Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Theodore, Georgomanolis"'
Autor:
Konstantinos Sofiadis, Natasa Josipovic, Milos Nikolic, Yulia Kargapolova, Nadine Übelmesser, Vassiliki Varamogianni‐Mamatsi, Anne Zirkel, Ioanna Papadionysiou, Gary Loughran, James Keane, Audrey Michel, Eduardo G Gusmao, Christian Becker, Janine Altmüller, Theodore Georgomanolis, Athanasia Mizi, Argyris Papantonis
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 6, Pp 1-17 (2021)
Abstract Spatial organization and gene expression of mammalian chromosomes are maintained and regulated in conjunction with cell cycle progression. This is perturbed once cells enter senescence and the highly abundant HMGB1 protein is depleted from n
Externí odkaz:
https://doaj.org/article/1c45f529d5074d11a54d216e9bc18458
Autor:
Lilija Brant, Theodore Georgomanolis, Milos Nikolic, Chris A Brackley, Petros Kolovos, Wilfred van Ijcken, Frank G Grosveld, Davide Marenduzzo, Argyris Papantonis
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 12, Pp 1-8 (2016)
Abstract Mammalian interphase chromosomes fold into a multitude of loops to fit the confines of cell nuclei, and looping is tightly linked to regulated function. Chromosome conformation capture (3C) technology has significantly advanced our understan
Externí odkaz:
https://doaj.org/article/2e4769f6383046958f190470f85f6feb
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Over time eukaryotic genomes have evolved to host genes carrying multiple exons separated by increasingly larger intronic, mostly non-protein-coding, sequences. Initially, little attention was paid to these intronic sequences, as they were considered
Externí odkaz:
https://doaj.org/article/c201bdec53aa4ef3a25e4853ceecdf14
Autor:
Michael Kracht, Knut Beuerlein, Oliver Dittrich-Breiholz, Lilija Brant, Thorsten Stiewe, Helmut Müller, Theodore Georgomanolis, Axel Weber, Tabea Riedlinger, M. Lienhard Schmitz, Wilfred F. J. van IJcken, Argyris Papantonis, Sinah-Sophia Weiterer, Marek Bartkuhn, Ulas Tenekeci, Christin Mayr-Buro, Anna Beyerlein, Hendrik Weiser, Liane Jurida, Johanna Meier-Soelch, Andrea Nist, Athanasia Mizi
Publikováno v:
The EMBO Journal
EMBO Journal, 39(1):e101533. Wiley-Blackwell
EMBO Journal, 39(1):e101533. Wiley-Blackwell
How cytokine‐driven changes in chromatin topology are converted into gene regulatory circuits during inflammation still remains unclear. Here, we show that interleukin (IL)‐1α induces acute and widespread changes in chromatin accessibility via t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0c41122d0cb206c6294c3429b1372b
http://europepmc.org/articles/PMC6939198
http://europepmc.org/articles/PMC6939198
Autor:
Zoi Lygerou, Stavros Taraviras, Georgia Lokka, Argyris Papantonis, Nathalie Spassky, Konstantina Kaplani, Eleni Damianidou, Christina Kyrousi, Evangelia Parlapani, Weilai Dong, Ashley Dunbar, Maria-Eleni Lalioti, Kristopher T. Kahle, Theodore Georgomanolis
Publikováno v:
GliaREFERENCES. 67(12)
The subventricular zone (SVZ) is one of two main niches where neurogenesis persists during adulthood, as it retains neural stem cells (NSCs) with self-renewal capacity and multi-lineage potency. Another critical cellular component of the niche is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5ce4c25c62d41692e7aed3bf0d53b9
https://pubmed.ncbi.nlm.nih.gov/31328313
https://pubmed.ncbi.nlm.nih.gov/31328313
Autor:
Christina Kyrousi, Marina Arbi, Konstantina Kaplani, Argyro Kalogeropoulou, Natasa Josipovic, Zoi Lygerou, Vladimir Benes, Stavros Taraviras, Georgia Lokka, Dimitrios Gkikas, Ioannis Loukas, Athanasia Mizi, Maria-Eleni Lalioti, Panagiotis K. Politis, Theodore Georgomanolis, Argyris Papantonis
Publikováno v:
Journal of cell science. 132(11)
A distinct combination of transcription factors elicits the acquisition of a specific fate and the initiation of a differentiation program. Multiciliated cells (MCCs) are a specialized type of epithelial cells that possess dozens of motile cilia on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c90daf5560355d7418bfd5bab9d12b
