Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Theodor A Woolman"'
Autor:
Dalian Ding, Guang-Di Chen, Richard Salvi, Damian M. Daszynski, Haiyan Jiang, Theodor A Woolman, Karen Blessing, Peter F. Kador
Publikováno v:
Hear Res
Oxidative stress is a major contributor to noise-induced hearing loss, the most common cause of hearing loss among military personnel and young adults. HK-2 is a potent, orally-active, multifunctional, redox-modulating drug that has been shown to pro
Autor:
Karen Blessing, Hiroyoshi Kawada, Tomomi Kiyota, Peter F. Kador, Lee C. Winchester, Theodor A Woolman
Publikováno v:
Journal of Alzheimer's Disease. 44:297-307
Background Redox-active metal dyshomeostasis and oxidative stress are associated with mitochondrial dysfunction and amyloid-β (Aβ) neurotoxicity that are linked to both the development of age-related macular degeneration (AMD) and Alzheimer's disea
Publikováno v:
Current topics in medicinal chemistry. 13(11)
Molecular properties such as the molecular weight, hydrophobicity parameter logP, and the total polar surface area (TPSA) have been used extensively in modern drug discovery. We investigated these properties and ADMET scores of the top 200 therapeuti