Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Theodora, Germetaki"'
Autor:
Sara Valpione, Luca G. Campana, John Weightman, Zena Salih, Elena Galvani, Piyushkumar A. Mundra, Francesco De Rosa, Avinash Gupta, Patricio Serra-Bellver, Paul Lorigan, Theodora Germetaki, Marek Dynowski, Stephen Kitcatt, Sudhakar Sahoo, Dave Lee, Nathalie Dhomen, Graham Lord, Richard Marais
Publikováno v:
European Journal of Cancer. 177:164-174
Immune cell-driven anti-cancer activity is paramount for effective responses to checkpoint inhibitors (ICB). However, the contribution of the different immune cell subsets in the circulation and within the tumour is poorly understood.To elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93cb67eaad51bf7237217ba2d184124c
https://doi.org/10.1016/j.ejca.2022.09.022
https://doi.org/10.1016/j.ejca.2022.09.022
Autor:
Kok Haw Jonathan Lim, Panagiotis Ntellas, Daniel Anderson, Lilly Simpson, Michael Braun, Marios Adamou, Jorge Barriuso, Katerina Dadouli, Jacqueline Connell, Joseph Williams, Theodora Germetaki, Deirdre Lehwald, Niall Fitzpatrick, Mark Cutting, Danielle McCool, Jurjees Hasan, Saifee Mullamitha, Kalena Marti, Mark Saunders, Konstantinos Kamposioras
Publikováno v:
Cancers
Volume 15
Issue 4
Pages: 1226
Volume 15
Issue 4
Pages: 1226
The COVID-19 pandemic has resulted in unprecedented changes to the lives of patients with cancer. To evaluate the impact of the COVID-19 pandemic on the mental health and well-being of patients with colorectal cancer, we conducted a prospective longi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95570240458d0c3d0daffdccf7b36975
Autor:
Katerina Dadouli, Panagiotis Ntellas, George Zarkavelis, Anna-Lea Amylidi, Konstantinos Kamposioras, Theodora Germetaki, Ioanna Gazouli, Maria Tolia, Michail Nikolaou, Davide Mauri
Publikováno v:
JNCI Cancer Spectrum
BackgroundThe therapeutic role of immune checkpoint inhibitors (ICIs) has represented the cutting edge of clinical research in upper gastrointestinal (GI) malignancies, with these agents now included in the armamentarium of treatment options for adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0ce8bf75f7de5542c8ac840998ade6
https://doi.org/10.1093/jncics/pkab088
https://doi.org/10.1093/jncics/pkab088
Autor:
Jane Rogan, Sharzad Moghadam, Theodora Germetaki, M. Braun, Mark P Saunders, Antje Lukas, Eva Lenfert, Daniel L. Edelstein, Camille Nicholls, Frederick S. Jones, Richard Adams
Aim: To determine the concordance between plasma and tissue RAS mutation status in metastatic colorectal cancer patients to gauge whether blood-based testing is a viable alternative. We also evaluated the change in mutation status on progression. Mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd86098bcb9c7183b5d6c65414b80b00
https://orca.cardiff.ac.uk/id/eprint/141030/1/fon-2020-0523.pdf
https://orca.cardiff.ac.uk/id/eprint/141030/1/fon-2020-0523.pdf
Autor:
Theodora, Germetaki, Camille, Nicholls, Richard A, Adams, Michael, Braun, Jane, Rogan, Sharzad, Moghadam, Eva, Lenfert, Antje, Lukas, Daniel L, Edelstein, Frederick S, Jones, Mark P, Saunders
Publikováno v:
Future oncology (London, England). 16(28)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c439ec3a2cc502ba39f67d2df997bed
https://pubmed.ncbi.nlm.nih.gov/32716216
https://pubmed.ncbi.nlm.nih.gov/32716216
Autor:
Sofia Stamatopoulou, Magdy Nasralla, Vikki Owen-Holt, George Papaxoinis, Alan Anthoney, Theodora Germetaki, Zoe Kordatou, Wasat Mansoor, Jamie M J Weaver, Konstantinos Kamposioras
