Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Theodora Kladis"'
Publikováno v:
Neurobiology of Aging. 27:857-861
Parkinson's disease is characterized by bradykinesia, rigidity and a resting tremor and the underlying basis for those symptoms is the loss of dopaminergic cells in the nigrostriatal system. Similar to PD, an age-related decrease locomotor activity a
Autor:
Leah Novak, Heather C. Salzberg-Brenhouse, Anthony S. Basile, Brigido Perdomo, Raymond T. Bartus, Jeffrey H. Kordower, Sam Baldwin, Theodora Kladis, Karen Fu, Sharon Ranelli, Er-Yun Chen, Denise Lafreniere, Ken Hogeland, Dwaine F. Emerich
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 306:218-228
Cyclooxygenases (COXs) are implicated in neurodegenerative processes associated with acute and chronic neurological diseases. Given the potential utility of COX inhibitors in treating these disorders, we examined the nonselective COX inhibitor flurbi