Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Theodore J. Nusbaum"'
Autor:
Michael R. Rose, Kelly A. Beckman, Adam K. Chippindale, Theodore J. Nusbaum, Margaret A. Archer, John P. Phelan
Publikováno v:
Evolution. 57:527-535
We provide evidence from comparisons of populations of Drosophila that evolutionary correlations between longevity and stress resistance break down over the course of laboratory evolution. Using 15 distinct evolutionary regimes, we created 75 populat
Publikováno v:
Mueller, LD; Nusbaum, TJ; & Rose, MR. (1995). The Gompertz equation as a predictive tool in demography. Experimental Gerontology, 30(6), 553-569. doi: 10.1016/0531-5565(95)00029-1. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1xw3w5r4
The Gompertz demographic model describes rates of aging and age-independent mortality with the parameters α and A, respectively. Estimates of these parameters have traditionally been based on the assumption that mortality rates are constant over sho
Autor:
Michael R. Rose, Theodore J. Nusbaum
Publikováno v:
The FASEB Journal. 8:925-928
The postponement of human aging is a long-standing aspiration in many cultures, particularly non-Western ones. Renewed interest in this goal is now being shown within the biomedical research context. This interest has probably arisen because several
Publikováno v:
Science. 260:1567-1569
Autor:
Theodore J. Nusbaum, Michael R. Rose
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 54(5)
There are parallels between the effects of laboratory selection and nutritional manipulation on the expression of lifespan and other fitness-related characters in Drosophila melanogaster. However, little is known about the effects of laboratory selec
Publikováno v:
Nusbaum, TJ; Mueller, LD; & Rose, MR. (1996). Evolutionary patterns among measures of aging. Experimental Gerontology, 31(4), 507-516. doi: 10.1016/0531-5565(96)00002-2. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7vc1z818
Maximum lifespan has been one of the most common aging measures in comparative studies, while the Gompertz model has recently attracted both proponents and critics of its capacity to adequately describe the acceleration of mortality in the oldest age
Autor:
Michael R. Rose, Theodore J. Nusbaum
Publikováno v:
Comparative biochemistry and physiology. Physiology. 109(1)
Flies of the genus Drosophila, particularly D. melanogaster, have been mainstays of biological research on aging for more than 80 years. However, what was striking for most of those years was how little concrete progress was made on the problem of ag
Autor:
Theodore J. Nusbaum
Publikováno v:
The Quarterly Review of Biology. 71:448-448
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