Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Theodore Faust"'
Publikováno v:
Linear Algebra and its Applications. 626:79-151
Let ‖ A ‖ max : = max i , j | A i , j | denote the maximum magnitude of entries of a given matrix A. In this paper we show that max { ‖ U r ‖ max , ‖ V r ‖ max } ≤ ( C r ) 6 r N , where U r and V r are the matrices whose columns
Autor:
Christopher Manon, Theodore Faust
Publikováno v:
The Electronic Journal of Combinatorics. 26
Using combinatorial methods, we determine that a projective coordinate ring of the moduli of parabolic principal $\mathrm{SL}_2$-bundles on a marked projective curve is not Gorenstein when the genus and number of marked points are greater than $1$.
Autor:
Ryan White, David C. Mcgowan, Xiaotian Zhu, Matthew W. Martin, John Newcomb, John L. Buchanan, Theodore Faust, Faye Hsieh, Xin Huang, Erin F. DiMauro, Susan M. Turci, Christina Boucher, Stephen Schneider, Joseph J. Nunes, Jean Bemis, Josie H. Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2299-2304
2,3-Diarylfuro[2,3-b]pyridine-4-amines are a novel class of potent and selective inhibitors of Lck. The discovery, synthesis, and structure activity relationships of this series of inhibitors are reported. The most promising compounds were also profi
Autor:
David Powers, Huilin Zhao, Li Zhu, Lilly Chai, Theodore Faust, Yan Gu, Yanyan Tudor, Anu Gore, Joseph L. Kim, Xiaotian Zhu, Antonio J. Oliveira-dos-Santos, Xin Huang, Monika Ermann, Susan M. Turci, Paul E. Rose, Debra Zack, Christina Boucher, Linda F. Epstein, Faye Hsieh, John Newcomb, Chiara Ghiron, Andrew A. Welcher, Sylvia Flores, Matthew W. Martin, Paul Gallant, Vinod F. Patel, Kurt Morgenstern, Scot Middleton, Carl-Gustaf Pierre Saluste, David N. Johnston, Joseph J. Nunes
Publikováno v:
Journal of medicinal chemistry. 51(6)
Lck, or lymphocyte specific kinase, is a cytoplasmic tyrosine kinase of the Src family expressed in T-cells and NK cells. Genetic evidence from knockout mice and human mutations demonstrates that Lck kinase activity is critical for T-cell receptor-me
Autor:
Alan C. Cheng, Ryan White, Stephen Schneider, Joseph J. Nunes, John L. Buchanan, Jean Bemis, Faye Hsieh, William H. Buckner, Susan M. Turci, Matthew W. Martin, Christina Boucher, John Newcomb, Xin Huang, Xiaotian Zhu, Josie H. Lee, Theodore Faust, Erin F. DiMauro, David C. Mcgowan, Teresa L. Marshall
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(8)
4-Amino-5,6-biaryl-furo[2,3-d]pyrimidines were identified as potent non-selective inhibitors of Lck. A novel, divergent, and practical synthetic route was developed to access derivatives from bifunctional intermediates. Lead optimization was guided b
Autor:
Debra Zack, David C. Mcgowan, Xiaotian Zhu, Linda F. Epstein, Antonio J. Oliveira-dos-Santos, Ryan White, Christina Boucher, Stephen Schneider, David Powers, Faye Hsieh, Josie H. Lee, Patricia Amouzegh, Huilin Zhao, Spencer Napier, Monika Ermann, Scot Middleton, Daniel Elbaum, Joseph J. Nunes, Xin Huang, Matthew W. Martin, Yanyan Tudor, Paul Gallant, Li Zhu, David N. Johnston, Yan Gu, Kurt Morgenstern, Susan M. Turci, Eoin Christopher Power, Paul E. Rose, Michael Morrison, Theodore Faust, Perry M. Novak, William H. Buckner, Lilly Chai, Jenkins James Edward, Shaun Flynn, John L. Buchanan, Deanna Mohn, Stephanie Sell, Andrew A. Welcher, Daniela Metz, Anu Gore, Chiara Ghiron, John Newcomb, Armistead David M
Publikováno v:
Journal of medicinal chemistry. 49(16)
The lymphocyte-specific kinase (Lck) is a cytoplasmic tyrosine kinase of the Src family expressed in T cells and NK cells. Genetic evidence in both mice and humans demonstrates that Lck kinase activity is critical for signaling mediated by the T cell
Autor:
John Newcomb, John L. Buchanan, Susan M. Turci, Joseph J. Nunes, Xin Huang, Stephen Schneider, Ryan White, Faye Hsieh, Matthew W. Martin, Josie H. Lee, Xiaotian Zhu, David C. Mcgowan, Christina Boucher, Jean Bemis, Erin F. DiMauro, Theodore Faust
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5279
Autor:
Ryan White, Joseph J. Nunes, Josie H. Lee, Matthew W. Martin, Jean Bemis, Susan M. Turci, David C. Mcgowan, Xiaotian Zhu, Christina Boucher, Teresa L. Marshall, Stephen Schneider, John L. Buchanan, Alan C. Cheng, Xin Huang, John Newcomb, Erin F. DiMauro, Theodore Faust, William H. Buckner, Faye Hsieh
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5280
Autor:
Matthew W. Martin, John Newcomb, Joseph J. Nunes, Christina Boucher, Lilly Chai, Linda F. Epstein, Theodore Faust, Sylvia Flores, Paul Gallant, Anu Gore, Yan Gu, Faye Hsieh, Xin Huang, Joseph L. Kim, Scot Middleton, Kurt Morgenstern, Antonio Oliveira-dos-Santos, Vinod F. Patel, David Powers, Paul Rose
Publikováno v:
Journal of Medicinal Chemistry; Feb2008, Vol. 51 Issue 6, p1637-1648, 12p