Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Theodorus H, van der Kwast"'
Autor:
Jethro C. C. Kwong, Jeremy Wu, Shamir Malik, Adree Khondker, Naveen Gupta, Nicole Bodnariuc, Krishnateja Narayana, Mikail Malik, Theodorus H. van der Kwast, Alistair E. W. Johnson, Alexandre R. Zlotta, Girish S. Kulkarni
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Accurate prediction of recurrence and progression in non-muscle invasive bladder cancer (NMIBC) is essential to inform management and eligibility for clinical trials. Despite substantial interest in developing artificial intelligence (AI) ap
Externí odkaz:
https://doaj.org/article/30b7b1ffba8f4f0db8849c53dde71700
Autor:
Jethro C C Kwong, MD, Adree Khondker, BHSc, Eric Meng, BSc, Nicholas Taylor, BSc, Cynthia Kuk, MSc, Nathan Perlis, MD, Girish S Kulkarni, ProfMD, Robert J Hamilton, MD, Neil E Fleshner, ProfMD, Antonio Finelli, ProfMD, Theodorus H van der Kwast, ProfMD, Amna Ali, BSc, Munir Jamal, MD, Frank Papanikolaou, MD, Thomas Short, MD, John R Srigley, ProfMD, Valentin Colinet, MD, Alexandre Peltier, ProfMD, Romain Diamand, MD, Yolene Lefebvre, MD, Qusay Mandoorah, MD, Rafael Sanchez-Salas, MD, Petr Macek, MD, Xavier Cathelineau, ProfMD, Martin Eklund, ProfPhD, Alistair E W Johnson, DPhil, Andrew Feifer, MD, Alexandre R Zlotta, ProfMD
Publikováno v:
The Lancet: Digital Health, Vol 5, Iss 7, Pp e435-e445 (2023)
Summary: Background: Accurate prediction of side-specific extraprostatic extension (ssEPE) is essential for performing nerve-sparing surgery to mitigate treatment-related side-effects such as impotence and incontinence in patients with localised pros
Externí odkaz:
https://doaj.org/article/9e48ab8efa664112a1f3da359fa83dba
Autor:
Kenneth Wenger, Kayvan Tirdad, Alex Dela Cruz, Andrea Mari, Mayada Basheer, Cynthia Kuk, Bas W.G. van Rhijn, Alexandre R. Zlotta, Theodorus H. van der Kwast, Alireza Sadeghian
Publikováno v:
Machine Learning with Applications, Vol 9, Iss , Pp 100347- (2022)
Recent advances in semi-supervised learning algorithms (SSL) have made great strides in reducing the training dependency on labeled datasets and requiring that only a subset of the data be labeled. The presented work explores a class of semi-supervis
Externí odkaz:
https://doaj.org/article/5cc4f0b5b9084cd097e951809ec524a1
Autor:
Khashayar Habibi, Kayvan Tirdad, Alex Dela Cruz, Kenneth Wenger, Andrea Mari, Mayada Basheer, Cynthia Kuk, Bas W.G. van Rhijn, Alexandre R. Zlotta, Theodorus H. van der Kwast, Alireza Sadeghian
Publikováno v:
Machine Learning with Applications, Vol 9, Iss , Pp 100387- (2022)
Bladder cancer tissue grading, which assigns a numerical grade reflecting how aggressive a tumor looks under a microscope, is essential to determine the proper course of treatment, design a therapeutic plan and determine prognosis. The major problem
Externí odkaz:
https://doaj.org/article/612fbab594ae42f0bcf7ae6a866e79c4
Autor:
Joseph Longo, Peter J. Mullen, Rosemary Yu, Jenna E. van Leeuwen, Mehdi Masoomian, Dixon T.S. Woon, Yuzhuo Wang, Eric X. Chen, Robert J. Hamilton, Joan M. Sweet, Theodorus H. van der Kwast, Neil E. Fleshner, Linda Z. Penn
Publikováno v:
Molecular Metabolism, Vol 25, Iss , Pp 119-130 (2019)
Objective: The statin family of cholesterol-lowering drugs has been shown to induce tumor-specific apoptosis by inhibiting the rate-limiting enzyme of the mevalonate (MVA) pathway, HMG-CoA reductase (HMGCR). Accumulating evidence suggests that statin
Externí odkaz:
https://doaj.org/article/f03d8eaff63e4e4990bc23cc62eb3734
Autor:
Esmail M Al-Ezzi, Zachary W Veitch, Samer H Salah, Theodorus H Van der Kwast, Tracy L Stockley, Shamini Selvarajah, Tong Zhang, Srikala S Sridhar, Adrian G Sacher, Nazanin Fallah-Rad, Girish S Kulkarni, Alexandre R Zlotta, Antonio Finelli, Aaron R Hansen
