Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Theodore Roth"'
Publikováno v:
The Journal of Immunology. 202:124.9-124.9
Activation of naïve CD4+ T cells by T cell receptor (TCR) stimulation and cytokine cues lead to differentiation into effector T cell populations with distinct pro-inflammatory or regulatory functions. Unlike adult naïve T cells, human fetal naïve
Dissecting the genetic networks that control regulatory T cell stability using pooled CRISPR screens
Autor:
Jessica T. Cortez, Eric Shifrut, Youjin Lee, Maxwell R. Mumbach, Ansuman T. Satpathy, Jeffrey Granja, Meena Subramaniam, Theodore Roth, Dimitre Simeonov, Chun J. Ye, Howard Y. Chang, Frederic Van Gool, Alexander Marson
Publikováno v:
The Journal of Immunology. 200:101.5-101.5
Regulatory T cells (Tregs) are a specialized subset of CD4+ T cells that suppress inflammation to maintain homeostasis and prevent autoimmunity. Treg development and function depend on expression of the master transcription factor Foxp3. While Tregs
Autor:
Linda Thuy Vo, David H. Nguyen, Theodore Roth, Alexander Marson, George Q. Daley, Jeffrey A. Bluestone
Publikováno v:
The Journal of Immunology. 200:103.12-103.12
Immunotherapy has rapidly emerged as a promising treatment for many different types of cancer. Ongoing clinical trials continue to validate the efficacy of T cell-based cancer immunotherapy, such as chimeric antigen receptor (CAR) T cells, as a valid
Autor:
R. Theodore Roth
Publikováno v:
Armed Forces & Society. 18:383-405
The combined pressures of reduced East-West tensions and large budget deficits in the United States have led to the enactment of reduced defense budgets. Future reductions in spending could be 25 percent less in real terms from FY 1990 levels. These
Publikováno v:
The Journal of Immunology. 188:169.7-169.7
Viral infections of brain usually trigger inflammatory responses that give rise to a wide range of pathological outcomes. To gain novel insights into how the brain responds to a virus as it establishes persistence, we utilized genomic and two-photon