides an explanation of neurophysiological pain processing based the Dimensional Systems Model (DSM), a theory of higher cortical functions in which the cortical column is considered the binary digit for all cortical functions. W
Autor:
Larry Vandervert
Publikováno v:
AIMS Neuroscience, Vol 7, Iss 3, Pp 333-343 (2020)
AIMS Neuroscience
AIMS Neuroscience
Based on advances in cerebellum research as to its cognitive, social, and language contributions to working memory, the purpose of this article is to describe new support for the prominent involvement of cerebellar internal models in the adaptive sel
Autor:
Lee D. Hansen, Isabella James, John C. Price, Hsien-Jung L Lin, Ji Sun Park, Richard S. Criddle
Publikováno v:
Aging (Albany NY)
Many amyloid-driven pathologies have both genetic and stochastic components where assessing risk of disease development requires a multifactorial assessment where many of the variables are poorly understood. Risk of transthyretin-mediated amyloidosis
Autor:
Grosse, Laurent, Bulavin, Dmitry V.
Publikováno v:
Aging (Albany NY)
Data obtained from genetically modified mouse models suggest a detrimental role for p16High senescent cells in physiological aging and age-related pathologies. Our recent analysis of aging mice revealed a continuous and noticeable accumulation of liv
Publikováno v:
Bulletin of Chemical Reaction Engineering & Catalysis, Vol 6, Iss 2, Pp 123-128 (2011)
Impeller submergence governs the performance of mixing tanks employed in oxygen transfer operation. Present work experimentally investigates the effect of impeller submergence depths on oxygen transfer and corresponding power consumption. It has been
Externí odkaz:
https://doaj.org/article/269b3798839a4b8d8e967d8876a67059
Autor:
Dennis Mangan
Publikováno v:
Aging (Albany NY)
Iron is an essential element for virtually all living organisms, but its reactivity also makes it potentially harmful. Iron accumulates with aging, and is associated with many age-related diseases; it also shortens the lifespans of several model orga
Publikováno v:
Aging (Albany NY)
Aging is debatably one of the biggest mysteries for humanity, a process consisting of myriads of genetic, molecular, environmental, and stochastic deleterious events, leading to a progressive loss of organism functionality. Aging research currently l
Autor:
Jennifer Howard-Grenville
The Covid-19 pandemic made important societal issues even more pressing and poignant to organizations. I explore how the pandemic surfaced attention to the vulnerability and resilience of organizations and organizing, and reflect on our responsibilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0415a2d1101d4106a63aa04d822142cc