Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Theodore Tselios"'
Autor:
Irini Papazian, Maria Kourouvani, Anastasia Dagkonaki, Vasileios Gouzouasis, Lila Dimitrakopoulou, Nikolaos Markoglou, Fotis Badounas, Theodore Tselios, Maria Anagnostouli, Lesley Probert
Publikováno v:
eLife, Vol 12 (2024)
Autoimmune diseases of the central nervous system (CNS) such as multiple sclerosis (MS) are only partially represented in current experimental models and the development of humanized immune mice is crucial for better understanding of immunopathogenes
Externí odkaz:
https://doaj.org/article/a1739e6e5e644ae1b8dcd59cbe78ae6d
Autor:
Maria Avloniti, Maria Evangelidou, Maria Gomini, Theodore Loupis, Mary Emmanouil, Adamantia Mitropoulou, Theodore Tselios, Hans Lassmann, Agnès Gruart, José M. Delgado-García, Lesley Probert, Vasiliki Kyrargyri
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-28 (2024)
Abstract Background Multiple sclerosis (MS) is a neuroinflammatory demyelinating disease characterized by motor deficits and cognitive decline. Many immune aspects of the disease are understood through studies in the experimental autoimmune encephalo
Externí odkaz:
https://doaj.org/article/9435f7892f354e8a9a7b6c55f8ef658e
Autor:
Christos Markatos, Georgia Biniari, Oleg G. Chepurny, Vlasios Karageorgos, Nikos Tsakalakis, Georgios Komontachakis, Zacharenia Vlata, Maria Venihaki, George G. Holz, Theodore Tselios, George Liapakis
Publikováno v:
Molecules, Vol 29, Iss 17, p 4127 (2024)
The gonadotropin-releasing hormone (GnRH) receptor (GnRH-R) is highly expressed in ovarian cancer cells (OCC), and it is an important molecular target for cancer therapeutics. To develop a new class of drugs targeting OCC, we designed and synthesized
Externí odkaz:
https://doaj.org/article/629b6733c8b64a05a82d4be18e501779
Autor:
Charalampos Ntallis, Haralampos Tzoupis, Theodore Tselios, Christos T. Chasapis, Alexios Vlamis-Gardikas
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 15 (2023)
In silico approaches were employed to examine the characteristics of interactions between human mitochondrial thioredoxin 2 (HsTrx2) and its 38 previously identified mitochondrial protein ligands. All interactions appeared driven mainly by electrosta
Externí odkaz:
https://doaj.org/article/a8c49bf8753a4291b15783124ac280a4
Autor:
Anastasia Dagkonaki, Athina Papalambrou, Maria Avloniti, Areti Gkika, Maria Evangelidou, Maria-Eleni Androutsou, Theodore Tselios, Lesley Probert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autoimmune diseases affecting the CNS not only overcome immune privilege mechanisms that protect neural tissues but also peripheral immune tolerance mechanisms towards self. Together with antigen-specific T cells, myeloid cells are main effector cell
Externí odkaz:
https://doaj.org/article/de53e7d0d54a481fb531d2b4f37bc68f
Autor:
Anastasia Dagkonaki, Maria Avloniti, Maria Evangelidou, Irini Papazian, Ioannis Kanistras, Vivian Tseveleki, Fotis Lampros, Theodore Tselios, Lise Torp Jensen, Wiebke Möbius, Torben Ruhwedel, Maria-Eleni Androutsou, John Matsoukas, Maria Anagnostouli, Hans Lassmann, Lesley Probert
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
CNS autoantigens conjugated to oxidized mannan (OM) induce antigen-specific T cell tolerance and protect mice against autoimmune encephalomyelitis (EAE). To investigate whether OM-peptides treat EAE initiated by human MHC class II molecules, we admin
Externí odkaz:
https://doaj.org/article/01e6e4ce64414d3fbec5f23cf0834a95
Autor:
Iro Triantafyllakou, Nausicaa Clemente, Ravi Kumar Khetavat, Umberto Dianzani, Theodore Tselios
Publikováno v:
Molecular Pharmaceutics. 19:3795-3805
Publikováno v:
Journal of Peptide Science.
Autor:
Athina Konstantinidi, Demeter Tzeli, Andreas G. Tzakos, Sofia Kiriakidi, Ioanna Gerogianni, Dimitrios Kolokouris, Theodore Tselios, Thomas Mavromoustakos, Maria V. Chatziathanasiadou, Ioannis K. Kostakis, Eleni Chontzopoulou, Christina Papaemmanouil, Evangelia D Chrysina, Dimitra Hadjipavlou-Litina
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:12608-12620
Repurposing existing drugs, as well as natural and artificial sweeteners for novel therapeutic indications could speed up the drug discovery process since numerous associated risks and costs for drug development can be surpassed. In this study, natur
Autor:
Theodore Tselios, Mihalis Aggelidakis, Anthi Tapeinou, Vivian Tseveleki, Ioannis Kanistras, Dimitrios Gatos, John Matsoukas
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 17968-17984 (2014)
Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease of the central nervous system and is an animal model of multiple sclerosis (MS). Although the etiology of MS remains unclear, there is evidence T-cell recognition of immunodom
Externí odkaz:
https://doaj.org/article/c76c0bc6598c41e2a3a6f2d37628313c