Výsledky vyhledávání - "Theodore D. Kessis"

Human Papillomavirus Investigation of Patients with Cervical Intraepithelial Neoplasia 3, Some of Whom Progressed to Invasive Cancer

Autor: Farida Shah, Ronald W. Jones, Jean W. Gupta, Keerti V. Shah, Darryl Shibata, Theodore D. Kessis

Publikováno v: International Journal of Gynecological Pathology. 15:127-130

The major objective of the study was to determine if the contrasting frequencies (1.5% vs. 22%) of progression of cervical intraepithelial neoplasia (CIN) 3 lesions to invasive cervical carcinoma in two groups of patients in a previously published st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14af9cfb77c43e1a34d6c43c2b5828ac
https://doi.org/10.1097/00004347-199604000-00006

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Functional Consequences of Directed Mutations in Human Papillomavirus E6 Proteins: Abrogation of p53-Mediated Cell Cycle Arrest Correlates with p53 Binding and Degradation in Vitro

Autor: Lora Hedrick, Theodore D. Kessis, Sung M. Han, Kathleen R. Cho, Alex W. Chen, Robbert J. C. Slebos

Publikováno v: Virology. 208:111-120

Clinical and epidemiological studies have implicated the involvement of human papillomavirus (HPV) infection in cervical tumorigenesis. We have previously shown that expression of high-risk (HPV16) E6 can abrogate an important cell cycle checkpoint m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60450a920d10cdf3a1affff18833ba3
https://doi.org/10.1006/viro.1995.1134

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p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein

Autor: Beverly Plunkett, Robbert J. C. Slebos, Bart O. Williams, Kathleen R. Cho, Michael B. Kastan, Mann H. Lee, Tyler Jacks, Lora Hedrick, Theodore D. Kessis

Publikováno v: Proceedings of the National Academy of Sciences. 91:5320-5324

The cell cycle regulatory tumor suppressor proteins p53 and pRB are targeted for inactivation by several tumor viruses, including the high-risk types of human papillomaviruses (HPVs) via interactions of the HPV E6 and E7 oncoproteins with p53 and pRB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60beeff783d41513bb398b763726ff7
https://doi.org/10.1073/pnas.91.12.5320

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Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage

Autor: Beverly Plunkett, William G. Nelson, Michael B. Kastan, Sung M. Han, Theodore D. Kessis, Robert J. Slebos, Lora Hedrick, Attila T. Lorincz, Kathleen R. Cho

Publikováno v: Proceedings of the National Academy of Sciences. 90:3988-3992

Infection with certain types of human papillomaviruses (HPV) is highly associated with carcinomas of the human uterine cervix. However, HPV infection alone does not appear to be sufficient for the process of malignant transformation, suggesting the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3529410a6a5adf9f971477aa6b21cd8
https://doi.org/10.1073/pnas.90.9.3988

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Polymerase chain reaction identification of human papillomavirus DNA in CO 2 laser plume from recurrent respiratory papillomatosis

Autor: Keerti V. Shah, Phoebe Mounts, Haskins K. Kashima, Theodore D. Kessis

Publikováno v: Otolaryngology–Head and Neck Surgery. 104:191-195

Human papillomavirus (HPV) DNA was identified in the plume produced during CO2 laser vaporization of respiratory tract papillomata. The plume produced from CO2 vaporization was collected on Gelfoam pledgets that were affixed to suction tips evacuatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0856cfb149e1dac8fcbd99e867618996
https://doi.org/10.1177/019459989110400206

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p53 mutations and clonality in vulvar carcinomas and squamous hyperplasias: evidence suggesting that squamous hyperplasias do not serve as direct precursors of human papillomavirus-negative vulvar carcinomas

Autor: Neena F Thomas, Lora Hedrick, Theodore D Kessis, Edward J. Wilkinson, Kathleen R. Cho, Young-Tak Kim

Publikováno v: Human pathology. 27(4)

Previous studies of vulvar carcinomas have shown two distinct subsets with respect to several clinicopathologic features. In younger women, the tumors are frequently human papillomavirus (HPV) positive, are usually of basaloid or warty histology, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5d5ff0562acd37db6eb8521c0bb572
https://pubmed.ncbi.nlm.nih.gov/8617483

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Probable nonpapillomavirus etiology of squamous cell carcinoma of the vulva in older women: a clinicopathologic study using in situ hybridization and polymerase chain reaction

Autor: Jong Sup Park, Toshihiko Toki, Richard W. Daniel, Theodore D. Kessis, Robert J. Kurman, Keerti V. Shah

Publikováno v: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 10(2)

A clinical, pathologic, and molecular virologic analysis of 30 cases of invasive squamous cell carcinoma of the vulva was undertaken to investigate the relationship of human papillomavirus (HPV) to this neoplasm. The presence of the virus was detecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c638002d099860ae13f291d93bc0804
https://pubmed.ncbi.nlm.nih.gov/1851729

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Human papillomavirus in squamous cell carcinoma, leukoplakia, lichen planus, and clinically normal epithelium of the oral cavity

Autor: Keerti V. Shah, E. M. De Villiers, L. S. Levin, Mark J Kutcher, Haskins K. Kashima, Theodore D. Kessis

Publikováno v: The Annals of otology, rhinology, and laryngology. 99(1)

Tissue specimens of carcinoma, leukoplakia, and clinically normal epithelium obtained at sites separate from the lesions were examined for the presence of human papillomavirus (HPV). Twenty-two paraffinized specimens of previously diagnosed oral lich

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71aa02a1bc2e999c9c80639f4d3e8160
https://pubmed.ncbi.nlm.nih.gov/2153015

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