Výsledky vyhledávání - "Theodore Lampidis"

Glucose and mannose analogs inhibit KSHV replication by blocking N-glycosylation and inducing the unfolded protein response

Autor: Mariana Schlesinger, Christian McDonald, Anuj Ahuja, Carolina Alejandra Alvarez Canete, Zelmira Nuñez del Prado, Julian Naipauer, Theodore Lampidis, Enrique A. Mesri

Publikováno v: Journal of medical virologyREFERENCES. 95(1)

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent for Kaposi's sarcoma (KS), an HIV/AIDS-associated malignancy. Effective treatments against KS remain to be developed. The sugar analog 2-deoxy- d-glucose (2-DG) is an anticancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c42777ac85dc3401484526013ae2e4
https://pubmed.ncbi.nlm.nih.gov/36380418

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Abstract 1252: Glucose and Mannose sugar analogs negatively affect KSHV replication by inhibiting N-Glycosylation and inducing the Unfolded Protein Response

Autor: Christian McDonald, Marianna Schlesinger, Anuj Ahuja, Carolina Alvarez, Zelmira Nunez, Julian Naipauer, Enrique Mesri, Theodore Lampidis

Publikováno v: Journal of Biological Chemistry. 299:103079

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::436de9a12a402c59e435b7be83b0f145
https://doi.org/10.1016/j.jbc.2023.103079

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Procollagen alpha 1 type 1: a potential aide in histopathological grading of glioma

Autor: Niramol, Savaraj, Chunjing, Wu, Howard, Landy, Medhi, Wangpaijit, Yingjie, Wei, M Tien, Kuo, Carlos, Robles, A J, Furst, Theodore, Lampidis, Lynn, Feun

Publikováno v: Cancer investigation. 23(7)

Collagen type I production has been shown to play a role in malignant transformation. We examined procollagen type I expression in brain tumors and with histopathological grading. Expression levels of procollagen alpha 1 type 1 were determined in 5 g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e05d2a1a00aff360522795a6da8df5a
https://pubmed.ncbi.nlm.nih.gov/16305983

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Abstract 4642: Combined glycolytic inhibition and anti-vascular treatment in retinoblastoma: Novel strategy for tumor control avoids chemotherapy

Autor: Steve Houston, Timothy G. Murray, Christina L. Decatur, Theodore Lampidis, Yolanda Piña

Publikováno v: Cancer Research. 72:4642-4642

Purpose: The purpose of this study was to evaluate the combination treatment of glycolytic inhibitors and anti-angiogenic agents on tumor burden and hypoxia in advanced retinoblastoma using the LHbetaTag murine transgenic retinoblastoma model. Method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4334b07a6fc590071446f40f4b723b93
https://doi.org/10.1158/1538-7445.am2012-4642

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Abstract 2359: Using the glycolytic inhibitor 2-fluorodeoxy-D-glucose, a novel glycolytic inhibitor approach to target the chemoresistant, hypoxic cell population in advanced LHBETATAG retinal tumors

Autor: Timothy G. Murray, Christina L. Decatur, Theodore Lampidis, Yolanda Piña, Samuel K. Houston, Nikesh Shah

Publikováno v: Cancer Research. 72:2359-2359

Purpose: The aim of the current study is to assess the impact of 2-fluorodeoxy-D-glucose on tumor burden and hypoxia in the LHBETATAG retinal tumors. Methods: The study protocol was approved by the University of Miami Institutional Animal Care and Us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::149afe902c8b27a9df01d9a365154dbf
https://doi.org/10.1158/1538-7445.am2012-2359

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