Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Theodore G. Sarphie"'
Autor:
Nympha B. D'Souza, Mariana Nikolova-Karakashian, Ion V. Deaciuc, Theodore G. Sarphie, Craig J. McClain, Willem J.S. de Villiers, Daniell B. Hill
Publikováno v:
Hepatology Research. 24:192-204
The purpose of this study was to further characterize Fas-mediated liver apoptosis. We investigated whether Fas-mediated apoptosis in the liver requires induction of apoptosis-related regulators and whether Kupffer cells play a role in this process.
Autor:
Ravshan Burikhanov, Theodore G. Sarphie, Craig J. McClain, Nympha B. D'Souza, Willem J.S. de Villiers, Daniell B. Hill, Ion V. Deaciuc
Publikováno v:
Alcoholism: Clinical and Experimental Research. 25:935-943
Background: The mechanisms of liver sensitization by alcohol to Gram-negative bacterial lipopolysaccharide (LPS) remain elusive. The purpose of this study was two-fold: (1) to test the hypothesis that alcohol-enhanced liver apoptosis may be a sensiti
Autor:
Franco Fortunato, Theodore G. Sarphie, Nympha B. D'Souza, Daniell B. Hill, Ion V. Deaciuc, Craig J. McClain
Publikováno v:
Hepatology Research. 19:85-97
The purpose of this study was to determine if a correlation exists between alcohol-induced liver sinusoidal endothelial cell (SEC) dysfunction and alcohol-induced augmented liver apoptosis in the mouse. Mice were fed an alcohol-containing liquid diet
Autor:
Zhuo Tao, Frank W. Smart, Parakat Vijayagopal, Theodore G. Sarphie, D. Luke Glancy, Julio E. Figueroa
Publikováno v:
Atherosclerosis. 143:135-144
Hypoxia and hypoxia/reoxygenation are known to affect vascular smooth muscle cell physiology. In this study, we first investigated proteoglycan synthesis by human aortic smooth muscle cells exposed to normoxia, hypoxia, or hypoxia/reoxygenation. We t
Autor:
Craig J. McClain, Ion V. Deaciuc, Theodore G. Sarphie, Nympha B. D'Souza, Daniell B. Hill, Jack Schmidt
Publikováno v:
Journal of Hepatology. 30:213-221
Background/Aims: Functional and morphological alterations of the hepatic sinusoidal endothelial cell occur in several models of experimental liver injury and in clinical settings. The causes of these alterations are multiple. The aim of this study wa
Publikováno v:
Alcoholism: Clinical and Experimental Research. 20:973-979
Electron microscopic appearance of the liver sinusoid was examined in rats fed alcohol chronically in a complete liquid diet or in sucrose-containing drinking water. The animals were kept on liquid diet (+/- alcohol) for 14 weeks or on sucrose-contai
Publikováno v:
Hepatology (Baltimore, Md.). 23(4)
Scanning and transmission electron-microscopic examination of the rat liver sinusoid was performed in this study after in vivo treatment of rats with gram-negative bacterial lipopolysaccharide (LPS, 1 mg/Kg(-1) body weight), with or without pretreatm
Publikováno v:
Alcoholism, clinical and experimental research. 19(2)
Transmission and scanning electron microscopic studies were performed on the liver sinusoid, with emphasis on sinusoidal endothelial cells, in rats fed a liquid diet containing either alcohol or dextrin (control) for 14 weeks. Animals were also treat