Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Theophile Ohlmann"'
Autor:
Philippe Mangeot, Kristell Lazou, Aurelia Blin, Valerie Gorzelanczyk, Olivier Jeanneton, Chantal Kurfurst, Karl Pays, Bruno Bavouzet, Carine Nizard, Theophile Ohlmann, Anne-Laure Bulteau
Publikováno v:
Cosmetics, Vol 11, Iss 3, p 91 (2024)
Objective: Many severe acute respiratory infections are caused by viral pathogens, and viruses are responsible for a large number of deaths worldwide. Among the most common respiratory viruses are the influenza A virus (IAV) and, more recently, the S
Externí odkaz:
https://doaj.org/article/9a714a33682341a4ac3baf678d5456fc
Autor:
Nannan Wu, Xuan-Nhi Nguyen, Li Wang, Romain Appourchaux, Chengfei Zhang, Baptiste Panthu, Henri Gruffat, Chloé Journo, Sandrine Alais, Juliang Qin, Na Zhang, Kevin Tartour, Frédéric Catez, Renaud Mahieux, Theophile Ohlmann, Mingyao Liu, Bing Du, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011176 (2023)
[This corrects the article DOI: 10.1371/journal.ppat.1008093.].
Externí odkaz:
https://doaj.org/article/eda1ced904054856aebe7c69698f4dc6
Autor:
Nannan Wu, Xuan-Nhi Nguyen, Li Wang, Romain Appourchaux, Chengfei Zhang, Baptiste Panthu, Henri Gruffat, Chloé Journo, Sandrine Alais, Juliang Qin, Na Zhang, Kevin Tartour, Frédéric Catez, Renaud Mahieux, Theophile Ohlmann, Mingyao Liu, Bing Du, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008093 (2019)
ISG20 is a broad spectrum antiviral protein thought to directly degrade viral RNA. However, this mechanism of inhibition remains controversial. Using the Vesicular Stomatitis Virus (VSV) as a model RNA virus, we show here that ISG20 interferes with v
Externí odkaz:
https://doaj.org/article/fd5eb53e1ce84c2d8b20cc67e6f77bbd
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2015, 472 (1), pp.111-119. ⟨10.1042/BJ20150772⟩
Biochemical Journal, 2015, 472 (1), pp.111-119. ⟨10.1042/BJ20150772⟩
Biochemical Journal, Portland Press, 2015, 472 (1), pp.111-119. ⟨10.1042/BJ20150772⟩
Biochemical Journal, 2015, 472 (1), pp.111-119. ⟨10.1042/BJ20150772⟩
mRNA is bound to a complex network of hundreds of RNA-binding proteins (RBPs) which constitute the mature ribonucleoprotein (mRNP). Such a complex particle is initially scaffolded in the nucleus and stays associated throughout mRNA's journey to the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863bbfc15b403f5fc3d1d95c3d30d4ab
https://hal.archives-ouvertes.fr/hal-01871554
https://hal.archives-ouvertes.fr/hal-01871554
Autor:
Gabriel Therizols, Zeina Bash-Imam, Baptiste Panthu, Christelle Machon, Anne Vincent, Julie Ripoll, Sophie Nait-Slimane, Mounira Chalabi-Dchar, Angéline Gaucherot, Maxime Garcia, Florian Laforêts, Virginie Marcel, Jihane Boubaker-Vitre, Marie-Ambre Monet, Céline Bouclier, Christophe Vanbelle, Guillaume Souahlia, Elise Berthel, Marie Alexandra Albaret, Hichem C. Mertani, Michel Prudhomme, Martin Bertrand, Alexandre David, Jean-Christophe Saurin, Philippe Bouvet, Eric Rivals, Théophile Ohlmann, Jérôme Guitton, Nicole Dalla Venezia, Julie Pannequin, Frédéric Catez, Jean-Jacques Diaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Different mechanisms have been reported to explain resistance to chemotherapy in cancer. Here, the authors show that the chemotherapeutic drug 5-fluorouracil alters the function of ribosomes to promote pro-survival gene translation leading to chemoth
Externí odkaz:
https://doaj.org/article/8864c0c71ca844a0835d6a8c1a22dd59
Autor:
Philippe E. Mangeot, Valérie Risson, Floriane Fusil, Aline Marnef, Emilie Laurent, Juliana Blin, Virginie Mournetas, Emmanuelle Massouridès, Thibault J. M. Sohier, Antoine Corbin, Fabien Aubé, Marie Teixeira, Christian Pinset, Laurent Schaeffer, Gaëlle Legube, François-Loïc Cosset, Els Verhoeyen, Théophile Ohlmann, Emiliano P. Ricci
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
A current challenge in genome editing is delivering Cas9 and sgRNA into target cells. Here the authors engineer a delivery system based on murine leukemia virus-like particles loaded with Cas9-sgRNA ribonucleoproteins to induce efficient genome editi
Externí odkaz:
https://doaj.org/article/0bd13889c5db4e0ba26c33892287ae45
Publikováno v:
Viruses, Vol 14, Iss 7, p 1505 (2022)
The SARS-CoV-2 infection generates up to nine different sub-genomic mRNAs (sgRNAs), in addition to the genomic RNA (gRNA). The 5′UTR of each viral mRNA shares the first 75 nucleotides (nt.) at their 5′end, called the leader, but differentiates by
Externí odkaz:
https://doaj.org/article/fee9949b88f34352a44763685e8d9c8c
Autor:
Hélène Duplus-Bottin, Martin Spichty, Gérard Triqueneaux, Christophe Place, Philippe Emmanuel Mangeot, Théophile Ohlmann, Franck Vittoz, Gaël Yvert
Publikováno v:
eLife, Vol 10 (2021)
Optogenetics enables genome manipulations with high spatiotemporal resolution, opening exciting possibilities for fundamental and applied biological research. Here, we report the development of LiCre, a novel light-inducible Cre recombinase. LiCre is
Externí odkaz:
https://doaj.org/article/cbd3da8ae1fc41cdaf82425df6b40433
Publikováno v:
Viruses, Vol 7, Iss 8, Pp 4326-4351 (2015)
Post-transcriptional control in both HIV-1 and HIV-2 is a highly regulated process that commences in the nucleus of the host infected cell and finishes by the expression of viral proteins in the cytoplasm. Expression of the unspliced genomic RNA is p
Externí odkaz:
https://doaj.org/article/40ef3e4daf6341dba458e847e8b779c6
Publikováno v:
Cells, Vol 8, Iss 6, p 574 (2019)
The translation of selenoprotein mRNAs involves a non-canonical ribosomal event in which an in-frame UGA is recoded as a selenocysteine (Sec) codon instead of being read as a stop codon. The recoding machinery is centered around two dedicated RNA com
Externí odkaz:
https://doaj.org/article/b4f223641178404fa72f0ad99576a24b