Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Theodora Chatzisideri"'
Autor:
Theodora Chatzisideri, George Leonidis, Theodoros Karampelas, Eleni Skavatsou, Angeliki Velentza-Almpani, Francesca Bianchini, Constantin Tamvakopoulos, Vasiliki Sarli
Publikováno v:
Journal of Medicinal Chemistry. 65:271-284
c(RGDyK)-based conjugates of gemcitabine (GEM) with the carbonate and carbamate linkages in the 6-OH group of GEM were synthesized for the targeted delivery of GEM to integrin α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8d9bbffe24b7eefa8283c50b24c88a
https://doi.org/10.1021/acs.jmedchem.1c01468
https://doi.org/10.1021/acs.jmedchem.1c01468
Autor:
Theodora Chatzisideri, Francesca Bianchini, Panagiotis Dalezis, Dimitrios T. Trafalis, Vasiliki Sarli, Spyridon Bousis, George Leonidis
Publikováno v:
Future Medicinal Chemistry. 13:877-895
Cucurbitacins (CUCUs) are triterpenoids known to display potent cytotoxic effects; however, their clinical application is limited due to poor pharmacokinetics and systemic toxicity. This work focuses on the development of c(RGDyK)–CUCU conjugates f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5079274177a2236dfe51e8d554d9a4d
https://doi.org/10.4155/fmc-2020-0309
https://doi.org/10.4155/fmc-2020-0309
Autor:
Savvas Thysiadis, Theodora Chatzisideri, Sotirios Katsamakas, Dimitrios T. Trafalis, Panagiotis Dalezis, Vasiliki Sarli
Publikováno v:
Future Medicinal Chemistry. 9:2181-2196
Aim: Alkylating agents and antimetabolites are cytotoxic drugs commonly used in cancer treatment. These medications are often associated with serious side effects on normal tissues and organs. Methodology: To improve the pharmacological profile of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8a040b98356dbf3e86298b6dc7a545
https://doi.org/10.4155/fmc-2017-0139
https://doi.org/10.4155/fmc-2017-0139
Autor:
Sotirios Katsamakas, Eleni Nikolakaki, Theodore Lazarides, Theodora Chatzisideri, Panagiotis Dalezis, Vasiliki Sarli, Savvas Thysiadis, Ioanna Sigala, Dimitrios T. Trafalis, Mikael Lindgren, Odrun A. Gederaas
Publikováno v:
European Journal of Medicinal Chemistry. 141:221-231
A cancer-targeting conjugate 4 of a cyclometalated [N,C,N-Pt(II)] complex bearing a NˆCˆN 1,3-di(2-pyridyl)-benzene with c(RGDyK) peptide as guiding molecule was designed and synthesized for real-time drug delivery monitoring in cancer cells and ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99451858b0881e4b90194ebd8e40142b
https://doi.org/10.1016/j.ejmech.2017.09.058
https://doi.org/10.1016/j.ejmech.2017.09.058
Publikováno v:
Future Medicinal Chemistry. 9:579-604
Conjugates of cytotoxic agents with RGD peptides (Arg-Gly-Asp) addressed to ανβ3, α5β1and ανβ6integrin receptors overexpressed by cancer cells, have recently gained attention as potential selective anticancer chemotherapeutics. In this review
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0893ac97cd7dfbadcd2a0798161ede
https://doi.org/10.4155/fmc-2017-0008
https://doi.org/10.4155/fmc-2017-0008
Publikováno v:
Future medicinal chemistry. 10(18)
There is a growing interest for the discovery of new cancer-targeted delivery systems for drug delivery and diagnosis. A synopsis of the bibliographic data will be presented on bombesin, neurotensin, octreotide, Arg-Gly-Asp, luteinizing hormone-relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0318a9000f92e80e1ddc1823127cef0d
https://pubmed.ncbi.nlm.nih.gov/30043641
https://pubmed.ncbi.nlm.nih.gov/30043641