Publikováno v:
Journal of Gastrointestinal Surgery. 23:1729-1741
The aim of this cohort study was to assess the benefit that patients with lower esophageal or gastroesophageal junction (E/GEJ) adenocarcinoma receive by continuing perioperative chemotherapy post-surgery. Three hundred twelve patients underwent radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540b4c15371437dd40da9f3bf673ec4e
https://doi.org/10.1007/s11605-018-04087-8
https://doi.org/10.1007/s11605-018-04087-8
Autor:
Jill Fenwick, Mark P Saunders, Abigail Garbutt, Michael Braun, Mary Judge, Theodora Germetaki, Nina Paton, Janette Beech, Joanne Collins
Publikováno v:
Future Oncology. 14:2531-2541
Cutaneous toxicities associated with EGFR inhibitors (EGFRIs) have a significant impact on patient treatment continuation, quality of life and healthcare resource utilization. This paper reviews the current prophylaxis and management of EGFRI-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68a1cbc89424999360fbe53762151b5
https://doi.org/10.2217/fon-2018-0187
https://doi.org/10.2217/fon-2018-0187
Autor:
Leila Khoja, Theodora Germetaki, Ana Patrao, Zoe Kordatou, Alia Alchawaf, George Papaxoinis, Sofia Stamatopoulou, Jamie M J Weaver, Vikki Owen-Holt, Wasat Mansoor
Publikováno v:
Acta Oncologica. 56:1224-1232
The new American Joint Committee on Cancer eighth edition (AJCC8) staging is the first to describe separate clinical and pathology staging systems, but still has low performance to predict prognosis in patients with oesophageal/gastroesophageal junct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e30de2076439fd867d95ae5adc4396a
https://doi.org/10.1080/0284186x.2017.1328127
https://doi.org/10.1080/0284186x.2017.1328127
Autor:
George Papaxoinis, Vikki Owen-Holt, Zoe Kordatou, Jamie M J Weaver, Konstantinos Kamposioras, Magdy Nasralla, Theodora Germetaki, Alan Anthoney, Wasat Mansoor, Sofia Stamatopoulou
Publikováno v:
Acta oncologica (Stockholm, Sweden). 57(6)
Thromboembolic events (TEEs) represent a significant treatment and disease complication for cancer patients. In the present study we assessed the incidence of TEEs in patients receiving preoperative chemotherapy for esophagogastric adenocarcinoma. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896f83ea9c5809e74a4cafd267b9bc7e
https://pubmed.ncbi.nlm.nih.gov/29308947
https://pubmed.ncbi.nlm.nih.gov/29308947
Autor:
M. Rigby, P. Jeffrey, Manreet Randhawa, S. Blakemore, Gavin Bennett, Udai Banerji, Maria Koehler, Natalie Cook, Marc Pittman, Theodora Germetaki, A. Biondo, J. Evans, Stefan Symeonides, Lisa Godfrey, A. Niewiarowski, S. Leslie
Publikováno v:
Cook, N, Banerji, U, Evans, J, Biondo, A, Germetaki, T, Randhawa, M, Godfrey, L, Leslie, S, Jeffrey, P, Rigby, M, Bennett, G, Blakemore, S, Koehler, M, Niewiarowski, A, Pittman, M & Symeonides, S N 2019, ' Pharmacokinetic (PK) assessment of BT1718: A phase I/II a study of BT1718, a first in class bicycle toxin conjugate (BTC), in patients (pts) with advanced solid tumours ', Annals of Oncology, vol. 30, pp. v174 . https://doi.org/10.1093/annonc/mdz244.026
Background BT1718 contains a constrained bicyclic peptide with high affinity and selectivity for cell surface target MT1-MMP (MMP14) linked to a toxin (DM1) via a cleavable disulphide linker. BT1718 has demonstrated significant anti-tumor activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c205953c46f74d6e35238a02efddc1
https://doi.org/10.1093/annonc/mdz244.026
https://doi.org/10.1093/annonc/mdz244.026