Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Theodore S, Kapellos"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/5558324eba744ee2b2bbbd4b6d8e6a87
Autor:
Theodore S. Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C. Schaar, Lorenzo Bonaguro, Tal Pecht, Izabela Galvao, Shobhit Agrawal, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena de Domenico, Arik Horne, Chantal Donovan, Richard Y. Kim, David Gallego-Ortega, Tessa E. Gillett, Meshal Ansari, Jonas Schulte-Schrepping, Nina Offermann, Ignazio Antignano, Burcu Sivri, Wenying Lu, Mathew S. Eapen, Martina van Uelft, Collins Osei-Sarpong, Maarten van den Berge, Hylke C. Donker, Harry J.M. Groen, Sukhwinder S. Sohal, Johanna Klein, Tina Schreiber, Andreas Feißt, Ali Önder Yildirim, Herbert B. Schiller, Martijn C. Nawijn, Matthias Becker, Kristian Händler, Marc Beyer, Melania Capasso, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Fabian J. Theis, Philip M. Hansbro, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112525- (2023)
Summary: Systemic inflammation is established as part of late-stage severe lung disease, but molecular, functional, and phenotypic changes in peripheral immune cells in early disease stages remain ill defined. Chronic obstructive pulmonary disease (C
Externí odkaz:
https://doaj.org/article/de07677bc6c241f3a6d5cd66f2c12fd0
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3d0b395303914b17aeba320ad80606e8
Autor:
Helen G. Hanstock, Theodore S. Kapellos, Holly R. Keir, P. Padmini S.J. Khedoe, Merete B. Long, Elza Evren, Niki D. Ubags, Joana Cruz
Publikováno v:
Breathe, Vol 18, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/b34da1e18b7a4fc5b8ea04f35f8f4ab1
Autor:
Kevin Baßler, Wataru Fujii, Theodore S. Kapellos, Erika Dudkin, Nico Reusch, Ari Horne, Benedikt Reiz, Malte D. Luecken, Collins Osei-Sarpong, Stefanie Warnat-Herresthal, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Allon Wagner, Patrick Günther, Carmen Pizarro, Tina Schreiber, Rainer Knoll, Lisa Holsten, Charlotte Kröger, Elena De Domenico, Matthias Becker, Kristian Händler, Christian T. Wohnhaas, Florian Baumgartner, Meike Köhler, Heidi Theis, Michael Kraut, Marc H. Wadsworth, Travis K. Hughes, Humberto J. Ferreira, Emily Hinkley, Ines H. Kaltheuner, Matthias Geyer, Christoph Thiele, Alex K. Shalek, Andreas Feißt, Daniel Thomas, Henning Dickten, Marc Beyer, Patrick Baum, Nir Yosef, Anna C. Aschenbrenner, Thomas Ulas, Jan Hasenauer, Fabian J. Theis, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite its high prevalence, the cellular and molecular mechanisms of chronic obstructive pulmonary disease (COPD) are far from being understood. Here, we determine disease-related changes in cellular and molecular compositions within the alveolar sp
Externí odkaz:
https://doaj.org/article/e0f1f3d9372546f1a11d2fa5f19b33eb
Autor:
Anna C. Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S. Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D. Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N. Ahmad Aziz, Peter Pickkers, Frank L. van de Veerdonk, Mihai G. Netea, Joachim L. Schultze, Matthijs Kox, Monique M. B. Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J. Giamarellos-Bourboulis, Thomas Ulas, German COVID-19 Omics Initiative (DeCOI)
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-25 (2021)
Abstract Background The SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic, mild respiratory tract infection, to severe cases with acute respiratory d
Externí odkaz:
https://doaj.org/article/00693afe88234ab7b97afcce182c0fb0
Autor:
Wataru Fujii, Theodore S. Kapellos, Kevin Baßler, Kristian Händler, Lisa Holsten, Rainer Knoll, Stefanie Warnat-Herresthal, Marie Oestreich, Emily R. Hinkley, Jan Hasenauer, Carmen Pizarro, Christoph Thiele, Anna C. Aschenbrenner, Thomas Ulas, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Background Immune cells play a major role in the pathogenesis of COPD. Changes in the distribution and cellular functions of major immune cells, such as alveolar macrophages (AMs) and neutrophils are well known; however, their transcriptional reprogr
Externí odkaz:
https://doaj.org/article/ba9c72944c8e44c0884c83b5d5ae110e
Autor:
Sander Tuit, Camilla Salvagno, Theodore S. Kapellos, Cheei-Sing Hau, Lea Seep, Marie Oestreich, Kathrin Klee, Karin E. de Visser, Thomas Ulas, Joachim L. Schultze
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1221-1235.e5 (2019)
Summary: Tumor-associated macrophages (TAMs) are frequently the most abundant immune cells in cancers and are associated with poor survival. Here, we generated TAM molecular signatures from K14cre;Cdh1flox/flox;Trp53flox/flox (KEP) and MMTV-NeuT (Neu
Externí odkaz:
https://doaj.org/article/70ff9767f3654f8da4eabe5c7e22e699
Autor:
Theodore S. Kapellos, Lorenzo Bonaguro, Ioanna Gemünd, Nico Reusch, Adem Saglam, Emily R. Hinkley, Joachim L. Schultze
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Human monocytes are divided in three major populations; classical (CD14+CD16−), non-classical (CD14dimCD16+), and intermediate (CD14+CD16+). Each of these subsets is distinguished from each other by the expression of distinct surface markers and by
Externí odkaz:
https://doaj.org/article/8a1794b9fa2641bfb7ffaeb1a32c65bc
Autor:
Theodore S. Kapellos, Kevin Bassler, Anna C. Aschenbrenner, Wataru Fujii, Joachim L. Schultze
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Chronic obstructive pulmonary disease (COPD) is a diverse respiratory disease characterised by bronchiolitis, small airway obstruction, and emphysema. Innate immune cells play a pivotal role in the disease’s progression, and in particular, lung mac
Externí odkaz:
https://doaj.org/article/6d497e605f5147ef8ccc44c60f07be38