https://pubmed.ncbi.nlm.nih.gov/31028178
https://pubmed.ncbi.nlm.nih.gov/31028178
Autor:
Agapios Sachinidis, Natalia Emilse Vargas, Juergen Hescheler, Julia Franzen, Ivan G. Costa, Deniz Bartsch, Marie Gramm, Lilija Brant, Argyris Papantonis, Alvaro Rada-Iglesias, Joseph Chao-Chung Kuo, Nicole Russ, Meena Kanduri, Tsun-Po Yang, Chandrasekhar Kanduri, Jens-Peter Derks, Leo Kurian, Gaurav Ahuja, Jan-Erik Messling, Theodore Georgomanolis, Wenjie Yao, Rizwan Rehimi, Stefan Frank, Yulia Kargapolova, Martin Peifer, Vijay Suresh Akhade, Raja Ghazanfar Ali Sahito, Alina Kuroczik
Publikováno v:
Cell stem cell. 24(2)
Human protein-coding genes are often accompanied by divergently transcribed non-coding RNAs whose functions, especially in cell fate decisions, are poorly understood. Using an hESC-based cardiac differentiation model, we define a class of divergent l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac29369f1efc75f28b1058582b5e2dc
https://pubmed.ncbi.nlm.nih.gov/30554961
https://pubmed.ncbi.nlm.nih.gov/30554961
Autor:
Henrike Johanna Gothe, Vassilis Roukos, Jan-Philipp Mallm, Ivan G. Costa, Anne Zirkel, Oliver Drechsel, Lilija Brant, Chris A. Brackley, Karsten Rippe, Davide Marenduzzo, Argyris Papantonis, Konstantinos Sofiadis, Mirjam Koker, Peter Nürnberg, Roland T. Ullrich, Eduardo G. Gusmao, Milos Nikolic, Janine Altmüller, Julia Franzen, Christian Becker, Theodore Georgomanolis, Wolfgang Wagner
Publikováno v:
SSRN Electronic Journal.
Ageing-relevant processes, like cellular senescence, are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular events that trigger such cascades remain elusive. We hypothesized that senescence ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::087a161244cf570e0f3ed1fa636b7c1d
https://doi.org/10.2139/ssrn.3155934
https://doi.org/10.2139/ssrn.3155934
Autor:
Anne Zirkel, Shona Murphy, Sarah D. Diermeier, Peter R. Cook, Theodore Georgomanolis, Steven L. Kelly, Argyris Papantonis, Dawn O'Reilly, Gernot Längst
Publikováno v:
Nucleic Acids Research
The conventional model for splicing involves excision of each intron in one piece; we demonstrate this inaccurately describes splicing in many human genes. First, after switching on transcription of SAMD4A, a gene with a 134 kb-long first intron, spl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f704abc7c5f00e6e5b0e423625b9e3f
https://ora.ox.ac.uk/objects/uuid:78fd8130-1420-43b9-91ef-0921dabc44e2
https://ora.ox.ac.uk/objects/uuid:78fd8130-1420-43b9-91ef-0921dabc44e2
Autor:
Argyris Papantonis, Milos Nikolic, Petros Kolovos, Chris A. Brackley, Frank Grosveld, Lilija Brant, Theodore Georgomanolis, Davide Marenduzzo, Wilfred F. J. van IJcken
Publikováno v:
Molecular Systems Biology, 12(12):891. Wiley-Blackwell
Molecular Systems Biology
EUR Research Portal
Brant, L, Georgomanolis, T, Nikolic, M, Brackley, C A, Kolovos, P, van Ijcken, W, Grosveld, F G, Marenduzzo, D & Papantonis, A 2016, ' Exploiting native forces to capture chromosome conformation in mammalian cell nuclei ', Molecular Systems Biology, vol. 12, no. 12, pp. 891 . https://doi.org/10.15252/msb.20167311
University of Copenhagen
Molecular Systems Biology
EUR Research Portal
Brant, L, Georgomanolis, T, Nikolic, M, Brackley, C A, Kolovos, P, van Ijcken, W, Grosveld, F G, Marenduzzo, D & Papantonis, A 2016, ' Exploiting native forces to capture chromosome conformation in mammalian cell nuclei ', Molecular Systems Biology, vol. 12, no. 12, pp. 891 . https://doi.org/10.15252/msb.20167311
University of Copenhagen
Mammalian interphase chromosomes fold into a multitude of loops to fit the confines of cell nuclei, and looping is tightly linked to regulated function. Chromosome conformation capture (3C) technology has significantly advanced our understanding of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5925b8d926716982a3b1bbbce1cad433
https://pure.eur.nl/en/publications/af3df48c-d39a-4f93-9253-c996c65277b7
https://pure.eur.nl/en/publications/af3df48c-d39a-4f93-9253-c996c65277b7