Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Theodore Koob"'
Autor:
Chang Li, Aphrodite Georgakopoulou, Gregory A. Newby, Kelcee A. Everette, Evangelos Nizamis, Kiriaki Paschoudi, Efthymia Vlachaki, Sucheol Gil, Anna K. Anderson, Theodore Koob, Lishan Huang, Hongjie Wang, Hans-Peter Kiem, David R. Liu, Evangelia Yannaki, André Lieber
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
Individuals with β-thalassemia or sickle cell disease and hereditary persistence of fetal hemoglobin (HPFH) possessing 30% fetal hemoglobin (HbF) appear to be symptom free. Here, we used a nonintegrating HDAd5/35++ vector expressing a highly efficie
Externí odkaz:
https://doaj.org/article/ad903bbc1db4441484b871ef2cf704a3
Autor:
Chang Li, Aphrodite Georgakopoulou, Gregory A Newby, Peter J Chen, Kelcee A Everette, Kiriaki Paschoudi, Efthimia Vlachaki, Sucheol Gil, Anna K Anderson, Theodore Koob, Lishan Huang, Hongjie Wang, Hans-Peter Kiem, David R Liu, Evangelia Yannaki, André Lieber
Publikováno v:
Blood.
Sickle Cell Disease (SCD) is a monogenic disease caused by a nucleotide mutation in the β-globin gene. Current gene therapy studies are mainly focused on lentivirus vector-mediated gene addition or CRISPR/Cas9-mediated fetal globin reactivation, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30af570cb24ad7ab980dfcad37b6d63b
https://doi.org/10.1182/blood.2022018252
https://doi.org/10.1182/blood.2022018252