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259272 (2021)
BackgroundNon-schistosomiasis related-squamous cell carcinoma of urinary bladder (NSR-SCCUB) is a rare tumor subtype distinct from urothelial carcinoma (UC). Studies assessing molecular biomarkers in bladder cancer have generally focused on UC, and g
Externí odkaz:
https://doaj.org/article/e3799ed33ecf4271a5cb805e2c0260da
Autor:
Mandeep K. Gill, Tania Christova, Ying Y. Zhang, Alex Gregorieff, Liang Zhang, Masahiro Narimatsu, Siyuan Song, Shawn Xiong, Amber L. Couzens, Jiefei Tong, Jonathan R. Krieger, Michael F. Moran, Alexandre R. Zlotta, Theodorus H. van der Kwast, Anne-Claude Gingras, Frank Sicheri, Jeffrey L. Wrana, Liliana Attisano
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The Hippo pathway is frequently dysregulated in cancer. Here, the authors identify NUAK2 as negative regulator of the Hippo pathway from a siRNA kinome screen and show that NUAK2 promotes YAP/TAZ nuclear localisation while NUAK2 is a transcriptional
Externí odkaz:
https://doaj.org/article/d30df4cc14bf4f8f98f52cdb55527dcc
Autor:
Sangeet Ghai, Nathan Perlis, Chantal Atallah, Sarah Jokhu, Kateri Corr, Katherine Lajkosz, Peter F. Incze, Alexandre R. Zlotta, Umesh Jain, Hannah Fleming, Antonio Finelli, Theodorus H. van der Kwast, Masoom A. Haider
Publikováno v:
Radiology. 305:390-398
Background Multiparametric MRI has led to increased detection of clinically significant prostate cancer (csPCa). Micro-US is being investigated for csPCa detection. Purpose To compare multiparametric MRI and micro-US in detecting csPCa (grade group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514504dbdc11bd05589446229a6c35ea
https://doi.org/10.1148/radiol.212163
https://doi.org/10.1148/radiol.212163
Autor:
Yanhong Yu, Katherine Lajkosz, Antonio Finelli, Neil Fleshner, Theodorus H. van der Kwast, Michelle R. Downes
Publikováno v:
Modern Pathology. 35:1695-1701
Pretreatment classification tools are used in prostate cancer to inform patient management. The effect of cribriform pattern 4 (CC) and intraductal carcinoma (IDC) on such nomograms is still underexplored. We analyzed the Cancer of Prostate Risk Asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35fccf8aef969150f521939e0e3b44f
https://doi.org/10.1038/s41379-022-01111-w
https://doi.org/10.1038/s41379-022-01111-w
Autor:
Hilda A. de Barros, Sebastiaan Remmers, Henk B. Luiting, Geert J.L.H. van Leenders, Monique J. Roobol, Elise M. Bekers, Amer Amin, Anne-Maree Haynes, Warick Delprado, Phillip D. Stricker, Henk G. van der Poel, Theodorus H. van der Kwast, Pim J. van Leeuwen
Publikováno v:
de Barros, H A, Remmers, S, Luiting, H B, van Leenders, G J L H, Roobol, M J, Bekers, E M, Amin, A, Haynes, A-M, Delprado, W, Stricker, P D, van der Poel, H G, van der Kwast, T H & van Leeuwen, P J 2022, ' Predictive Value of Cribriform and Intraductal Carcinoma for the Nomogram-based Selection of Prostate Cancer Patients for Pelvic Lymph Node Dissection ', Urology, vol. 168, pp. 156-164 . https://doi.org/10.1016/j.urology.2022.04.043
Urology, 168, 156-164. Elsevier Inc.
Urology, 168, 156-164. Elsevier Inc.
Objective: To assess the predictive value of biopsy-identified cribriform carcinoma and/or intraductal carcinoma (CR/IDC) within the Briganti and MSKCC nomograms predicting lymph node metastasis (LNM) in patients with primary prostate cancer (PCa). M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad422606645cdffc035464b48025121
http://www.scopus.com/inward/record.url?scp=85135504830&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85135504830&partnerID=8YFLogxK