Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Theodore L. Drell"'
Autor:
Corinna Weidt, Bernd Niggemann, Benjamin Kasenda, Theodore Drell, Kurt Zanker, Thomas Dittmar, Theodore L. Drell, Kurt S. Zanker
Publikováno v:
Current Stem Cell Research & Therapy. 2:89-103
Migration is an innate and fundamental cellular function that enables hematopoietic stem cells (HSCs) and endothelial progenitors (EPCs) to leave the bone marrow, relocate to distant tissue, and to return to the bone marrow. An increasing number of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7866b60eaeef9183bbd74bdb1c833915
https://doi.org/10.2174/157488807779317008
https://doi.org/10.2174/157488807779317008
Autor:
Kerstin Lang, Bernd Niggemann, Theodore L. Drell, Frank Entschladen, Kai Masur, Daniel Palm, Kurt S. Zaenker
Publikováno v:
International Journal of Cancer. 118:2744-2749
The development of metastases is a decisive step in the course of a cancer disease. The detection of metastases in cancer patients is correlated with a poor prognosis, and over 90% of all deaths from cancer are not due to the primary tumor, which oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35d4e1a4a7e8a3b1e2a79dc6d2ee00e
https://doi.org/10.1002/ijc.21723
https://doi.org/10.1002/ijc.21723
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 1:69-80
A leading cause of death, cancer remains the bane of modern society and one of the most challenging research fields. Cancer is initially a localized disease that can be often treated well at a very early stage. However the vast majority of cancer dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03490a7cdb68b2614fb9a6da338948e
https://doi.org/10.2174/157489206775246511
https://doi.org/10.2174/157489206775246511
Autor:
Daniel Palm, Frank Entschladen, Philipp Bastian, Kerstin Lang, Kurt S. Zaenker, Bernd Niggemann, Theodore L. Drell, Kai Masur
Publikováno v:
Experimental Cell Research. 307:418-426
The autonomous migration of specialized cells is an essential characteristic in both physiological and pathological functions in the adult human organism. Leukocytes, fibroblasts, and stem cells, but also tumor cells, are thus the subject of intense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5305477f67715b78cd930dc513febbd
https://doi.org/10.1016/j.yexcr.2005.03.029
https://doi.org/10.1016/j.yexcr.2005.03.029
Publikováno v:
Current Pharmaceutical Design. 11:403-411
The migration of tumor cells is a prerequisite for tumor cell invasion and metastasis development, which accounts for over 90% of cancer mortality. Therefore a major focus of current tumor biological research is the study of those factors that regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a1b75d4459472ec1ab887abf71e6b6
https://doi.org/10.2174/1381612053382197
https://doi.org/10.2174/1381612053382197
Autor:
Theodore L. Drell, Frank Entschladen, Philipp Bastian, Daniel Palm, Stefanie Potthoff, Kerstin Lang, Kurt S. Zänker
Publikováno v:
Signal Transduction. 5:9-18
Migration is an essential function of cells; it is involved in reproduction and embryogenesis, as well as in the cellular, immunological defense of an organism against pathogens. On the pathological site, migration of tumor cells represents a pernici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6061acbcaf281c799218e0e2155bbd44
https://doi.org/10.1002/sita.200400036
https://doi.org/10.1002/sita.200400036
Autor:
Bernd Niggemann, Theodore L. Drell, Kurt S. Zaenker, Kerstin Lang, Frank Entschladen, Corinna Weidt, Jan Joseph
Publikováno v:
Experimental Cell Research. 298:178-187
Although great strides have recently been made in elucidating the factors initiating tumor cell migration and the relevant cellular pathways involved, the constituent components of migratory dynamics for individual tumor cell motion have still not be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ab62320ad4bdb92a8d01e0d42164fd
https://doi.org/10.1016/j.yexcr.2004.04.001
https://doi.org/10.1016/j.yexcr.2004.04.001
Publikováno v:
Current pharmaceutical design. 18(23)
Cancer remains one of the leading causes of death in the Western world. Despite bold advances in therapeutic oncology, new drug development is infamously ineffective due to the lack of predictive in vitro models. Most patients that suffer from cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba82b32aef8611f1339e847cfc5adfc7
https://pubmed.ncbi.nlm.nih.gov/22663553
https://pubmed.ncbi.nlm.nih.gov/22663553
Publikováno v:
Current pharmaceutical design. 13(33)
Tumor cells are not only susceptible to signals from the environment, but they likewise release signal substances. It is well known that tumor cells secrete angiogenic factors - most prominently the vascular endothelial growth factor - which initiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0d8b0bf95dbb4afe693cd1003ccf1c
https://pubmed.ncbi.nlm.nih.gov/18045197
https://pubmed.ncbi.nlm.nih.gov/18045197
Publikováno v:
Medical hypotheses. 67(1)
Malignant tumors frequently release angiogenic factors, which lead to the vascularization of the tumor, a process called neoangiogenesis. This neoangiogenesis provides sufficient nourishment of the tumor when it exceeds a certain size. Recently, a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebca10630d60beca12964b7c949c7ad1
https://pubmed.ncbi.nlm.nih.gov/16516401
https://pubmed.ncbi.nlm.nih.gov/16516401