Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Theodore C. Simon"'
Autor:
Hanna Haveri, Lora J. Staloch, Joyce K. Divine, Markku Heikinheimo, Christina Jacobsen, Theodore C. Simon, David B. Wilson
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 287:G1086-G1099
Transcriptional regulation by GATA-4, GATA-5, and GATA-6 in intestine and liver was explored using a transgene constructed from the proximal promoter of the rat liver fatty acid binding protein gene (Fabpl). An immunohistochemical survey detected GAT
Publikováno v:
Kidney International. 65(6):2212-2222
Matrilysin (MMP-7) expression in renal tubular damage: Association with Wnt4 . Background Matrilysin, a secreted matrix metalloproteinase and target gene of Wnt signaling, functions in epithelial repair and host defense, but no role in renal injury h
Autor:
Saulo Klahr, Keith A. Hruska, Theodore C. Simon, Jeremiah J. Morrissey, Song Wang, Frank Strebeck, Helen Liapis, Lala R. Chaudhary, Qing Chen
Publikováno v:
Kidney International. 63:2037-2049
Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy.BackgroundBone morphogenic protein-7 (BMP-7), an essential developmental renal morphogen, is a secreted differentiation factor of the adult collecting duct. It activates rec
Publikováno v:
American Journal of Physiology-Renal Physiology. 284:F653-F662
C-type natriuretic peptide (CNP) regulates salt excretion, vascular tone, and fibroblast proliferation and activation. CNP inhibits fibroblast activation in vitro and fibrosis in vivo, but endogenous CNP gene ( Nppc) expression during tissue fibrosis
Publikováno v:
Genomics. 81:58-66
The homeodomain transcription factor EMX2 is critical for central nervous system and urogenital development. In addition, EMX2 maps to a region of allelic deletion corresponding to a putative endometrial tumor suppressor at 10q26. We now report anoth
Publikováno v:
Journal of Biological Chemistry. 272:10652-10663
A 35-nucleotide sequence in the liver fatty acid-binding protein gene (Fabpl) has been identified that interacts with nuclear proteins present in adult mouse liver, kidney, stomach, small intestine, and colon. The binding site consists of a direct he
Publikováno v:
Journal of Biological Chemistry. 268:18345-18358
Axial pattern formation is sustained in the mammalian gut epithelium despite rapid and continuous renewal of its four principal cell lineages. The mouse and rat liver fatty acid-binding protein (L-FABP) genes (Fabpl) represent an excellent model for
Autor:
Hanna Haveri, Markku Heikinheimo, Theodore C. Simon, Joyce K. Divine, Christopher W. Rowley, Lora J. Staloch
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 291(2)
GATA-4, GATA-5, and GATA-6 are endodermal zinc-finger transcription factors that activate numerous enterocytic genes. GATA-4 and GATA-6 but not GATA-5 are present in adult murine small intestinal enterocytes, and we now report the simultaneous presen
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 290(3)
Hepatic nuclear factor (HNF)-4alpha and HNF-1alpha are key endodermal transcriptional regulators that physically and functionally interact. HNF-4alpha and HNF-1alpha cooperatively activate genes with binding sites for both factors, whereas suppressiv
Publikováno v:
Biochimica et biophysica acta. 1731(3)
A transgene constructed from the rat liver fatty acid binding protein gene (Fabp1) promoter is active in all murine small intestinal crypt and villus epithelial cells. Coincident Cdx and C/EBP transcription factor binding sites were identified spanni