Výsledky vyhledávání - "Theodore Danoff"

A New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal Men

Autor: Theodore Danoff, Ronald S. Swerdloff, Jed Kaminetsky, James Longstreth, Marc Gittelman, Robert E Dudley, Christina Wang, William B. White

Publikováno v: The Journal of Clinical Endocrinology and Metabolism

Context A novel formulation of oral testosterone (T) undecanoate (TU) was evaluated in a phase 3 clinical trial. Objective Determine efficacy, short-term safety, and alignment of new oral TU formulation with current US approval standards for T replac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9aba258a94b2f48af0e22fcc3ce811
https://doi.org/10.1210/clinem/dgaa238

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RATIONALE AND DESIGN OF THE PRIMEX TRIAL: A STUDY OF 2 DOSES OF ORAL CXA-10 IN PULMONARY ARTERIAL HYPERTENSION (PAH)

Autor: Mardi Gomberg-Maitland, Raymond L. Benza, David B. Badesch, Theodore Danoff, Steven M. Kawut, Mark T. Gladwin, Marc A. Simon, Gerald O. Brien, Roberto Machado, J. Simon R. Gibbs, Ronald J. Oudiz, Anna R. Hemnes

Publikováno v: Chest. 158:A2246-A2248

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae14eb2778ec65580944de2e54f6aac5
https://doi.org/10.1016/j.chest.2020.08.1914

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SAT-044 Treatment of Hypogonadal Men with a New Oral Testosterone Undecanoate (TU) Formulation Improves Psychosexual, Well-Being and Body Composition and Bone Density Parameters

Autor: Ronald S. Swerdloff, Robert E Dudley, Adrian S. Dobs, Theodore Danoff, John K. Amory, Christina Wang

Publikováno v: Journal of the Endocrine Society

Introduction and Objective: A new, first-in-class oral testosterone (T) replacement therapy product [T-undecanoate (TU) capsules] was recently approved by FDA to treat hypogonadal men. Clinical trials were conducted to evaluate, in part, the impact o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d5e4ae1862a725c2250377a366130a
http://europepmc.org/articles/PMC7368366

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Accurate measurement of androgen after androgen esters: problems created by ex vivo esterase effects and LC‐MS/MS interference

Autor: Theodore Danoff, Ronald S. Swerdloff, F. Bai, Jonas Čeponis, Andrew Leung, James Longstreth, Robert E Dudley, Laura Hull, Christina Wang

Publikováno v: Andrology

Background Ex vivo androgen prodrug conversion by blood esterases after oral androgen ester administration may result in an overestimation of the measured blood androgens. Objective We investigated whether blood collection tubes with esterase inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d9b1583a2ab74e4e44f6b909c5d3a4
http://europepmc.org/articles/PMC6519384

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SUN-227 Monitoring Testosterone (T) Levels in Men Receiving Oral Testosterone Undecanoate (TU): Challenges Due to Post-Collection Conversion of TU-to-T and a Path Forward

Autor: Ronald S. Swerdloff, Theodore Danoff, Christina Wang, James Longstreth, Robert E Dudley

Publikováno v: Journal of the Endocrine Society

Introduction: Measuring T levels, in addition to monitoring symptoms, during T replacement therapy is critical to guide dosing decisions. T levels in blood samples from men receiving oral TU can be elevated substantially above actual circulating T le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b301210788cb63738cb6a28c00e0b990
https://doi.org/10.1210/js.2019-sun-227

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MP58-17 MONITORING TESTOSTERONE (T) LEVELS IN MEN RECEIVING ORAL TESTOSTERONE UNDECANOATE (TU): DEALING WITH POST-COLLECTION CONVERSION OF TU TO T

Autor: Ronald S. Swerdloff, Jed Kaminetsky, Marc Gittelman, James Longstreth, Theodore Danoff, Robert E Dudley

Publikováno v: Journal of Urology. 201

INTRODUCTION AND OBJECTIVES:Measuring T levels during T replacement therapy is critical to guide dosing decisions. Post-collection conversion of TU to T by esterases in blood from men receiving ora...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4db5157f29dd3e3db59e9f00c6c8f48f
https://doi.org/10.1097/01.ju.0000556709.56920.43

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PD26-10 TREATMENT OF HYPOGONADAL MEN WITH ORAL TESTOSTERONE UNDECANOATE (TU) IMPROVES PSYCHO-SEXUAL, WELL-BEING AND BODY COMPOSITION PARAMETERS

Autor: Ronald S. Swerdloff, Stanton C. Honig, Kaminetsky Jed, Theodore Danoff, Marc Gittelman, Robert E Dudley

Publikováno v: The Journal of Urology. 203:e547

INTRODUCTION AND OBJECTIVE:A new, first-in-class oral testosterone (T) replacement therapy product [T-undecanoate (TU) capsules] was recently approved by FDA to treat appropriate hypogonadal men. T...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e85c403139b76c05ff90aafc01c3e9ee
https://doi.org/10.1097/ju.0000000000000883.010

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Book Review UpToDate in Nephrology and Hypertension Edited by Burton D. Rose; System designed by Joseph Rush. Eight diskettes with manual, 44 pp. System needed: Apple Macintosh with minimum 14 MB free hard-disk space. Wellesley, Mass., Carol Peckham, 1992. $495 (individual); $250 (partner); $135 (fellow); $1550 (institution)

Autor: Theodore Danoff

Publikováno v: New England Journal of Medicine. 329:284-284

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6d6efc035c463f49afd2498639d2a63
https://doi.org/10.1056/nejm199307223290421

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