Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Theodore P Trouard"'
Autor:
Yuan Shang, Aarti Mishra, Tian Wang, Yiwei Wang, Maunil Desai, Shuhua Chen, Zisu Mao, Loi Do, Adam S Bernstein, Theodore P Trouard, Roberta D Brinton
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0225392 (2020)
Late onset Alzheimer's disease (LOAD) is a progressive neurodegenerative disease with four well-established risk factors: age, APOE4 genotype, female chromosomal sex, and maternal history of AD. Each risk factor impacts multiple systems, making LOAD
Externí odkaz:
https://doaj.org/article/3bb9947644814241b4b42174b05723b1
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195952 (2018)
Over the past several years, significant efforts have been made to improve the spatial resolution of diffusion-weighted imaging (DWI), aiming at better detecting subtle lesions and more reliably resolving white-matter fiber tracts. A major concern wi
Externí odkaz:
https://doaj.org/article/eeacf5d8d065487ca299f9eccd9e6844
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178179 (2017)
In vivo magnetic resonance imaging (MRI) was used to investigate regional and global brain atrophy in the neurodegenerative Niemann Pick Type C1 (NPC1) disease mouse model. Imaging experiments were conducted with the most commonly studied mouse model
Externí odkaz:
https://doaj.org/article/9fd79dd5c39448eb8f7a7f3b91068f46
Autor:
David A Raichlen, Pradyumna K Bharadwaj, Megan C Fitzhugh, Kari A Haws, Gabrielle-Ann Torre, Theodore P Trouard, Gene E Alexander
Publikováno v:
Frontiers in Human Neuroscience, Vol 10 (2016)
Expertise and training in fine motor skills has been associated with changes in brain structure, function, and connectivity. Fewer studies have explored the neural effects of athletic activities that do not seem to rely on precise fine motor control
Externí odkaz:
https://doaj.org/article/fd61048d0051470c89e0cf975dc10530
Autor:
Hyun Song, Pradyumna K. Bharadwaj, David A. Raichlen, Christian G. Habeck, Matthew D. Grilli, Matthew J. Huentelman, Georg A. Hishaw, Theodore P. Trouard, Gene E. Alexander
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Homocysteine (Hcy) is a cardiovascular risk factor implicated in cognitive impairment and cerebrovascular disease but has also been associated with Alzheimer’s disease. In 160 healthy older adults (mean age = 69.66 ± 9.95 years), we sought to inve
Externí odkaz:
https://doaj.org/article/f5320eed5a0245309c690ea3f60b1ff3
Autor:
Devin P. Murphy, Denali C. Dickson, Arisha N. Fatema, Nolan G. Carrasco, Kristian P. Doyle, Theodore P. Trouard, Helena W. Morrison
Publikováno v:
Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)
Abstract Stroke is a pervasive and debilitating global health concern, necessitating innovative therapeutic strategies, especially during recovery. While existing literature often focuses on acute interventions, our study addresses the uniqueness of
Externí odkaz:
https://doaj.org/article/15e958aeb89b45fda524aa2e38ae0afb
Autor:
Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied. In a coho
Externí odkaz:
https://doaj.org/article/61d96f3f69ff49b89b51d46b436b5c3d
Autor:
Hyun Song, Pradyumna K. Bharadwaj, David A. Raichlen, Christian G. Habeck, Matthew J. Huentelman, Georg A. Hishaw, Theodore P. Trouard, Gene E. Alexander
Publikováno v:
Neurobiology of Aging. 121:129-138
Homocysteine (Hcy) is a vascular risk factor associated with cognitive impairment and cerebrovascular disease but has also been implicated in Alzheimer's disease (AD). Using multivariate Scaled Subprofile Model (SSM) analysis, we sought to identify a
Autor:
Li Chen, Manabu Shirakawa, Wenjin Liu, Jinmei Chen, Niranjan Balu, Dakota Ortega, Wei Zhou, Chun Yuan, Thomas S. Hatsukami, Theodore P. Trouard, Zhensen Chen
Publikováno v:
Magnetic Resonance Imaging. 95:121-124
Autor:
Sara A. Nolin, Hannah Cowart, Stacy Merritt, Katalina McInerney, P. K. Bharadwaj, Mary Kate Franchetti, David A. Raichlen, Cortney J. Jessup, G. Alex Hishaw, Emily J. Van Etten, Theodore P. Trouard, David S. Geldmacher, Virginia G. Wadley, Eric S. Porges, Adam J. Woods, Ron A. Cohen, Bonnie E. Levin, Tatjana Rundek, Gene E. Alexander, Kristina M. Visscher
Publikováno v:
Journal of the International Neuropsychological Society. :1-10
Objective: To evaluate the construct validity of the NIH Toolbox Cognitive Battery (NIH TB-CB) in the healthy oldest-old (85+ years old). Method: Our sample from the McKnight Brain Aging Registry consists of 179 individuals, 85 to 99 years of age, sc