Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Theodore Kosteas"'
1
Akademický článek
The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing
Autor: Evi Goulielmaki, Maria Tsekrekou, Nikos Batsiotos, Mariana Ascensão-Ferreira, Eleftheria Ledaki, Kalliopi Stratigi, Georgia Chatzinikolaou, Pantelis Topalis, Theodore Kosteas, Janine Altmüller, Jeroen A. Demmers, Nuno L. Barbosa-Morais, George A. Garinis
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
XPA-binding protein (XAB)-2 is the human homologue of the yeast pre-mRNA splicing factor Syf1. Here the authors use an in vivo biotinylation tagging approach to show XAB2’s role in DNA repair, RNA splicing and transcription during mammalian develop
Externí odkaz: https://doaj.org/article/1b1c665c6f3c44d995dce7b93db11a4a
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2
Akademický článek
Delayed and accelerated aging share common longevity assurance mechanisms.
Autor: Björn Schumacher, Ingrid van der Pluijm, Michael J Moorhouse, Theodore Kosteas, Andria Rasile Robinson, Yousin Suh, Timo M Breit, Harry van Steeg, Laura J Niedernhofer, Wilfred van Ijcken, Andrzej Bartke, Stephen R Spindler, Jan H J Hoeijmakers, Gijsbertus T J van der Horst, George A Garinis
Publikováno v: PLoS Genetics, Vol 4, Iss 8, p e1000161 (2008)
Mutant dwarf and calorie-restricted mice benefit from healthy aging and unusually long lifespan. In contrast, mouse models for DNA repair-deficient progeroid syndromes age and die prematurely. To identify mechanisms that regulate mammalian longevity,
Externí odkaz: https://doaj.org/article/eca5369f81bc4ad7bedd0952aee33ca6
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3
The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing
Autor: Kalliopi Stratigi, Eleftheria Ledaki, Georgia Chatzinikolaou, Janine Altmüller, Nuno L. Barbosa-Morais, Nikos Batsiotos, Mariana Ascensão-Ferreira, Jeroen Demmers, George A. Garinis, Maria Tsekrekou, Evi Goulielmaki, Pantelis Topalis, Theodore Kosteas
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications, 12(1):3153. Nature Publishing Group
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f057e142e43656b0e97d65e1f8f7353
https://doaj.org/article/1b1c665c6f3c44d995dce7b93db11a4a
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6
ERCC1–XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes
Autor: George A. Garinis, Michalis Aivaliotis, John Strouboulis, Georgia Chatzinikolaou, Anna Ioannidou, Giorgio L. Papadopoulos, Zivkos Apostolou, Theodore Kosteas, Tamara Aid-Pavlidis, Ismene Karakasilioti, Maria Tsekrekou
Publikováno v: Nature Cell Biology
Inborn defects in DNA repair are associated with complex developmental disorders whose causal mechanisms are poorly understood. Using an in vivo biotinylation tagging approach in mice, we show that the nucleotide excision repair (NER) structure-speci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baea43cb95b2adbdaed166f79ceeba94
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8
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
Autor: Andrzej Bartke, Yousin Suh, Theodore Kosteas, George A. Garinis, Wilfred F. J. van IJcken, Timo M. Breit, Ingrid van der Pluijm, Stephen R. Spindler, Jan H.J. Hoeijmakers, Michael J Moorhouse, Harry van Steeg, Andria Rasile Robinson, Gijsbertus T. J. van der Horst, Björn Schumacher, Laura J. Niedernhofer
Publikováno v: PLoS Genetics, Vol 4, Iss 8, p e1000161 (2008)
PLOS Genetics, 4(8):e1000161. Public Library of Science
PLoS Genetics
PLoS Genetics (print), 4(8). Public Library of Science
Mutant dwarf and calorie-restricted mice benefit from healthy aging and unusually long lifespan. In contrast, mouse models for DNA repair-deficient progeroid syndromes age and die prematurely. To identify mechanisms that regulate mammalian longevity,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f189dee3c99661e7db0e67da197ad3e
https://doi.org/10.1371/journal.pgen.1000161
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9
Persistent Human γ-Globin Expression in Adult Transgenic Mice Following Selective Deletion of Two Repressor Elements Located 3′ to the Aγ-Globin Gene
Autor: Nicholas P. Anagnou, Maria Gazouli, Elena Katsantoni, Theodore Kosteas
Publikováno v: Blood. 108:1585-1585
Adult β-globin gene expression is tightly regulated during development and hematopoiesis. The human globin genes undergoing two developmental switches are regulated by a complex interplay between cis-acting elements and stage-specific trans-acting f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ac73535f701bff40755e3d52311e2f1
https://doi.org/10.1182/blood.v108.11.1585.1585
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