Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Theodora G.A. Solovou"'
Autor:
Joseph Hayes, Georgia Moschou, Vasiliki T Skamnaki, Theodora G.A. Solovou, Caroline H Topham, Thowaiba Babikr Ahmed Alta, Timothy J. Snape, Christopher Lawson
Publikováno v:
European journal of medicinal chemistry. 225
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Medulloblastoma – highly aggressive and heterogeneous tumours of the cerebellum – account for 15-2
Autor:
Éva Bokor, Spyros E. Zographos, Georgios A Stravodimos, Anastassia L. Kantsadi, Tibor Docsa, László Somsák, Andrea Szakács, Efthimios Kyriakis, Theodora G.A. Solovou, Demetres D. Leonidas, Katalin E. Szabó, Csenge Koppány, Pál Gergely, Vassiliki T. Skamnaki
Publikováno v:
Journal of Medicinal Chemistry. 60:9251-9262
Aryl substituted 1-(β-d-glucosaminyl)-1,2,3-triazoles as well as C-β-d-glucosaminyl 1,2,4-triazoles and imidazoles were synthesized and tested as inhibitors against muscle and liver isoforms of glycogen phosphorylase (GP). While the N-β-d-glucosam
Autor:
Charalambos Bobas, Georgios Papadopoulos, Constantine Garagounis, Kalliope K. Papadopoulou, Theodora G.A. Solovou, Efthimios Kyriakis, Demetres D. Leonidas, Vassiliki T. Skamnaki
Publikováno v:
Phytochemistry. 186:112707
The glycogen synthase kinases 3 family (GSK3s/SKs; serine/threonine protein kinases) is conserved throughout eukaryotic evolution from yeast to plants and mammals. We studied a plant SK kinase from Lotus japonicus (LjSK1), previously implicated in no
Autor:
Eszter Szennyes, Efthimios Kyriakis, Vassiliki T. Skamnaki, Olga Papaioannou, Éva Bokor, Theodora G.A. Solovou, Spyros E. Zographos, László Somsák, Panagiota G.V. Liggri, Demetres D. Leonidas, Sándor Kun, Aikaterini G. Karra, Anna-Maria G. Psarra
Publikováno v:
Bioorganicmedicinal chemistry. 28(1)
C-Glucopyranosyl imidazoles, thiazoles, and an N-glucopyranosyl tetrazole were assessed in vitro and ex vivo for their inhibitory efficiency against isoforms of glycogen phosphorylase (GP; a validated pharmacological target for the development of ant
Autor:
Panagiota G.V. Liggri, Theodora G.A. Solovou, Anna-Maria G. Psarra, George A. Stravodimos, Anna Apostolou, Vyron A. Gorgogietas, Chariklia Psachoula, Angelos Lemonakis, Demetres D. Leonidas, Serkos A. Haroutounian, Apostolia Kissa, Pagona Gatzona, Demetra S.M. Chatzileontiadou, Vassiliki Nafsika Kafaski-Kanelli, Vassiliki T. Skamnaki, Anastassia L. Kantsadi, Efthimios Kyriakis, Stavroula Theofanous
Publikováno v:
Current drug discovery technologies. 15(1)
BACKGROUND Glycogen phosphorylase (GP) is a pharmaceutical target for the discovery of new antihyperglycaemic agents. Punica granatum is a well-known plant for its potent antioxidant and antimicrobial activities but so far has not been examined for a
Autor:
Demetra S.M. Chatzileontiadou, Éva Bokor, Anastassia L. Kantsadi, Demetres D. Leonidas, Efthimios Kyriakis, Theodora G.A. Solovou, Sándor Kun, George A. Stravodimos, László Somsák
3-(C-Glucopyranosyl)-5aryl-1,2,4-triazoles with an aryl moiety larger than phenyl have been shown to have strong inhibitory potency (Ki values in the range of upper nM) for human liver glycogen phosphorylase (hlGP), a pharmacologically relevant targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bd1ff99bdef2f69e0666418c4d2208