Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Theodore P Ciaraldi"'
Autor:
Sagarika Chakrabarty, Quyen Bui, Leylla Badeanlou, Kelly Hester, Jerold Chun, Wolfram Ruf, Theodore P Ciaraldi, Fahumiya Samad
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 69-83 (2022)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that interacts via 5 G-protein coupled receptors, S1PR1-5, to regulate signalling pathways critical to biological processes including cell growth, immune cell trafficking, and inflammation.We
Externí odkaz:
https://doaj.org/article/b5842b2215f440ccb953cfdf3e9745aa
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 276-286 (2022)
Type 2 Diabetes (T2D) is associated with impaired vascularization of adipose tissue (AT) . IL8, GROα and IL15 are pro-angiogenic myokines, secreted at elevated levels by T2D myotubes. We explored the direct impact of these myokines on AT vasculariza
Externí odkaz:
https://doaj.org/article/c8935d83e3de4315991001497bc40717
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158209 (2016)
Skeletal muscle secretes factors, termed myokines. We employed differentiated human skeletal muscle cells (hSMC) cultured from Type 2 diabetic (T2D) and non-diabetic (ND) subjects to investigate the impact of T2D on myokine secretion. Following 24 ho
Externí odkaz:
https://doaj.org/article/cb31bcbf97c34a2392da4f33905fb5ea
Autor:
Esther Llagostera, Daniele Catalucci, Luc Marti, Marc Liesa, Marta Camps, Theodore P Ciaraldi, Richard Kondo, Sita Reddy, Wolfgang H Dillmann, Manuel Palacin, Antonio Zorzano, Pilar Ruiz-Lozano, Ramon Gomis, Perla Kaliman
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1134 (2007)
Myotonic dystrophy 1 (DM1) is caused by a CTG expansion in the 3'-unstranslated region of the DMPK gene, which encodes a serine/threonine protein kinase. One of the common clinical features of DM1 patients is insulin resistance, which has been associ
Externí odkaz:
https://doaj.org/article/6c86d37245114e479f7100b656b5b6aa
Autor:
Theodore P. Ciaraldi, Schafer C. Boeder, Sunder R. Mudaliar, Erin R. Giovannetti, Robert R. Henry, Jeremy H. Pettus
Publikováno v:
Diabetes, Obesity and Metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404dba9404fdbb172627f9fcc7bd7cb2
https://doi.org/10.1111/dom.15070
https://doi.org/10.1111/dom.15070
Autor:
null Theodore P. Ciaraldi, null Schafer C. Boeder, null Sunder R. Mudaliar, null Erin R. Giovannetti, null Robert R. Henry, null Jeremy H. Pettus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a254d33c97b769c6865260090bf90bed
https://doi.org/10.1111/dom.15070/v2/response1
https://doi.org/10.1111/dom.15070/v2/response1
Publikováno v:
Molecular Biology Reports. 48:601-610
Angiogenesis is a multistep process requiring endothelial cell activation, migration, proliferation and tube formation. We recently reported that elevated secretion of interlukin 8 (IL8) by myotubes (MT) from subjects with Type-2 Diabetes (T2D) reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c976cde83125db71e8d64700a8d28ae
https://doi.org/10.1007/s11033-020-06104-z
https://doi.org/10.1007/s11033-020-06104-z
Autor:
Theodore P. Ciaraldi, Inês S. Lima, Yossi Dagon, Ji A Seo, Achana Vijyakumar, Jee In Heo, Vanita R. Aroda, Robert R. Henry, Hu Huang, Min-Cheol Kang, Won Mo Yang, Kyong Soo Park, Aykut Göktürk Üner, Soo Hong, Won Min Hwang, Sang Soo Kim, Leandro Pereira de Moura, Min Seon Kim, Thomas E. Willnow, Seung-Hwan Lee, Young-Bum Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Crosstalk between liver and skeletal muscle is vital for glucose homeostasis. Hepatokines, liver-derived proteins that play an important role in regulating muscle metabolism, are important to this communication. Here we identify apolipoprotein J (Apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e0dee6dfe3e624b9e0e94556e9b785
http://link.springer.com/article/10.1038/s41467-020-15963-w
http://link.springer.com/article/10.1038/s41467-020-15963-w
Autor:
Byron Hetrick, Alexandra Stanley, Vitor F. Martins, Carrie E. McCurdy, Theodore P. Ciaraldi, Ji E. Park, Samuel LaBarge, Christina Ha, Larry L. David, Andrew Philp, Robert R. Henry, Gretchen A. Meyer, Dion Banoian, Omer Keinan, Joseph E. Aslan, Simon Schenk, Chao-Wei Hung, Kristoffer Svensson, Alan R. Saltiel
Publikováno v:
JCI Insight
JCI insight, vol 7, iss 1
JCI insight, vol 7, iss 1
While current thinking posits that insulin signaling to glucose transporter 4 (GLUT4) exocytic translocation and glucose uptake in skeletal muscle and adipocytes is controlled by phosphorylation-based signaling, many proteins in this pathway are acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b62d5a4416c35d5a5ea314957c13f9
https://doi.org/10.1172/jci.insight.141344
https://doi.org/10.1172/jci.insight.141344
Autor:
Kenneth Cusi, Sue Sha, Diana Barb, Nishanth E. Sunny, David Polidori, Jeremy Pettus, Robert R. Henry, Srilaxmi Kalavalapalli, Sunder Mudaliar, Fernando Bril, Theodore P. Ciaraldi, Kristin Farrell, Atalanta Ghosh
Publikováno v:
Diabetes, Obesity and Metabolism. 21:812-821
AIM To evaluate the impact of the sodium glucose co-transporter 2 inhibitor canagliflozin on intrahepatic triglyceride (IHTG) accumulation and its relationship to changes in body weight and glucose metabolism. MATERIALS AND METHODS In this double-bli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a6a26184433e02862e305d8a4c07a9
https://doi.org/10.1111/dom.13584
https://doi.org/10.1111/dom.13584