Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Theodore G. Wright"'
Autor:
Xiaohao Yao, Y. Tony Ip, Ken-ichi Kariya, Junhao Mao, Lan Xu, Satoshi Kaneko, Xiaochu Chen, Theodore G. Wright, Peiyuan Lu, Mihir Rajurkar
Publikováno v:
Proceedings of the National Academy of Sciences. 108:11127-11132
The level of TGF-β/bone morphogenetic protein (BMP) signaling through Smad is tightly regulated to ensure proper embryonic patterning and homeostasis. Here we show that Smad activation by TGF-β/BMP is blocked by a highly conserved phosphorylation e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139895ccdeec5ba9c3f7c5f2d5a11d4e
https://doi.org/10.1073/pnas.1104128108
https://doi.org/10.1073/pnas.1104128108
Autor:
Meenakshi Sundaram, Yuwei Wang, Zhibin Ning, Zemin Yao, Daniel Figeys, Shumei Zhong, Fangjun Wang, Theodore G. Wright, Weimin Hou, Hu Zhou
Despite their importance in many biological processes, membrane proteins are underrepresented in proteomic analysis because of their poor solubility (hydrophobicity) and often low abundance. We describe a novel approach for the identification of plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74828f3d69f1dc93a96c49abce1c7c8
https://europepmc.org/articles/PMC3205877/
https://europepmc.org/articles/PMC3205877/
Autor:
Nabil G. Seidah, Janice Mayne, Fred Elisma, Nicholas J. Denis, Maroun Bou Khalil, Annik Prat, Michel Chrétien, Alia Busuttil, Heather Palmer-Smith, Daniel Figeys, Theodore G. Wright
Publikováno v:
Journal of proteome research. 10(4)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in cholesterol homeostasis, mediating degradation of the liver low-density lipoprotein receptor (LDLR). In fact, gain- and loss-of-function PCSK9 variations in human popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0014eb91b7b00eb9c014a6cfda2b7b
https://pubmed.ncbi.nlm.nih.gov/21332221
https://pubmed.ncbi.nlm.nih.gov/21332221
Autor:
Houjiang Zhou, Nicholas J. Denis, Fred Elisma, Hu Zhou, Ruijun Tian, Hanfa Zou, Theodore G. Wright, Weimin Hou, Daniel Figeys
Publikováno v:
Journal of proteome research. 9(3)
Protein phosphorylation is an important post-translational modification involved in the regulation of many cellular processes. Mass spectrometry has been successfully used to identify protein phosphorylation in specific pathways and for global phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc87b9fce7bbd79ae6f9121422a5f31
https://pubmed.ncbi.nlm.nih.gov/20067319
https://pubmed.ncbi.nlm.nih.gov/20067319
Autor:
Jonathan H. Foley, Vinay K. Singh, John J. Li, Bruce E. Elliott, Theodore G. Wright, Zongchao Jia, Frederick W. Miller
Publikováno v:
International journal of cancer. 125(5)
Invasive human breast carcinomas frequently coexpress increased hepatocyte growth factor (HGF) and its receptor Met, suggesting that establishment of an autocrine HGF loop is important in malignant disease. This study examines the expression patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7595652ec898844ab9512661035935e
https://pubmed.ncbi.nlm.nih.gov/19415747
https://pubmed.ncbi.nlm.nih.gov/19415747
Publikováno v:
The Journal of biological chemistry. 279(31)
Overexpression of hepatocyte growth factor (HGF) and its receptor Met often occurs in carcinoma cells, leading to establishment of an HGF/Met autocrine loop. Therefore, disruption of the HGF/Met autocrine loop may lead to down-regulation of tumorigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec02dc5e6d59481e2262acde2ae19765
https://pubmed.ncbi.nlm.nih.gov/15161915
https://pubmed.ncbi.nlm.nih.gov/15161915
Publikováno v:
The Journal of biological chemistry. 279(4)
During lipoprotein(a) (Lp(a)) assembly, non-covalent interactions between apolipoprotein(a) (apo(a)) and low density lipoprotein precede specific disulfide bond formation. Studies have shown that the non-covalent step involves an interaction between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c80624f27988ef3ab5829c14c88e5cf
https://pubmed.ncbi.nlm.nih.gov/14581473
https://pubmed.ncbi.nlm.nih.gov/14581473
Autor:
Kaneko, Satoshi, Xiaochu Chen, Peiyuan Lu, Xiaohao Yao, Wright, Theodore G., Rajurkar, Mihir, Kariya, Ken-ichi, Junhao Mao, Ip, Y. Tony, Lan Xu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/5/2011, Vol. 108 Issue 27, p11127-11132, 6p
Autor:
Henry Allen Castle
This is a comprehensive history of the beginnings, trials, and flourishing of Plainville Connecticut. As Gertrude Castle Nystrom wrote in the preface to her father's book, “This history of the beginnings of Plainville, Connecticut, covering the per