Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Theodore R. F. Wright"'
Autor:
Dean G. Stathakis, Theodore R. F. Wright, Sujatha Krishnakumar, Denise Burton, Janis M. O'Donnell, Wilson McIvor
Publikováno v:
Genetics. 153:361-382
We report the genetic, phenotypic, and biochemical analyses of Catecholamines up (Catsup), a gene that encodes a negative regulator of tyrosine hydroxylase (TH) activity. Mutations within this locus are semidominant lethals of variable penetrance tha
Autor:
Theodore R. F. Wright, Dean G. Stathakis, M. E. Freeman, J. Kullman, G. R. Hankins, N. J. Pearlson, Ellen S. Pentz
Publikováno v:
Genetics. 141:629-655
We report the complete molecular organization of the Dopa decarboxylase gene cluster. Mutagenesis screens recovered 77 new Df(2L)TW130 recessive lethal mutations. These new alleles combined with 263 previously isolated mutations in the cluster to def
Publikováno v:
Biochemical Genetics. 28:151-171
The complex enzyme phenol oxidase plays a major role in sclerotization and melanization of cuticle in insects. Production of active enzyme from the inactive proenzyme involves at least six protein components in Drosophila. We examine here the biochem
Autor:
Harald Biessmann, Anne-Yvonne Kermabon, Marika F. Walter, Golnar Afshar, Theodore R. F. Wright, Bruce C. Black
Publikováno v:
Developmental biology. 147(1)
The yellow (y) gene of Drosophila is required for the formation of black melanin and its deposition in the cuticle. We have studied by immunohistochemical methods the temporal and spatial distribution of the protein product of the y gene during embry
Autor:
Ellen S. Pentz, Theodore R. F. Wright
Publikováno v:
Gene. 103(2)
The Drosophila melanogaster diphenol oxidase (DOX) A2-encoding gene ( Dox-A2 ) is involved in catecholamine metabolism, melanin formation and sclerotization of the cuticle. Insect phenol oxidases (POX) are well studied biochemically, but not genetica
Autor:
Ernest V. Falke, Theodore R. F. Wright
Publikováno v:
Genetics. 81:655-682
Thirteen X-linked, cold-sensitive lethal, female-sterile mutants of Drosophila melanogaster located at eight separate loci were screened for their ability to assemble ribosomes at the restrictive temperature of 17°. Females were labelled with 3H-uri
Autor:
Tomsett Ad, Bruce C. Black, Clifton P. Bishop, Wright Ey, Wolfgang Beermann, Theodore R. F. Wright, Ruth Steward, Marsh Jl
Publikováno v:
Chromosoma. 83:45-58
Of 204 mutations located in the 8-12 band Df(2L)130 region, 37B9-C1,2;37D1-2, 199 have been assigned to twelve lethal genes and one visible gene (hook). The 13 genes are not evenly distributed. Twelve, (possibly all thirteen) are in the seven band re
Publikováno v:
Genetics. 76:487-510
A temperature-sensitive lethal allele of suppressor of forked, l(1)su(f)(ts67g) (ts67), has been discovered and characterized as follows: Flies which are hemizygous for ts67 live at 18 degrees and 25 degrees but die at 30 degrees primarily as larvae.
Autor:
Theodore R. F. Wright
Publikováno v:
American Zoologist. 17:707-721
Dopa decarboxylase (DDC) in the Diptera is an enzyme involved in sclerotinization of the cuticle in the epidermis and the production of neurogenic amines in the central nervous system. Its appearance in the epidermis at pupariation is induced by the
Publikováno v:
Molecular and General Genetics MGG. 209:306-312
The dopa decarboxylase gene (Ddc) is located in a very dense cluster of genes many of whose functions appear to be related to the physiological role of dopa decarboxylase (DDC) in catecholamine metabolism. In Drosophila melanogaster catecholamine met