Zobrazeno 1 - 10
of 473
pro vyhledávání: '"Theodore A, Slotkin"'
Autor:
Kay Palopoli-Trojani, Stephen L. Schmidt, Karley D. Baringer, Theodore A. Slotkin, Jennifer J. Peters, Dennis A. Turner, Warren M. Grill
Publikováno v:
Brain Stimulation, Vol 16, Iss 6, Pp 1630-1642 (2023)
Background: Traditional deep brain stimulation (DBS) at fixed regular frequencies (>100 Hz) is effective in treating motor symptoms of Parkinson's disease (PD). Temporally non-regular patterns of DBS are a new parameter space that may help increase e
Externí odkaz:
https://doaj.org/article/fd27b5d74b0a4aa7aea40f920da1dea5
Autor:
Andrew B. Hawkey, Janequia Evans, Zade R. Holloway, Erica Pippen, Olivia Jarrett, Bruny Kenou, Theodore A. Slotkin, Frederic J. Seidler, Edward D. Levin
Publikováno v:
Birth Defects Research. 115:357-370
Human exposures to organophosphate flame retardants result from their use as additives in numerous consumer products. These agents are replacements for brominated flame retardants but have not yet faced similar scrutiny for developmental neurotoxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd9797506a74935dc7e1e59d09a0568
https://doi.org/10.1002/bdr2.2125
https://doi.org/10.1002/bdr2.2125
Publikováno v:
Toxicol Sci
The legalization and increasing availability of cannabis products raises concerns about the impact on offspring of users, and little has appeared on the potential contribution of paternal use. We administered cannabis extract to male rats prior to ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44b3122e981c3d01f6c6e9e5b410cf7
https://doi.org/10.1093/toxsci/kfab117
https://doi.org/10.1093/toxsci/kfab117
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 731-737 (2005)
Exposure to stress during pregnancy influences the trajectory of brain development resulting in permanent alterations that may contribute to increased susceptibility to subsequent cognitive or neuropsychiatric disorders. In this manuscript, we examin
Externí odkaz:
https://doaj.org/article/536db6ac00244f8d89d360b6686972fc
Autor:
Zade Holloway, Cassandra Dean, Reese Koburov, Edward D. Levin, Frederic J. Seidler, Andrew B. Hawkey, Theodore A. Slotkin
Publikováno v:
Neurotoxicol Teratol
A sequence of different classes of synthetic insecticides have been used over the past 70 years. Over this period, the widely-used organochlorines were eventually replaced by organophosphates, with dichlorodiphenyltrichloroethane (DDT) and chlorpyrif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a104fded9724322c837858b23b04e1
https://europepmc.org/articles/PMC8440335/
https://europepmc.org/articles/PMC8440335/
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 174(2)
Little attention has been paid to the potential impact of paternal marijuana use on offspring brain development. We administered Δ9-tetrahydrocannabinol (THC, 0, 2, or 4 mg/kg/day) to male rats for 28 days. Two days after the last THC treatment, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82510d845a10c25b24b2fbd940937b8
https://pubmed.ncbi.nlm.nih.gov/32077955
https://pubmed.ncbi.nlm.nih.gov/32077955
Publikováno v:
Toxicological Sciences. 167:293-304
Tobacco smoke contains polycyclic aromatic hydrocarbons (PAHs) in addition to nicotine. We compared the developmental neurotoxicity of nicotine to that of the PAH archetype, benzo[a]pyrene (BaP), and also evaluated the effects of combined exposure to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2446aa48ee80e476cf5789c160632657
https://doi.org/10.1093/toxsci/kfy241
https://doi.org/10.1093/toxsci/kfy241
Publikováno v:
Toxicology. 408:11-21
Glucocorticoids are given in preterm labor to prevent respiratory distress but these agents evoke neurobehavioral deficits in association with reduced brain region volumes. To determine whether the neurodevelopmental effects are distinct from growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14736b1141e7e83687d7919d49aaea4c
https://doi.org/10.1016/j.tox.2018.06.008
https://doi.org/10.1016/j.tox.2018.06.008
Autor:
Marty Cauley, Edward D. Levin, Hannah White, Shaqif Junaid, Brandon J. Hall, Yael Abreu-Villaça, Theodore A. Slotkin, Abtin Kiany
Publikováno v:
NeuroToxicology. 68:81-87
Tobacco exposure during development leads to neurobehavioral dysfunction in children, even when exposure is limited to secondhand smoke. We have previously shown in rats that developmental exposure to tobacco smoke extract (TSE), at levels mimicking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddb761a0b3ffd0330cb2dcc3b4cb315
https://doi.org/10.1016/j.neuro.2018.07.012
https://doi.org/10.1016/j.neuro.2018.07.012
Publikováno v:
Toxicology. :57-64
Terbutaline and dexamethasone are used in the management of preterm labor, often for durations of treatment exceeding those recommended, and both have been implicated in increased risk of neurodevelopmental disorders. We used a variety of cell models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2853bece6823b5658421e1308fa311
https://doi.org/10.1016/j.tox.2018.03.001
https://doi.org/10.1016/j.tox.2018.03.001