Zobrazeno 1 - 10
of 487
pro vyhledávání: '"Theodore J, Price"'
Autor:
Bradford E. Hall, Khadijah Mazhar, Emma Macdonald, Margaret Cassidy, Megan Doty, Christian Judkins, Anita Terse, Stephanie Shiers, Saber Tadros, Sijung Yun, Michael D. Burton, Theodore J. Price, Ashok B. Kulkarni
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Autoimmune diseases such as rheumatoid arthritis (RA) can promote states of chronic inflammation with accompanying tissue destruction and pain. RA can cause inflammatory synovitis in peripheral joints, particularly within the hands and feet,
Externí odkaz:
https://doaj.org/article/f93cc78f997a48deb8769585b76ceaa5
Autor:
Kaitlyn M. Malley, Andrea D. Ruiz, Michael J. Darrow, Tanya Danaphongse, Stephanie Shiers, Fatima N. Ahmad, Clareth Mota-Beltran, Benjamin T. Stanislav, Theodore J. Price, Robert L. Rennaker, Michael P. Kilgard, Seth A. Hays
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Impairments in somatosensory function are a common and often debilitating consequence of neurological injury, with few effective interventions. Building on success in rehabilitation for motor dysfunction, the delivery of vagus nerve stimulat
Externí odkaz:
https://doaj.org/article/24da13ae2b19424f926fad02a1a35c84
Autor:
George T. Naratadam, Jennifer Mecklenburg, Sergey A. Shein, Yi Zou, Zhao Lai, Alexei V. Tumanov, Theodore J. Price, Armen N. Akopian
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract This study investigated the time course of gene expression changes during the progression of persistent painful neuropathy caused by paclitaxel (PTX) in male and female mouse hindpaws and dorsal root ganglia (DRG). Bulk RNA-seq was used to e
Externí odkaz:
https://doaj.org/article/2879d39e45dd414fbd289733bac85680
Autor:
Cynthia M. Arokiaraj, Michael J. Leone, Michael Kleyman, Alexander Chamessian, Myung-Chul Noh, BaDoi N. Phan, Bettega C. Lopes, Kelly A. Corrigan, Vijay Kiran Cherupally, Deepika Yeramosu, Michael E. Franusich, Riya Podder, Sumitra Lele, Stephanie Shiers, Byungsoo Kang, Meaghan M. Kennedy, Viola Chen, Ziheng Chen, Hansruedi Mathys, Richard P. Dum, David A. Lewis, Yawar Qadri, Theodore J. Price, Andreas R. Pfenning, Rebecca P. Seal
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114876- (2024)
Summary: Key mechanisms underlying chronic pain occur within the dorsal horn. Genome-wide association studies (GWASs) have identified genetic variants predisposed to chronic pain. However, most of these variants lie within regulatory non-coding regio
Externí odkaz:
https://doaj.org/article/3f588436835441efb2ed009e8dffb3e7
Autor:
Anil Kumar Kalia, Corinna Rösseler, Rafael Granja-Vazquez, Ayesha Ahmad, Joseph J. Pancrazio, Anika Neureiter, Mei Zhang, Daniel Sauter, Irina Vetter, Asa Andersson, Gregory Dussor, Theodore J. Price, Benedict J. Kolber, Vincent Truong, Patrick Walsh, Angelika Lampert
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract Background Human induced pluripotent stem cell (iPSC)-derived peripheral sensory neurons present a valuable tool to model human diseases and are a source for applications in drug discovery and regenerative medicine. Clinically, peripheral se
Externí odkaz:
https://doaj.org/article/64b0342489ca43859d062555e3986dc2
Autor:
Eric T. David, Muhammad Saad Yousuf, Hao-Ruei Mei, Ashita Jain, Sharada Krishnagiri, Hajira Elahi, Rupali Venkatesan, Kolluru D. Srikanth, Gregory Dussor, Matthew B. Dalva, Theodore J. Price
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107284- (2024)
Ephrin-B-EphB signaling can promote pain through ligand-receptor interactions between peripheral cells, like immune cells expressing ephrin-Bs, and EphB receptors expressed by DRG neurons. Previous studies have shown increased ephrin-B2 expression in
Externí odkaz:
https://doaj.org/article/1917a806dbe74c77aa586879d6f19d8e
Autor:
Hyun-Woong Kim, Jessica Kovar, Jesper Singh Bajwa, Yasir Mian, Ayesha Ahmad, Marisol Mancilla Moreno, Theodore J. Price, Yune Sang Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract A growing body of literature has reported the relationship between music and language, particularly between individual differences in perceptual rhythm skill and grammar competency in children. Here, we investigated whether motoric aspects o
Externí odkaz:
https://doaj.org/article/1bf22960a4bb47648e7a3ac1b473c63e
Autor:
Úrzula Franco-Enzástiga, Keerthana Natarajan, Eric T. David, Krish Patel, Abhira Ravirala, Theodore J. Price
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108808- (2024)
Summary: Type I interferons (IFNs) increase the excitability of dorsal root ganglia (DRGs) neurons via MNK-eIF4E signaling to promote pain sensitization in mice. Activation of stimulator of interferon response cGAMP interactor 1 (STING) signaling is
Externí odkaz:
https://doaj.org/article/688dcb06c1d44b62b6ff069f2810cfa6
Autor:
Maximilian Zeidler, Diana Tavares-Ferreira, Jackson Brougher, Theodore J. Price, Michaela Kress
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108525- (2023)
Summary: Non-coding RNAs (ncRNAs) are pivotal in gene regulation during development and disease. MicroRNAs have been extensively studied in neurogenesis. However, limited knowledge exists about the developmental signatures of other ncRNA species in s
Externí odkaz:
https://doaj.org/article/6b84e85d63374196846254dd6b31d08a
Autor:
Bianca N. Mason, Shayne N. Hassler, Kathryn DeFea, Scott Boitano, Josef Vagner, Theodore J. Price, Greg Dussor
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Migraine is a severely debilitating disorder that affects millions of people worldwide. Studies have indicated that activation of protease-activated receptor-2 (PAR2) in the dura mater causes headache responses in preclinical mode
Externí odkaz:
https://doaj.org/article/e59629c7f6954a7284df0a868cea63a5