Zobrazeno 1 - 10
of 653
pro vyhledávání: '"Theodoros K"'
Autor:
Anand Swaminath, Marcin Wierzbicki, Sameer Parpia, Vijayananda Kundapur, Sergio Faria, Naseer Ahmed, Alexis Bujold, Khalid Hirmiz, Timothy Owen, Nelson Leong, Kevin Ramchandar, Edith Filion, Harold Lau, Robert Thompson, Brian Yaremko, Zsolt Gabos, Selma Mehiri, James R. Wright, Theodoros K. Tsakiridis, Kathryn Cline, Timothy J. Whelan
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 37, Iss , Pp 145-152 (2022)
Purpose: To report on the Stereotactic Body Radiation Therapy (SBRT) credentialing experience during the Phase III Ontario Clinical Oncology Group (OCOG) LUSTRE trial for stage I non-small cell lung cancer. Methods: Three credentialing requirements w
Externí odkaz:
https://doaj.org/article/0dfb58d755984234bc52727ca70b9654
Autor:
Bob Schiffrin, Jonathan M. Machin, Theodoros K. Karamanos, Anastasia Zhuravleva, David J. Brockwell, Sheena E. Radford, Antonio N. Calabrese
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Interaction of the outer membrane protein (OMP) chaperone SurA and the OMP folding catalyst BAM results in changes in the conformational ensembles of both species, suggesting a mechanism for delivery of OMPs to BAM in Gram-negative bacteria.
Externí odkaz:
https://doaj.org/article/49dc31e55c1c4e7abc6e6cd217e49c7b
Autor:
Antonio N. Calabrese, Bob Schiffrin, Matthew Watson, Theodoros K. Karamanos, Martin Walko, Julia R. Humes, Jim E. Horne, Paul White, Andrew J. Wilson, Antreas C. Kalli, Roman Tuma, Alison E. Ashcroft, David J. Brockwell, Sheena E. Radford
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The chaperone SurA is involved in outer membrane protein (OMP) biogenesis in Gram-negative bacteria, but its mechanism of action is not fully understood. Combining mass spectrometric, biophysical and computational approaches, the authors here show ho
Externí odkaz:
https://doaj.org/article/2047c9564bc341c98f0fa558c55a100a
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The early stages of protein misfolding and aggregation involve disordered and partially folded protein conformers that contain a high degree of dynamic disorder. These dynamic species may undergo large-scale intra-molecular motions of intrinsically d
Externí odkaz:
https://doaj.org/article/72df3476b89d4aeaab15ffa13b618827
Publikováno v:
Remote Sensing, Vol 14, Iss 23, p 6017 (2022)
Historically, geoscience has been a prominent domain for applications of computer vision and pattern recognition. The numerous challenges associated with geoscience-related imaging data, which include poor imaging quality, noise, missing values, lack
Externí odkaz:
https://doaj.org/article/be03572235b1469c943f4e049ce350cb
Autor:
Matthew G. Iadanza, Robert Silvers, Joshua Boardman, Hugh I. Smith, Theodoros K. Karamanos, Galia T. Debelouchina, Yongchao Su, Robert G. Griffin, Neil A. Ranson, Sheena E. Radford
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Impaired kidney function can lead to an increase of β2-microglobulin (β2m) serum levels, which can cause β2m aggregation and amyloid fibril formation. Here the authors combine cryo-EM and magic angle spinning NMR measurements to determine the stru
Externí odkaz:
https://doaj.org/article/c2131f4762074ff88b7f948f11bb5fd7
Autor:
Theodoros K Karamanos, Matthew P Jackson, Antonio N Calabrese, Sophia C Goodchild, Emma E Cawood, Gary S Thompson, Arnout P Kalverda, Eric W Hewitt, Sheena E Radford
Publikováno v:
eLife, Vol 8 (2019)
Transient oligomers are commonly formed in the early stages of amyloid assembly. Determining the structure(s) of these species and defining their role(s) in assembly is key to devising new routes to control disease. Here, using a combination of chemi
Externí odkaz:
https://doaj.org/article/ae5e6a17dff3440081ba46090b9199cc
Autor:
Georgia-Eirini Deligiannidou, Vasiliki Gougoula, Eugenia Bezirtzoglou, Christos Kontogiorgis, Theodoros K. Constantinides
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 599 (2021)
Rheumatoid arthritis (RA) is an autoimmune disorder affecting a vast variety of the population. The onset of RA as well as the development of systematic immunization is affected by both genetic and environmental risk factors. This review aims to poin
Externí odkaz:
https://doaj.org/article/0aab390f25b245beb0e61ba084abb3fb
Autor:
Lane, Benjamin J., Ma, Yue, Yan, Nana, Wang, Bolin, Ackermann, Katrin, Karamanos, Theodoros K., Bode, Bela E., Pliotas, Christos
Publikováno v:
In Structure 6 June 2024 32(6):739-750
Publikováno v:
In BBA - Proteins and Proteomics 1 February 2024 1872(2)