Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Theodore Kamenecka"'
Autor:
Priscilla Chan, Lian Wu, Anahit Hovsepyan, Seda Mkhitaryan, Gevorg Karapetyan, Khalid Shah, Hiroaki Wakimoto, Theodore Kamenecka, Laura A. Solt, Jamie Cope, Rex A. Moats, Tsuyoshi Hirota, Jeremy N. Rich, Steve A. Kay
Publikováno v:
Cancer Research. 83:505-505
Glioblastoma multiforme (GBM) is the most common primary brain tumor, claiming the lives of roughly 10,000 Americans each year. Despite being the first cancer analyzed through the Cancer Genome Atlas, treatment success remains minimal, resulting aver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bcc7d278ec2cbc4894206e3bbce0555
https://doi.org/10.1158/1538-7445.am2023-505
https://doi.org/10.1158/1538-7445.am2023-505
Autor:
Laura A Solt, Ran Wang, Mohammed Amir, Sweena Chaudhari, Sean Campbell, Molly B Bassette, Amber Eliason, Mark S Sundrud, Theodore Kamenecka
Publikováno v:
The Journal of Immunology. 202:68.11-68.11
While RORγt has been well characterized as the lineage defining transcription factor for TH17 cell development, TH17 cells are not absent in Rorc-deficient mice, suggesting other factors may be required. RORα, a close family member of RORγt, is al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac6e178ce1e9f2c62cbcbadc7e9e5c08
https://doi.org/10.4049/jimmunol.202.supp.68.11
https://doi.org/10.4049/jimmunol.202.supp.68.11
Publikováno v:
The Journal of Immunology. 202:183.10-183.10
The REV-ERBs (REV-ERBα and REV-ERBβ) are members of the nuclear receptor superfamily of ligand-regulated transcription factors and owing to their ability to recruit corepressor, act as transcriptional repressors. The REV-ERBs have well-established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33a7f13ca4e40f69f306340f42c5afd0
https://doi.org/10.4049/jimmunol.202.supp.183.10
https://doi.org/10.4049/jimmunol.202.supp.183.10
Publikováno v:
The Journal of Immunology. 190:212.4-212.4
The nuclear receptor RORγ has been shown to play an essential role in the development of Th17 cells. Previously, it was reported that the potent and selective RORγ inverse agonist SR2211 was effective at modulating RORγ activity in cell culture. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49c590d7ea1857215a4bcc0b2bb28c2
https://doi.org/10.4049/jimmunol.190.supp.212.4
https://doi.org/10.4049/jimmunol.190.supp.212.4