Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Theodore E. Whitmore"'
Autor:
Scott R. Presnell, Deborah L. Smith, Rolf E. Kuestner, Theodore E. Whitmore, Philip J. Horner, Theo D. Palmer, Emma E. Moore, Ursula Garrigues, Angele Guilbot, Eric LeGuern, Teresa Gilbert, Lena Yao
Publikováno v:
Neuromuscular Disorders. 12:141-150
IL-17B is a recently identified homolog of IL-17. Northern analysis revealed that IL-17B mRNA is expressed at very high levels in spinal cord and at much lower and more variable levels in trachea, prostate, lung, small intestine, testes, adrenal, and
Autor:
Wenfeng Xu, Maribeth A. Eagan, Ty Brender, Mark F. Maurer, Melanie K. Kuechle, Darrell C. Conklin, Angelika Grossmann, Yasmin A. Chandrasekher, Lena Yao, Laura J. Jelinek, Susan Carollo, Hal Blumberg, Kim Waggie, James D. Kelly, Cindy A. Sprecher, Julia Parrish-Novak, Theodore E. Whitmore, Betty A. Haldeman, Karen L. Madden, Beverly A. Dale, Don Foster, Donna E. Prunkard, Harald S. Haugen, Shannon L. Sexson, Angie Hammond, James W. West
Publikováno v:
Cell. 104(1):9-19
A structural, profile-based algorithm was used to identify interleukin 20 (IL-20), a novel IL-10 homolog. Chromosomal localization of IL-20 led to the discovery of an IL-10 family cytokine cluster. Overexpression of IL-20 in transgenic (TG) mice caus
Autor:
Don Foster, Mark D. Heipel, Theodore E. Whitmore, Stacey R. Dillon, Margaret D. Moore, Susan Bort, Jane A. Gross, Cindy A. Sprecher, Karen L. Madden, Philippa J. Webster, Fenella C. Raymond, Janet V. Johnston, Cameron S. Brandt, Andrew Nelson, Teresa Gilbert, Kevin Hambly, Mark F. Maurer, Darrell C. Conklin, Sara K. Schrader, Francis J. Grant, Rick D. Holly, Andrew Ching, Wenfeng Xu, Sherri Mudri, Kenneth Kaushansky, Faith Shiota, Scott R. Presnell, Lena Yao, Angie Hammond, Catherine Lofton-Day, Steve K. Burkhead, Julia Parrish-Novak, Chris Clegg, Joseph L. Kuijper, Jon Berry, Deborah L. Smith, Janet M. Kramer, James A. West
Publikováno v:
Nature. 408:57-63
Cytokines are important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. Here we have identified a class I cytokine receptor that is selectively expressed in lymphoid tissues and is capable of signal
Autor:
Mark F. Maurer, Darrell C. Conklin, Theodore E. Whitmore, Susan D. Holderman, Andrew L. Feldhaus
Publikováno v:
Gene. 249:91-98
The sequence of the ubiquitin protein is highly conserved between species and has facilitated the cloning of numerous ubiquitin-like proteins. In the present study, we report the cloning of the cDNA for human ubiquilin 3 (UBQLN3). The deduced amino a
Autor:
Mark F. Maurer, James L. Holloway, Andrew L. Feldhaus, Kimberly E. Shoemaker, Theodore E. Whitmore
Publikováno v:
Gene. 245:103-108
The cystatin superfamily of cysteine proteinase inhibitors consists of three major families. In the present study, we report the cloning of the cDNA for mouse cystatin T, which is related to family 2 cystatins. The deduced amino acid sequence of cyst
Autor:
C.E. Lofton-Day, Theodore E. Whitmore, T.J. Quinton, L. Chen, John B. Vincent, S. Lok, J.L. Holloway, Stephen W. Scherer, M.F. Maurer
Publikováno v:
Cytogenetic and Genome Research. 90:47-52
Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Recently, it has been discussed that secretin deficiency may be implicated in autistic syndrome, suggesting that the hormone could have a neuroendoc
Autor:
David W. Taft, Kenneth B. Lewis, Michael Nehls, Mark F. Maurer, Darrell C. Conklin, Kathleen M. Walker, Lennie H. Chen, Deborah L. Smith, Debra G. Gilbertson, Sigrid Wattler, Theodore E. Whitmore
Publikováno v:
Genomics. 62:477-482
Based on searches of EST databases for signal sequences and amphipathic helices, we have identified and cloned an angiopoietin-like gene, ANGPTL3. Multiple tissue Northern blots show that ANGPTL3 is expressed principally in the liver. ANGPTL3 is expr
Autor:
Si Lok, Darrell C. Conklin, Theodore E. Whitmore, Stephen R. Jaspers, Catherine Lofton-Day, Betty A. Haldeman, Andrew Ching
Publikováno v:
Genomics. 60:50-56
A new member of the insulin gene superfamily (INSL5) was identified by searching EST databases for the presence of the conserved insulin B-chain cysteine motif. Human and murine INSL5 are both polypeptides of 135 amino acids, matching the classical s
Publikováno v:
Biochemical and Biophysical Research Communications. 219:405-411
Neutrophil migration and activation are the cornerstones of the acute inflammatory response. Interleukin-8 triggers several functions of neutrophils in host defense: chemotaxis, degranulation and enzyme release, and superoxide production. Interleukin
Autor:
Amelia Peterson, Ashley Eastham, Ted Holzman, Peter S. Nelson, Martin W. McIntosh, Adrian Ozinsky, Lynn M. Amon, Theodore E. Whitmore, Daniel Martin
Publikováno v:
Journal of proteome research. 11(5)
In an attempt to identify prostate cancer biomarkers with greater diagnostic and prognostic capabilities, we have developed an integrative proteomic discovery workflow focused on N-linked glycoproteins that refines the target selection process. In th